This month, the Early Detection Research Network (EDRN) marks its 20th anniversary. The National Cancer Institute (NCI) launched the network in 2000 with the goal of identifying and harnessing biomarkers as a way of detecting cancer at earlier stages. Today, the network comprises more than 300… read more
SOURCE: AACR Cancer Research Cataylst Blog
DCP Director Philip E. Castle, Ph.D., M.P.H.
As this unforgettable year of 2020 comes to an end, I am reaching the milestone of my first 6 months as Director of the NCI Division of Cancer Prevention (DCP). It has been a whirlwind of virtual meetings and… read more
SOURCE: Cancer Prevention Science Blog
The SWOG Cancer Research Network is opening to accrual the MiCHOICE Trial to study the use of decision support tools by women with high-risk breast conditions and their healthcare providers to choose among chemoprevention… read more
SOURCE: Cancer Prevention Science Blog
If you were concerned that you might be at increased risk for a specific kind of cancer, what would you do to confirm that risk, and what would you be willing to do to reduce that risk? The answer is likely to be, "it depends on your doctor."
Quotes from Focus Group Participants
"The claim of… read more
SOURCE: Cancer Prevention Science Blog
In a commentary written by several of its clinical scientific leaders, changes were proposed to the National Cancer Institute (NCI) clinical trials program to improve clinical trial availability, effectiveness, and diversity.
The article, “COVID-19, Social Justice, and Clinical Cancer Research,”… read more
SOURCE: DCP News
This issue reveals a metaproteomic approach to assessing the gut microbiome, genestein’s effect on remodeling pathways to suppress kidney cancer, and neferine from lotus seeds pro-oxidant anticancer mechanisms. Meet our… read more
SOURCE: DCP News
NCI has launched the Cancer Moonshot℠ Biobank to procure and distribute longitudinal patient biospecimens for cancer research exclusively through 20 community research sites in the NCI Community Oncology Research Program (NCORP).
Both the biobank pilot study, "NCORP Tissue Procurement Protocol: An… read more
SOURCE: NCI DCTD News
DCP Director Philip E. Castle, Ph.D., M.P.H.
In the month of October, breast cancer awareness is the health message that looms large. Yet, researchers across the National Cancer Institute and across the world are focused on breast cancer all the time. In the… read more
SOURCE: Cancer Prevention Science Blog
The National Cancer Institute was directed by Congress "to develop, validate, improve, and implement serological testing and associated technologies" to characterize the immune responses elicited by SARS-CoV-2 viral infection.
As part of the response, the institute established Serological Sciences… read more
SOURCE: DCP News
The impact of the COVID-19 pandemic on cancer research and clinical trials, and the growing use of telemedicine garnered much of the focus during Part 1 of the annual meeting of the NCI Community Oncology Research Program (NCORP) on Aug. 31. Part 2 scheduled for October 6, will focus on progress… read more
SOURCE: NCI NCORP News
Research to uncover how and why benign gynecologic conditions like endometriosis or uterine fibroids progress to invasive and deadly ovarian cancer or uterine sarcomas, is a critical and overlooked issue in women’s health.
SOURCE: Cancer Prevention Science Blog
DCP Director Philip E. Castle, Ph.D., M.P.H.
Coming on board as the Division of Cancer Prevention (DCP) Director in July 2020 was a unique challenge. COVID is a serious problem now, but we have faith in science that it will be solved soon. While cancer is not… read more
SOURCE: DCP News
As the availability and sophistication of smart technology for health (such as wearables, sensors, and micro-robotic tools) continues to increase, these devices could prove transformative in cancer prevention. Two ongoing Division of Cancer Prevention (DCP) funding opportunities are promoting the… read more
SOURCE: Cancer Prevention Science Blog
Numerous studies have suggested that people who regularly take low doses of aspirin may have reduced risks of being diagnosed with or dying from cancer. But new findings from a randomized clinical trial, called ASPREE, suggest that the same may not hold true for older adults.
The study included… read more
SOURCE: Cancer Currents Blog
This issue reveals zinc’s chemopreventive activity for Barrett’s Esophagus, the nutritional environment and intestinal stem cell’s contribution to colorectal cancer, and Sirt1 signaling in astrocytes’ contribution to… read more
SOURCE: DCP News
When the coronavirus pandemic reached the United States, thousands of people with cancer were participating in clinical trials, including many at St. Jude Children’s Research Hospital in Memphis, Tennessee.
At St. Jude, investigators took steps to reduce the risk that children participating in… read more
SOURCE: NCI Cancer Currents Blog
Scientists have developed a new test that can help identify people who are likely to develop hepatocellular carcinoma (HCC), the most common form of liver cancer. The approach uses a simple blood test to check for the patient’s previous exposure to certain viruses.
A study of the new approach was… read more
SOURCE: NCI Press Release
EsoCheck™ and EsoGuard™
NCI Annual Plan & Budget Proposal for Fiscal Year 2020 (PDF, 17.4 MB)
A new technology coupled with a new biomarker test now in clinical trials are giving patients timely access to a quick, accurate and less invasive way to… read more
SOURCE: Cancer Prevention Science Blog
With the sudden explosion of the COVID-19 pandemic, we are all living with a great deal of fear, uncertainty, and anxiety. As an oncologist and cancer researcher, I know that those feelings are heightened for many people with cancer.
SOURCE: NCI Cancer Currents Blog
COVID-19 is an emerging, rapidly evolving situation. In addition to the information sources listed in the web header, the National Cancer Institute and the Division of Cancer Prevention have issued guidance for DCP investigators during the COVID-19 pandemic. Those materials are consolidated here… read more
SOURCE: DCP News
The National Institutes of Health and the Foundation for the NIH (FNIH) are bringing together more than a dozen leading biopharmaceutical companies, the Health and Human Services Office of the Assistant Secretary for Preparedness and Response, the Centers for Disease Control and Prevention, the U.S… read more
SOURCE: NIH Press Release
Updated: July 9, 2020
NCI participated in the American Association for Cancer Research (AACR) Annual Meetings, held virtually on April 27 - 28, 2020 (Meeting I) and June 22 - 24, 2020 (Meeting II), including presenting the following research results from PREVENT and Early Phase Clinical Projects… read more
SOURCE: DCP News
This issue reveals there is no association between vitamin D supplementation and colorectal adenomas or polyps risk, that SAHA and EGCG promote apoptosis in breast cancer, and how the metabolome changes in colorectal cancer… read more
SOURCE: DCP News
More than a decade after vaccination, women who had received a single dose of human papillomavirus (HPV) vaccine continued to be protected against cervical infection with the two cancer-causing HPV types targeted by the vaccine, HPV16 and 18. The new findings are from an extended follow-up of the… read more
SOURCE: NCI Cancer Currents Blog
Women undergoing radiation therapy for cervical or uterine cancer have a much higher incidence of serious side effects than previously realized, according to results from a new clinical trial. This information may help women and their clinicians more accurately weigh the potential benefits versus… read more
SOURCE: NCI Cancer Currents Blog