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An over-the-counter drug, readily available to consumers for years, may open a new option for preventing colorectal cancer in high-risk individuals. It's not the mouse that roared but the quiet mouse behind the scenes that... Read More

POSTED: 02/03/2021
SOURCE: Cancer Prevention Science Blog

A bottle of Naproxen placed atop a table with some tablets displayed.

Early Detection Research Network Marks 20 Years

This month, the Early Detection Research Network (EDRN) marks its 20th anniversary. The National Cancer Institute (NCI) launched the network in 2000 with the goal of identifying and harnessing biomarkers as a way of... Read More

POSTED: 12/21/2020
SOURCE: AACR Cancer Research Cataylst Blog

Histological slide (H & E stain at x300) showing prostate cancer.

As this unforgettable year of 2020 comes to an end, I am reaching the milestone of my first 6 months as Director of the NCI Division of Cancer Prevention (DCP). It has been a whirlwind of virtual meetings and introductions.... Read More

POSTED: 12/17/2020
SOURCE: Cancer Prevention Science Blog

Portrait of Philip E. Castle, Ph.D., M.P.H.

The SWOG Cancer Research Network is opening to accrual the MiCHOICE Trial to study the use of decision support tools by women with high-risk breast conditions and their healthcare providers to choose among chemoprevention... Read More

POSTED: 12/08/2020
SOURCE: Cancer Prevention Science Blog

Portraits of Principal investigators Katherine D. Crew, M.D., M.S., (left) and Rita Kukafka, Dr.P.H., M.A. (right)

If you were concerned that you might be at increased risk for a specific kind of cancer, what would you do to confirm that risk, and what would you be willing to do to reduce that risk? The answer is likely to be, "it... Read More

POSTED: 11/19/2020
SOURCE: Cancer Prevention Science Blog

An image of a physician typing on a laptop.

In a commentary written by several of its clinical scientific leaders, changes were proposed to the National Cancer Institute (NCI) clinical trials program to improve clinical trial availability, effectiveness, and diversity... Read More

POSTED: 11/16/2020

RESEARCH UPDATE: ON THE CLINICAL FRONT A Metaproteomic Approach to Assessing Gut Microbial Protein Expression in Dietary Patterns Announcements The Transdisciplinary Research on Energetics and Cancer (TREC) Training... Read More

POSTED: 10/29/2020

An image of healthy foods, including vegetables, nuts, and eggs.

NCI Cancer Moonshotâ„  Biobank Launches Exclusively through 20 NCORP Sites

NCI has launched the Cancer Moonshotâ„  Biobank to procure and distribute longitudinal patient biospecimens for cancer research exclusively through 20 community research sites in the NCI Community Oncology Research Program (... Read More

POSTED: 10/19/2020

Photo of a cancer patient.

Projects Making Progress in Breast Cancer Detection and Prevention, By: Philip E. Castle

In the month of October, breast cancer awareness is the health message that looms large. Yet, researchers across the National Cancer Institute and across the world are focused on breast cancer all the time. In the United... Read More

POSTED: 10/19/2020
SOURCE: Cancer Prevention Science Blog

A side-by-side of two normal mammograms showing the difference between a dense breast (left) and a fatty breast (right).

The National Cancer Institute was directed by Congress "to develop, validate, improve, and implement serological testing and associated technologies" to characterize the immune responses elicited by SARS-CoV-2 viral... Read More

POSTED: 10/08/2020

NCORP Annual Meeting Focuses on Clinical Trials, COVID-19 and Telemedicine

The impact of the COVID-19 pandemic on cancer research and clinical trials, and the growing use of telemedicine garnered much of the focus during Part 1 of the annual meeting of the NCI Community Oncology Research Program (... Read More

POSTED: 09/29/2020

Screen grab of the 2020 Virtual Annual Meeting for NCORP Grantees.

Research to uncover how and why benign gynecologic conditions like endometriosis or uterine fibroids progress to invasive and deadly ovarian cancer or uterine sarcomas, is a critical and overlooked issue in women’s health. A... Read More

POSTED: 09/28/2020
SOURCE: Cancer Prevention Science Blog

An illustration of the female reproductive system.

