Histological slide (H & E stain at x300) showing prostate cancer.
This month, the Early Detection Research Network (EDRN) marks its 20th anniversary. The National Cancer Institute (NCI) launched the network in 2000 with the goal of identifying and harnessing biomarkers as a way of detecting cancer at earlier stages. Today, the network comprises more than 300… Learn more
POSTED: 12/21/2020
DCP Director Philip E. Castle, Ph.D., M.P.H. As this unforgettable year of 2020 comes to an end, I am reaching the milestone of my first 6 months as Director of the NCI Division of Cancer Prevention (DCP). It has been a whirlwind of virtual meetings and… Learn more
POSTED: 12/17/2020
AUTHOR: Philip E. Castle, Ph.D., M.P.H.
Portraits of Principal investigators Katherine D. Crew, M.D., M.S., (left) and Rita Kukafka, Dr.P.H., M.A. (right)
The SWOG Cancer Research Network is opening to accrual the MiCHOICE Trial to study the use of decision support tools by women with high-risk breast conditions and their healthcare providers to choose among chemoprevention… Learn more
POSTED: 12/8/2020
Image of clinician's hands typing on laptop on office desk from above.
If you were concerned that you might be at increased risk for a specific kind of cancer, what would you do to confirm that risk, and what would you be willing to do to reduce that risk? The answer is likely to be, "it depends on your doctor." Quotes from Focus Group Participants "The claim of… Learn more
POSTED: 11/19/2020
AUTHOR: Goli Samimi, Ph.D., M.P.H.
In a commentary written by several of its clinical scientific leaders, changes were proposed to the National Cancer Institute (NCI) clinical trials program to improve clinical trial availability, effectiveness, and diversity. The article, “COVID-19, Social Justice, and Clinical Cancer Research,”… Learn more
POSTED: 11/16/2020
An image of healthy foods, including vegetables, nuts, and eggs.
This issue reveals a metaproteomic approach to assessing the gut microbiome, genestein’s effect on remodeling pathways to suppress kidney cancer, and neferine from lotus seeds pro-oxidant anticancer mechanisms. Meet our… Learn more
POSTED: 10/29/2020
A side-by-side of two normal mammograms showing the difference between a dense breast (left) and a fatty breast (right).
DCP Director Philip E. Castle, Ph.D., M.P.H. In the month of October, breast cancer awareness is the health message that looms large. Yet, researchers across the National Cancer Institute and across the world are focused on breast cancer all the time.… Learn more
POSTED: 10/19/2020
AUTHOR: Philip E. Castle, Ph.D., M.P.H.
Photo of a cancer patient.
NCI has launched the Cancer Moonshot℠ Biobank to procure and distribute longitudinal patient biospecimens for cancer research exclusively through 20 community research sites in the NCI Community Oncology Research Program (NCORP). Both the biobank pilot study, "NCORP Tissue Procurement Protocol: An… Learn more
POSTED: 10/19/2020
The National Cancer Institute was directed by Congress "to develop, validate, improve, and implement serological testing and associated technologies" to characterize the immune responses elicited by SARS-CoV-2 viral infection. As part of the response, the institute established Serological Sciences… Learn more
POSTED: 10/8/2020
Screen grab of the 2020 Virtual Annual Meeting for NCORP Grantees.
The impact of the COVID-19 pandemic on cancer research and clinical trials, and the growing use of telemedicine garnered much of the focus during Part 1 of the annual meeting of the NCI Community Oncology Research Program (NCORP) on Aug. 31. Part 2 scheduled for October 6, will focus on progress… Learn more
POSTED: 9/29/2020
An illustration of the female reproductive system.
Research to uncover how and why benign gynecologic conditions like endometriosis or uterine fibroids progress to invasive and deadly ovarian cancer or uterine sarcomas, is a critical and overlooked issue in women’s health.
POSTED: 9/28/2020
AUTHOR: Goli Samimi, Ph.D., M.P.H.
