Precision cancer screening and prevention strategies: population risk, biological risk, modality, delivery
Overall, cancer death rates in the United States have been declining about 2% per year, current SEER data from 2014 through 2018 show. However, these improvements have not been experienced equally by everyone, which is one of the reasons that April is Minority Cancer Awareness Month, when we call… read more
POSTED: 04/18/2022
Joyce Ares had just turned 74 and was feeling fine when she agreed to give a blood sample for research. So she was surprised when the screening test came back positive for signs of cancer. After a repeat blood test, a PET scan and a needle biopsy, she was diagnosed with Hodgkin lymphoma.
POSTED: 04/11/2022
AACR Annual Meeting 2022
April 8-13, 2022 DCP/PREVENT-funded Project Presentations Session OPO.IM01.01 - Tumor Immunobiology 5631 - Immunomodulatory activity of sulindac plus erlotinib for colon cancer prevention in familial adenomatous polyposisPresenter/Authors Chakrapani Tripathi, Roderick H. Dashwood. Texas A&M… read more
POSTED: 04/01/2022
Screen capture of the cover of CP-CTNet March 2022 Newsletter.
Welcome to the CP-CTNet Newsletter where we share programmatic and research updates for the Cancer Prevention Clinical Trials Network (CP-CTNet).
POSTED: 03/31/2022
A group of women from diverse backgrounds.
Philadelphia, March 25, 2022 — The Tomosynthesis Mammographic Imaging Screening Trial (TMIST), is more than halfway to its recruiting goal of 128,905 participants with more than 20% of participants in the United States being Black. Recruitment of women from diverse backgrounds is vital to ensuring… read more
POSTED: 03/25/2022
An image of foods high in calcium, vitamin D, and vitamin D receptors.
This issue of Nutrition Frontiers showcases gut permeability with calcium and/or vitamin D3, microRNAs role in suppressing colitis and inflammation-associated colon cancer, and how dietary spinach reshapes gut microbiome.… read more
POSTED: 03/18/2022
An illustration displaying signal amplification.
Tumor cells release telltale molecules into blood, urine, and other bodily fluids. But it can be difficult to detect tumor-derived DNA, RNA, and proteins in the earliest stages of disease, when cancers can be easier to treat and cure. Earlier stages shed fewer cancer cells—and fewer tumor markers… read more
POSTED: 02/09/2022
Illustration showing progression from normal liver to nonalcoholic steatohepatitis.
While new cases of most cancer types have dropped over the past decade, cases of the most common type of liver cancer, hepatocellular carcinoma (HCC), are on the rise. Until recently, the main cause of HCC was hepatitis C virus infection. Although hepatitis C infection still causes many cases of… read more
POSTED: 02/04/2022
Partial screen grab of the ULACNet Zoom meeting showing a grid 9 participants.
This issue recognizes January as Cervical Cancer Awareness Month by presenting four articles entitled, "ULACNet Annual Meeting: A Global Network Together in One (Zoom) Room", "Perseverance Through the COVID… read more
POSTED: 01/28/2022
Photo of a health insurance statement.
Many people being treated for advanced cancer experience serious financial problems related to the cost of their care, even if they have health insurance, according to a new study.
POSTED: 01/26/2022
Key Messages There are many screening questions that can be addressed through clinical trials. One size doesn’t fit all: There is a trend for increasingly personalized screening, where cancer screening recommendations are guided by detailed risk assessments, including models. Promising… read more
POSTED: 01/25/2022
A meeting of statistical leads from the seven NCI Community Oncology Research Program (NCORP) Research Bases with statisticians from the Division of Cancer Prevention (DCP) Biometry Research Group took place on July 16, 2021. Meeting Goals and Content The meeting had a few key objectives: To… read more
POSTED: 01/20/2022
An illustration of a displaying a bronchoscopy, entering via nasal swabs to detect a suspicious nodule.