DCP Director Philip E. Castle, Ph.D., M.P.H. Coming on board as the Division of Cancer Prevention (DCP) Director in July 2020 was a unique challenge. COVID is a serious problem now, but we have faith in science that it... Read More

POSTED: 09/11/2020

Smart Technology Is Aimed at Nutrition, Gut and Metabolism in Cancer Prevention Research Funding Opportunities

As the availability and sophistication of smart technology for health (such as wearables, sensors, and micro-robotic tools) continues to increase, these devices could prove transformative in cancer prevention. Two ongoing... Read More

POSTED: 09/08/2020
SOURCE: Cancer Prevention Science Blog

The Gut Microbiome's Important Role in Immunity

Regular Aspirin Use May Increase Older People’s Risk of Dying from Cancer

Numerous studies have suggested that people who regularly take low doses of aspirin may have reduced risks of being diagnosed with or dying from cancer. But new findings from a randomized clinical trial, called ASPREE,... Read More

POSTED: 08/18/2020
SOURCE: Cancer Currents Blog

RESEARCH UPDATE: ON THE CLINICAL FRONT Zinc Induces Potential Chemopreventive Activity in Barrett’s Esophagus Zinc’s chemopreventive activity for esophageal cancer has been well demonstrated in animal models. In humans,... Read More

POSTED: 07/30/2020

An image of different foods that are high in Zinc.

Responding to Coronavirus, Cancer Researchers Reimagine Clinical Trials

When the coronavirus pandemic reached the United States, thousands of people with cancer were participating in clinical trials, including many at St. Jude Children’s Research Hospital in Memphis, Tennessee. At St. Jude,... Read More

POSTED: 06/29/2020
SOURCE: NCI Cancer Currents Blog

A nurse at St. Jude Children's Research Hospital, checks a young boy's temperature prior to testing him for COVID-19.

NIH scientists develop blood test to help improve liver cancer screening

Scientists have developed a new test that can help identify people who are likely to develop hepatocellular carcinoma (HCC), the most common form of liver cancer. The approach uses a simple blood test to check for the... Read More

POSTED: 06/11/2020
SOURCE: NCI Press Release

Virus particles surround three human figures with their livers highlighted. One figure has a healthy liver, one has chronic liver disease and one has liver cancer.

New Technology Gives Patients Access to a 5-Minute, Office-Based Test to Identify Risk for Esophageal Cancer

A new technology coupled with a new biomarker test now in clinical trials are giving patients timely access to a quick, accurate and less invasive way to identify risk for one type of esophageal cancer. EsoCheckâ„¢ and... Read More

POSTED: 06/01/2020
SOURCE: Cancer Prevention Science Blog

How the swallowable balloon device helps detect Barrett Esophagus.

How Does COVID-19 Affect People with Cancer? NCCAPS Will Help Find Out

With the sudden explosion of the COVID-19 pandemic, we are all living with a great deal of fear, uncertainty, and anxiety. As an oncologist and cancer researcher, I know that those feelings are heightened for many people... Read More

POSTED: 05/21/2020
SOURCE: NCI Cancer Currents Blog

A nurse consults with a patient during Coronavirus quarantine.

COVID-19 is an emerging, rapidly evolving situation. In addition to the information sources listed in the web header, the National Cancer Institute and the Division of Cancer Prevention have issued guidance for DCP... Read More

POSTED: 05/07/2020

3D illustration of the novel coronavirus.

NCORP Partners in ACTIV Response to COVID-19

The National Institutes of Health and the Foundation for the NIH (FNIH) are bringing together more than a dozen leading biopharmaceutical companies, the Health and Human Services Office of the Assistant Secretary for... Read More

POSTED: 05/04/2020
SOURCE: NIH Press Release

3D illustration of the novel coronavirus.

Updated: July 9, 2020 NCI participated in the American Association for Cancer Research (AACR) Annual Meetings, held virtually on April 27 - 28, 2020 (Meeting I) and June 22 - 24, 2020 (Meeting II), including presenting the... Read More

POSTED: 04/29/2020

Logo AACR Virtual Annual Meeting I: April 27-28, 2020

RESEARCH UPDATE: ON THE CLINICAL FRONT No Association Between Vitamin D Supplementation and Risk of Colorectal Adenomas or Polyps Vitamin D has been associated with lower incidence and mortality of colorectal cancer, yet... Read More

POSTED: 04/23/2020

An open bottle of Vitamin D on a table with eggs, fish, and vegetables.

Single Dose of HPV Vaccine Yields Long-Term Protection from Many Cancer-Causing Types

More than a decade after vaccination, women who had received a single dose of human papillomavirus (HPV) vaccine continued to be protected against cervical infection with the two cancer-causing HPV types targeted by the... Read More

POSTED: 04/10/2020
SOURCE: NCI Cancer Currents Blog

A nurse administers the HPV vaccine to a participant in the NCI-funded Costa Rica HPV Vaccine Trial.