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Dear Colleague, The spring issue of Nutrition Frontiers showcases the association of gut microbial communities in premenopausal women, how high-fat, high-calorie-diet-induced obesity may increase pancreatic cancer, and the... Read More

POSTED: 05/14/2018

The NCI Cancer Prevention Fellowship Program (CPFP), which supports postdoctoral research and leadership training, is accepting applications for the fellows’ class that starts in 2019. The application period is open until... Read More

POSTED: 05/10/2018

A photo of CPFP fellows at the NCI Shady Grove campus.

Study Shows Experimental Screening Test Can Detect Endometrial and Ovarian Cancers

Researchers have shown that an experimental screening test can detect some endometrial and ovarian cancers at their early, more treatable stages. The test, called PapSEEK, is a type of liquid biopsy that identifies cancer-... Read More

POSTED: 05/02/2018

PapSEEK detects genetic alterations in DNA that ovarian and endometrial tumors have shed into the uterus, cervix, and blood (plasma).

Division of Cancer Prevention Director Barry Kramer, MD, MPH, answers questions about cancer overdiagnosis. Q: What is cancer overdiagnosis? A: Cancer overdiagnosis is the detection of asymptomatic cancers, often through... Read More

POSTED: 04/23/2018

Overdiagnosis occurs when screen-detected cancers are either non-growing or so slow-growing that they would never cause medical problems.

The Finding Cancer Trials Collaborative

Imagine a day when a cancer patient can find relevant cancer clinical trials with ease. We invite the entire cancer community – including patients, advocates, clinical trialists, industry, and NCI – to achieve this vision... Read More

POSTED: 04/16/2018

Finding Cancer Trials Collaborative

The PREVENT Cancer Preclinical Drug Development Program (PREVENT) is a peer-reviewed program designed to support development of the best ideas in cancer prevention using National Cancer Institute contract resources. The... Read More

POSTED: 04/13/2018

Interactive App Improves Colorectal Cancer Screening Rates

Although screening for colorectal cancer has been shown to decrease deaths from the disease, only about two-thirds of Americans are up to date with screening. Now a new study suggests that giving people an easy way to order... Read More

POSTED: 04/09/2018

An image of man researching colorectal cancer screening rates on a tablet.

NCI Launches New Resource for Specimens and Data from Cancer Clinical Trials

NCI announced the launch today of a new resource for cancer researchers interested in conducting studies using specimens and clinical data collected from cancer treatment trials in NCI’s National Clinical Trials Network (... Read More

POSTED: 04/02/2018

Through the Navigator program, cancer researchers can study biological specimens, including blood and tissue samples, collected as part of NCI-funded phase 3 clinical trials.

Higher Risk of Heart Failure Seen in Some Cancers

Some people who have been treated for breast cancer or lymphoma have a higher risk of developing congestive heart failure than people who haven't had cancer, results from a new study show. Read More

POSTED: 03/26/2018

Within 5 year of diagnosis, people treated for lymphoma or breast cancer were 3 times as likely to develop heart failure as people who never had cancer.

Recognizing HPV Awareness Day

Cervical cancer is the fourth most common cancer in women worldwide, with over 500,000 new cases estimated each year. Although the global burden is great, it is not equally distributed between nations – more than 85% of... Read More

POSTED: 02/27/2018

Dear Colleague, The winter issue of Nutrition Frontiers showcases the chemopreventive activity of sulforaphane, how a high fat, high cholesterol diet may impact hepatocellular carcinoma, and p53 activation from benzyl... Read More

POSTED: 02/14/2018

Study Identifies Potential Cause of Hearing Loss from Cisplatin

Results from a new study may explain why many patients treated with the chemotherapy drug cisplatin develop lasting hearing loss. Researchers found that, in both mice and humans, cisplatin can be found in the cochlea—the... Read More

POSTED: 01/26/2018

A slide displaying how chemotherapy drug cisplatin (in green) occurs in a mouse inner ear.

The Challenging Landscape of Cancer and Aging: Charting a Way Forward

Earlier this month, I had the privilege of giving two scientific talks: one at a Grand Rounds lecture hosted by NCI’s Center for Cancer Research, and a second held at the Sidney Kimmel Comprehensive Cancer Center at Johns... Read More

POSTED: 01/24/2018

Image of a couple walking outdoors.

