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Responding to Coronavirus, Cancer Researchers Reimagine Clinical Trials

When the coronavirus pandemic reached the United States, thousands of people with cancer were participating in clinical trials, including many at St. Jude Children’s Research Hospital in Memphis, Tennessee. At St. Jude,... Read More

POSTED: 06/29/2020
SOURCE: NCI Cancer Currents Blog

A nurse at St. Jude Children's Research Hospital, checks a young boy's temperature prior to testing him for COVID-19.

NIH scientists develop blood test to help improve liver cancer screening

Scientists have developed a new test that can help identify people who are likely to develop hepatocellular carcinoma (HCC), the most common form of liver cancer. The approach uses a simple blood test to check for the... Read More

POSTED: 06/11/2020
SOURCE: NCI Press Release

Virus particles surround three human figures with their livers highlighted. One figure has a healthy liver, one has chronic liver disease and one has liver cancer.

New Technology Gives Patients Access to a 5-Minute, Office-Based Test to Identify Risk for Esophageal Cancer

A new technology coupled with a new biomarker test now in clinical trials are giving patients timely access to a quick, accurate and less invasive way to identify risk for one type of esophageal cancer. EsoCheck™ and... Read More

POSTED: 06/01/2020
SOURCE: Cancer Prevention Science Blog

How the swallowable balloon device helps detect Barrett Esophagus.

How Does COVID-19 Affect People with Cancer? NCCAPS Will Help Find Out

With the sudden explosion of the COVID-19 pandemic, we are all living with a great deal of fear, uncertainty, and anxiety. As an oncologist and cancer researcher, I know that those feelings are heightened for many people... Read More

POSTED: 05/21/2020
SOURCE: NCI Cancer Currents Blog

A nurse consults with a patient during Coronavirus quarantine.

COVID-19 is an emerging, rapidly evolving situation. In addition to the information sources listed in the web header, the National Cancer Institute and the Division of Cancer Prevention have issued guidance for DCP... Read More

POSTED: 05/07/2020

3D illustration of the novel coronavirus.

Cancer Prevention Fellows and CPFP Staff attending the 2019 Fellows' Scientific Symposium. The annual symposium is held each fall and provides for a day of scientific exchange in the area of cancer prevention, offering the... Read More

POSTED: 05/07/2020

2019 Group photo of the CPFP Fellows.

NCORP Partners in ACTIV Response to COVID-19

The National Institutes of Health and the Foundation for the NIH (FNIH) are bringing together more than a dozen leading biopharmaceutical companies, the Health and Human Services Office of the Assistant Secretary for... Read More

POSTED: 05/04/2020
SOURCE: NIH Press Release

3D illustration of the novel coronavirus.

Updated: July 9, 2020 NCI participated in the American Association for Cancer Research (AACR) Annual Meetings, held virtually on April 27 - 28, 2020 (Meeting I) and June 22 - 24, 2020 (Meeting II), including presenting the... Read More

POSTED: 04/29/2020

Logo AACR Virtual Annual Meeting I: April 27-28, 2020

RESEARCH UPDATE: ON THE CLINICAL FRONT No Association Between Vitamin D Supplementation and Risk of Colorectal Adenomas or Polyps Vitamin D has been associated with lower incidence and mortality of colorectal cancer, yet... Read More

POSTED: 04/23/2020

An open bottle of Vitamin D on a table with eggs, fish, and vegetables.

Single Dose of HPV Vaccine Yields Long-Term Protection from Many Cancer-Causing Types

More than a decade after vaccination, women who had received a single dose of human papillomavirus (HPV) vaccine continued to be protected against cervical infection with the two cancer-causing HPV types targeted by the... Read More

POSTED: 04/10/2020
SOURCE: NCI Cancer Currents Blog

A nurse administers the HPV vaccine to a participant in the NCI-funded Costa Rica HPV Vaccine Trial.

Women Experience More Side Effects from Pelvic Radiation than Realized

Women undergoing radiation therapy for cervical or uterine cancer have a much higher incidence of serious side effects than previously realized, according to results from a new clinical trial. This information may help women... Read More

POSTED: 04/08/2020
SOURCE: NCI Cancer Currents Blog

An older woman reading a tablet.

Experimental Drug Prevents Doxorubicin from Harming the Heart

The chemotherapy drug doxorubicin is used to treat many types of cancer, but some patients who receive the drug develop heart problems. Using new insights into how doxorubicin damages the heart, researchers have identified... Read More

POSTED: 04/06/2020
SOURCE: NCI Cancer Currents Blog

An illustration displaying the experimental drug BAI1 (yellow) which inhibits the BAX protein using a novel binding site (green) and prevents the death of heart cells.