DCP Director Philip E. Castle, Ph.D., M.P.H. Coming on board as the Division of Cancer Prevention (DCP) Director in July 2020 was a unique challenge. COVID is a serious problem now, but we have faith in science that it will be solved soon. While cancer is… Learn more
POSTED: 9/11/2020
The Gut Microbiome's Important Role in Immunity.
As the availability and sophistication of smart technology for health (such as wearables, sensors, and micro-robotic tools) continues to increase, these devices could prove transformative in cancer prevention. Two ongoing Division of Cancer Prevention (DCP) funding opportunities are promoting the… Learn more
POSTED: 9/8/2020
Numerous studies have suggested that people who regularly take low doses of aspirin may have reduced risks of being diagnosed with or dying from cancer. But new findings from a randomized clinical trial, called ASPREE, suggest that the same may not hold true for older adults. The study… Learn more
POSTED: 8/18/2020
An image of different foods that are high in Zinc.
This issue reveals zinc’s chemopreventive activity for Barrett’s Esophagus, the nutritional environment and intestinal stem cell’s contribution to colorectal cancer, and Sirt1 signaling in astrocytes’ contribution to… Learn more
POSTED: 7/30/2020
A nurse at St. Jude Children's Research Hospital, checks a young boy's temperature prior to testing him for COVID-19.
When the coronavirus pandemic reached the United States, thousands of people with cancer were participating in clinical trials, including many at St. Jude Children’s Research Hospital in Memphis, Tennessee. At St. Jude, investigators took steps to reduce the risk that children participating in… Learn more
POSTED: 6/29/2020
Virus particles surround three human figures with their livers highlighted. One figure has a healthy liver, one has chronic liver disease and one has liver cancer.
Scientists have developed a new test that can help identify people who are likely to develop hepatocellular carcinoma (HCC), the most common form of liver cancer. The approach uses a simple blood test to check for the patient’s previous exposure to certain viruses. A study of the new approach was… Learn more
POSTED: 6/11/2020
EsoCheck and EsoGuard infographic
EsoCheck™ and EsoGuard™ NCI Annual Plan & Budget Proposal for Fiscal Year 2020 (PDF, 17.4 MB) A new technology coupled with a new biomarker test now in clinical trials are giving patients timely access to a quick, accurate and less invasive way to… Learn more
POSTED: 6/1/2020
A nurse consults with a patient during Coronavirus quarantine.
With the sudden explosion of the COVID-19 pandemic, we are all living with a great deal of fear, uncertainty, and anxiety. As an oncologist and cancer researcher, I know that those feelings are heightened for many people with cancer.
POSTED: 5/21/2020
3D illustration of the novel coronavirus.
COVID-19 is an emerging, rapidly evolving situation. In addition to the information sources listed in the web header, the National Cancer Institute and the Division of Cancer Prevention have issued guidance for DCP investigators during the COVID-19 pandemic. Those materials are consolidated here… Learn more
POSTED: 5/7/2020
3D illustration of the novel coronavirus.
The National Institutes of Health and the Foundation for the NIH (FNIH) are bringing together more than a dozen leading biopharmaceutical companies, the Health and Human Services Office of the Assistant Secretary for Preparedness and Response, the Centers for Disease Control and Prevention, the U.S… Learn more
POSTED: 5/4/2020
Logo AACR Virtual Annual Meeting I: April 27-28, 2020
Updated: July 9, 2020 NCI participated in the American Association for Cancer Research (AACR) Annual Meetings, held virtually on April 27 - 28, 2020 (Meeting I) and June 22 - 24, 2020 (Meeting II), including presenting the following research results from PREVENT and Early Phase Clinical… Learn more
POSTED: 4/29/2020
An open bottle of Vitamin D on a table with eggs, fish, and vegetables.
This issue reveals there is no association between vitamin D supplementation and colorectal adenomas or polyps risk, that SAHA and EGCG promote apoptosis in breast cancer, and how the metabolome changes in colorectal cancer… Learn more
POSTED: 4/23/2020