Acupuncture May Reduce Treatment-Related Joint Pain for Breast Cancer Patients

Acupuncture can reduce joint pain caused by drugs called aromatase inhibitors, according to results from a large, rigorous study of this approach in postmenopausal women with early-stage breast cancer.Read the article Read More

POSTED: 01/08/2018

An image of acupuncturist inserting a needle into a patient.

Questions at the heart of the Tomosynthesis Mammographic Imaging Screening Trial (TMIST) were highlighted in recent media coverage. The large NCI-funded trial administered by NCORP research base ECOG-ACRIN, is comparing... Read More

POSTED: 12/07/2017

An Asian female technician positions an African-American woman at an imaging machine to receive a mammogram.

In the largest, most rigorous study of its kind, acupuncture was found to significantly reduce the debilitating joint pain experienced by tens of thousands of women each year while being treated for early stage breast... Read More

POSTED: 12/07/2017

Experimental Ovarian Cancer Vaccine Shows Promise in Mice

In mouse studies, an experimental vaccine strategy has shown promise for preventing ovarian cancer. The vaccine targets a protein that is present at elevated levels in approximately 90% of human ovarian epithelial cancers,... Read More

POSTED: 11/17/2017

An experimental vaccine against ovarian cancer targets a "retired" protein that is found at elevated levels in many ovarian cancers.

Liquid Biopsy: Using DNA in Blood to Detect, Track, and Treat Cancer

When a patient has a suspicious lump or symptoms, one of the first things a doctor may do is perform a tissue biopsy—a procedure to collect cells for closer examination. Examining the appearance of the cells under the... Read More

POSTED: 11/08/2017

A laboratory technician's gloved hand lifts a test tube sample with blood inside.

The National Institutes of Health (NIH) is seeking the research community’s input through a Request for Information (RFI) about areas of scientific opportunity that would benefit from the unique research resources of the... Read More

POSTED: 11/06/2017

Aerial view of the National Institutes of Health Clinical Center (Building 10) in Bethesda, Maryland.

Senator John McCain (R-AZ) made remarks on the Senate on October 31 thanking and praising all of the professionals and administrators at NCI, for both treating his brain cancer and for supporting cancer research around the... Read More

POSTED: 11/02/2017

Dear Colleague, The fall issue of Nutrition Frontiers showcases the effect of green tea supplements on liver enzyme elevations, how the combination of cisplatin and sulforaphane may be useful in epidermal squamous cell... Read More

POSTED: 10/31/2017

TMIST Trial Aims to Provide Clarity on Breast Cancer Screening Approaches

A large nationwide clinical trial has been launched to try to answer some important questions about the technologies used to screen for breast cancer. Known as the Tomosynthesis Mammographic Imaging Screening Trial, or TMIST... Read More

POSTED: 10/30/2017

Breast nodules detected during screening by standard 2D digital mammogram (left) and tomosynthesis (right).

There are 3 new funding opportunity announcements about the Pre-Cancer Atlas associated with the Beau Biden Cancer MoonshotSM Initiative that are intended to accelerate cancer research. The purpose of the FOAs is to... Read More

POSTED: 10/23/2017

Infographic of the Pre-Cancer Atlas

Tomosynthesis Mammographic Imaging Screening Trial (TMIST)

The Tomosynthesis Mammographic Imaging Screening Trial (TMIST), the first randomized trial to compare two types of digital mammography for breast cancer screening, is now open for enrollment. TMIST researchers are enrolling... Read More

POSTED: 09/26/2017

An image of a researcher viewing a digital mammography for breast cancer screening.

The third year of NCI’s Community Oncology Research Program (NCORP) was a charm as the community sites and research bases ramped up activities across the board, NCORP Director Worta McCaskill-Stevens, MD, told the network’... Read More

POSTED: 09/15/2017

NCORP Director Worta McCaskill-Stevens, MD presents the 2017 Harry Hynes Award to Patrick J. Flynn, MD, of the Metro-Minnesota NCORP.

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