While researchers have identified some of the genetic changes that lead to cancer development, a key knowledge gap remains: finding the genetic changes that drive the development of cancers that arise at an earlier age than... Read More

POSTED: 03/05/2020
SOURCE: Cancer Prevention Science Blog

Minority Underserved NCORP Sites Taking Part in the Early Onset Malignancy Initiative

RESEARCH UPDATE: ON THE CLINICAL FRONT Genetic Variants May Partially Explain Response to Tomato Juice Intake in Men with Prostate Cancer Tomato product and lycopene intakes are associated with reduced prostate cancer risk... Read More

POSTED: 02/19/2020

Image of a man holding up a glass of tomato juice.

Cervical cancer is highly preventable, yet it is not fully prevented. Significant advancements in our understanding of the human papillomavirus (HPV)-linked development of cervical cancer have created highly effective... Read More

POSTED: 02/03/2020
SOURCE: Cancer Prevention Science Blog

Members of the US-Latin American-Caribbean Clinical Trials Network and National Cancer Institute staff.

In the path toward understanding the development and ultimate prevention of prostate cancer, researchers are studying how to keep low-grade, early stage prostate cancer being monitored on Active Surveillance from progressing... Read More

POSTED: 01/17/2020
SOURCE: Cancer Prevention Science Blog

Infographic: Percent of Prostate Cancer Cases by Stage

Division of Cancer Prevention New Grantees with Acting DCP Division Director Dr. Debbie Winn (first row center). In November 2019, the NCI Division of Cancer Prevention (DCP) for the first time held a New Grantee Workshop... Read More

POSTED: 01/14/2020

Division of Cancer Prevention New Grantees with Acting DCP Division Director Dr. Debbie Winn.

As cancer researchers delve into the many molecular processes that guide cell life within the body, NCI is looking for ways to characterize and measure different substances in this process, with an eye to identifying who has... Read More

POSTED: 12/11/2019
SOURCE: Cancer Prevention Science Blog

Parts of a cell, displaying where an extracellular viscile forming.

The National Cancer Institute (NCI) is leading a project to create a cohort of people who are newly diagnosed with diabetes in the hopes that this group, who are at increased risk of developing pancreatic cancer, provide the... Read More

POSTED: 11/19/2019
SOURCE: Cancer Prevention Science Blog

Pancreatic Cancer New Onset Diabetes: About 1 in 100 people with new onset diabetes are diagnosed with pancreatic cancer within 3 years of the diabetes diagnosis; 1 in 4 people diagnosed with pancreatic cancer were first diagnosed with diabetes.

Cancer Prevention Science editors spoke with Deborah Winn, Ph.D., acting director of the NCI Division of Cancer Prevention, about cancer prevention and early detection research in the division and beyond. Why is cancer... Read More

POSTED: 10/31/2019
SOURCE: Cancer Prevention Science Blog

Cancer prevention interventions available today include: medications, lifestyle choices, treatments for infections, screening tests, vaccines, and surgery.

RESEARCH UPDATE: ON THE CLINICAL FRONT Selectively Inhibitory Effects of Green Tea Polyphenols on Microbial Metabolism The bioavailability of green tea polyphenols (GTP) is limited and unabsorbed GTP can have bi-... Read More

POSTED: 10/23/2019

A cup of green tea.

TMIST (Tomosynthesis Mammographic Imaging Screening Trial), the large NCI screening study to learn about the best ways to find breast cancer in women who have no symptoms, is ramping up with 16,505 participants enrolled to... Read More

POSTED: 10/16/2019
SOURCE: Cancer Prevention Science Blog

Photo of Worta McCaskill-Stevens and Etta Pisano

Study Quantifies Impact of NCI-sponsored Trials on Clinical Cancer Care

A new study shows that nearly half of phase 3 cancer clinical trials carried out by the National Cancer Institute (NCI)-sponsored SWOG Cancer Research Network, one of five groups in NCI’s National Clinical Trials Network (... Read More

POSTED: 09/18/2019
SOURCE: NCI Press Release

45% of 182 Phase 3 clinical trials between 1980 and 2017 incluenced guideline care or new drug approvals.

Michigan’s Philip Stella receives NCORP 2019 Harry Hynes Award: Conversation with the Cancer Letter

Philip J. Stella, the principal investigator of the Michigan Cancer Research Consortium NCI Community Oncology Research Program site in Ann Arbor, won the 2019 Harry Hynes Award.  The award is given annually to NCORP PIs... Read More

POSTED: 09/13/2019
SOURCE: The Cancer Letter

Portrait of Philip J. Stella,  M.D.

NCI Annual Plan & Budget Proposal for Fiscal Year 2021

The year 2021 will mark the 50th anniversary of the National Cancer Act of 1971, the landmark legislation that intensified support for cancer research in the United States. The investment sparked a biomedical revolution... Read More

POSTED: 09/05/2019
SOURCE: NCI Director’s Message

Cancer Continuum: Understanding, Preventing, Detecting & Diagnosis, Treating, Advancing.