Lung cancer, the leading cause of cancer deaths worldwide killing 1.8 million people each year, is often diagnosed at an advanced stage when the chances for a cure are limited. In the United States, almost 60% of people diagnosed with localized lung and bronchus cancer are likely to survive for 5… read more
POSTED: 01/14/2022
Partial screen grab of the December 2021 issue of the CP-CTNet Newsletter.
Welcome to the CP-CTNet Newsletter where we share programmatic and research updates for the Cancer Prevention Clinical Trials Network (CP-CTNet).
POSTED: 12/22/2021
Thank You--50th Anniversary of the National Cancer Act
Fifty years ago this week, the National Cancer Act was signed into law, kick-starting research that has changed how cancer is prevented, detected, diagnosed, treated, and survived, and moving us closer to a time when no one… read more
POSTED: 12/20/2021
An older woman with a handful of oral medications.
For older adults undergoing treatment for advanced cancer, results from a clinical trial show that a health measurement tool called a geriatric assessment can be an important part of treatment planning. In the trial, older patients whose care was guided by a geriatric assessment were much less… read more
POSTED: 12/15/2021
Drawings of COVID-19 cells.
This issue we highlight diet quality on COVID risk and severity, along with kava’s role in lung cancer in active smokers, as well as lifelong exposure of bioactives such as ECGC and sulforaphane from green tea and broccoli… read more
POSTED: 12/01/2021
An illustration displaying possible inherited risk carriers within a family.
If your family member had cancer, would you want to know if you carried a gene mutation that increased your risk of the same cancer? This question is at the heart of three novel research projects underway to determine how best to connect with the family members of women with ovarian cancer so they… read more
POSTED: 11/29/2021
The NCI Community Oncology Research Program (NCORP) annual meeting for grantees in August 2021 virtually brought together representatives from every NCORP Research Base and Community and Minority Underserved Site to discuss… read more
POSTED: 11/10/2021
Screen capture of the Fall 2021 issue the CP-CTNet Newsletter.
The first day of autumn was September 22nd. Fall reminds us that change can be a beautiful process. It’s the season that conjures up memories of heading back to school, visits to the pumpkin patch, jumping in piles of colorful leaves, picking apples at the orchard, drinking apple cider, and making… read more
POSTED: 10/12/2021
Estimated cases of myelodysplastic syndrome cases in the US each year.
In a clinical study underway, scientists hope to unravel the complexities of a group of poorly understood and relatively rare blood disorders that often lead to cancer. In myelodysplastic syndromes (MDS), the problem arises when normal blood cells fail to function properly or are ill-formed inside… read more
POSTED: 10/05/2021
NCI graphic showing checked off text boxes
A year ago, I said that coming on board as the Division of Cancer Prevention Director in July 2020 was a “challenge,” adding that I had faith in science that the pandemic would be solved soon. Science has brought us a vaccine against SARS-CoV-2 and medicine to… read more
POSTED: 09/20/2021
In this issue, we feature: ULACNet-101 Getting Ready for Recruitment, ROCCHHA Opens Enrollment in Puerto Rico and Brazil for ULACNet-201, and an interview with Dr. Lenka Kolevic. Translations are available in Spanish and… read more
POSTED: 09/20/2021
40% of women who inherit a mutation in their BRCA1 gene will develop ovarian cancer in their lifetime.
Researchers in gynecologic oncology have begun testing a promising surgery for premenopausal women at high genetic risk for ovarian cancer that avoids early menopause and may prevent these malignancies from developing. Studies have shown that most ovarian cancers actually begin to grow from cancer… read more
POSTED: 09/07/2021
Leaders in NCI's Division of Cancer Prevention: Dr. Philip Castle, Director and Dr. Lori Minasian, Deputy Director.
This Healthcast podcast commemorates the National Cancer Act's 50th anniversary by highlighting the progress the National Cancer Institute has made in cancer prevention. Leaders in NCI's Division of Cancer Prevention talk about avoidance, screening and treatments, and vaccinations, and how… read more
POSTED: 08/31/2021