| National Cancer Institute "Cancer Moonshot Biobank" |
Biospecimen Collection, Medical Chart Review |
Recruiting |
| Testing the Effects of Low Dose Apalutamide on Prostate-Specific Antigen (PSA) Levels in Men Scheduled for Removal of the Prostate Gland |
Apalutamide, Quality-of-Life Assessment, Biospecimen Collection |
Recruiting |
| Role of Lisinopril in Preventing the Progression of Non-Alcoholic Fatty Liver Disease, RELIEF-NAFLD Study |
Lisinopril, Questionnaire Administration, Biospecimen Collection, Liver Ultrasonographic Elastography, Magnetic Resonance Elastography, Magnetic Resonance Imaging, Proton Density Fat Fraction |
Recruiting |
| Retinoid 9cUAB30 in Producing a Biologic Effect in Patients With Early Stage Breast Cancer |
Biospecimen Collection, Retinoid 9cUAB30, Therapeutic Conventional Surgery |
Active, not recruiting |
| Preventive Human Papillomavirus (HPV) Vaccine Trial in Kidney Transplant Recipients |
Biospecimen Collection, HPV Self-Collection, Questionnaire Administration, Recombinant Human Papillomavirus Nonavalent Vaccine |
Active, not recruiting |
| Biospecimen Collection in Identifying Genetic Changes in Patients With Breast, Prostate, Colorectal, Liver, or Kidney Cancer or Multiple Myeloma Undergoing Surgery |
Biospecimen Collection, Laboratory Biomarker Analysis |
Recruiting |
| Testing the Effect of the Broccoli Seed and Sprout Extract, Avmacol ES, on the Cancer Causing Substances of Tobacco in Heavy Smokers |
Biospecimen Collection, Broccoli Sprout/Broccoli Seed Extract Supplement, Placebo Administration, Questionnaire Administration |
Recruiting |
| Cancer Preventive Vaccine Nous-209 for Lynch Syndrome Patients |
Adenoviral Tumor-specific Neoantigen Priming Vaccine GAd-209-FSP, Biospecimen Collection, Endoscopic Biopsy, MVA Tumor-specific Neoantigen Boosting Vaccine MVA-209-FSP, Questionnaire Administration |
Recruiting |
| Phase I Trial of Endoxifen Gel Versus Placebo in Women Undergoing Breast Surgery |
Endoxifen Hydrochloride, Placebo Administration, Questionnaire Administration |
Active, not recruiting |
| Metformin for Chemoprevention of Lung Cancer in Overweight or Obese Individuals at High Risk for Lung Cancer |
Extended Release Metformin Hydrochloride, Biopsy, Biospecimen Collection, Bronchoscopy, Questionnaire Administration |
Recruiting |
| Topical Fluorouracil and Imiquimod in Treating Patients With High-Grade Cervical Intraepithelial Neoplasia |
Imiquimod, Topical Fluorouracil |
Active, not recruiting |
| Testing Atorvastatin to Lower Colon Cancer Risk in Longstanding Ulcerative Colitis |
Atorvastatin Calcium, Biopsy of Colon, Biospecimen Collection, Placebo Administration, Questionnaire Administration |
Recruiting |
| Testing Obeticholic Acid for Familial Adenomatous Polyposis |
Biopsy, Obeticholic Acid, Placebo Administration, Biospecimen Collection, Gastrointestinal Endoscopy, Questionnaire Administration |
Recruiting |
| MUC1 Vaccine in Preventing Lung Cancer in Current and Former Smokers at High Risk for Lung Cancer |
MUC1 Peptide-Poly-ICLC Vaccine, Laboratory Biomarker Analysis |
Active, not recruiting |
| Testing a Combination of Vaccines for Cancer Prevention in Lynch Syndrome |
Adenovirus 5 CEA/MUC1/Brachyury Vaccine Tri-Ad5, Biopsy, Biospecimen Collection, Colonoscopy, Nogapendekin Alfa, Placebo Administration, Questionnaire Administration |
Recruiting |
| Acolbifene Versus Low Dose Tamoxifen for the Prevention of Breast Cancer in Premenopausal Women at High Risk for Development of Breast Cancer |
Biospecimen Collection, Tamoxifen, Random Periareolar Fine-Needle Aspiration, Acolbifene Hydrochloride, Mammography |
Not yet recruiting |
| Testing the Efficacy of Topical Calcipotriene Plus 5-Fluorouracil Combination to Activate the Immune System Against Precancerous Skin Lesions in Organ Transplant Recipients |
Biopsy, Calcipotriene, Fluorouracil |
Not yet recruiting |
| Testing ONC201 to Prevent Colorectal Cancer |
Biospecimen Collection, Biopsy, Colonoscopy, Sigmoidoscopy, Questionnaire Administration, Dordaviprone |
Not yet recruiting |
| Study to Determine Possible Effects of Apalutamide on EGFR Expression in Patients With Non-muscle Invasive Bladder Cancer |
Apalutamide, Biospecimen Collection, Questionnaire Administration, Transurethral Resection of Bladder Tumor |
Not yet recruiting |
| Oral Iloprost for the Prevention of Lung Cancer In Former Smokers |
Biospecimen Collection, Placebo Administration, Bronchial Brush Biopsy, Iloprost, Questionnaire Administration, Bronchoscopy |
Not yet recruiting |