An MRI of a pancreas with cysts presenting.
In a new NCI-sponsored study now recruiting participants, investigators will evaluate two different screening strategies for non-cancerous pancreatic cysts to determine which works best at detecting early malignancy. Even though few of these sac-like structures are likely to develop into… Learn more
POSTED: 4/8/2021
AUTHOR: Susan Jenks
After decades of opposition to decriminalizing cannabis products (especially marijuana), a more permissive attitude toward cannabis and its derivative products has taken hold today at the state level. At the same time, inconsistencies in state policies conflict with federal law, which itself,… Learn more
POSTED: 3/8/2021
A 3D illustration of human kidneys.
This issue showcases results from the VITAL trial on vitamin D and omega-3 fatty acids on kidney function, anti-colonic inflammation properties of black raspberry, and the reversal of the Warburg effect by sulforaphane in… Learn more
POSTED: 3/3/2021
NCI 50 years graphic
For centuries, visionary physicians have stressed preventing disease as the best option. I frequently say that the “best” cancer is the cancer that never happens. Today, we turn our attentions to the scientists who made stride after stride during the last 50 years to shape cancer prevention… Learn more
POSTED: 3/1/2021
AUTHOR: Philip E. Castle, Ph.D., M.P.H.
During chemotherapy for an advanced blood cancer, Stacey Blansky vaped marijuana daily for her nausea and used cannabis oil for anxiety and stress. The decision to add these complex, plant-derived substances to ease her treatment’s side effects came after doing her own research on possible… Learn more
POSTED: 2/24/2021
Up close view of Aspirin tablets.
Millions of older Americans take aspirin daily to reduce their risk for heart disease and colorectal cancer. But, new data suggests this protective edge for colorectal cancer comes only if they begin taking aspirin before age 70. In a pooled analysis of… Learn more
POSTED: 2/11/2021
AUTHOR: Susan Jenks
Screen grab of the virtual meeting with the First Lady, Dr. Jill Biden.
Dr. Jill Biden, Ed.D., First Lady of the United States, joined NCI leaders and staff for a special virtual event marking World Cancer Day, February 4. Among the progress highlighted was the work of the NCI Community Oncology Research Program (NCORP) in bringing clinical trials to diverse… Learn more
POSTED: 2/4/2021
A meeting of 4 medical professional around a table.
The executive summary is available of an inaugural workshop to encourage and forge partnerships between oncologists, primary care providers and medical specialists to promote accrual to clinical cancer control and prevention trials conducted by the NCI Community Oncology Research Program (NCORP).
POSTED: 2/4/2021
A bottle of Naproxen placed atop a table with some tablets displayed.
An over-the-counter drug, readily available to consumers for years, may open a new option for preventing colorectal cancer in high-risk individuals. It's not the mouse that roared but the quiet mouse behind the scenes that inspired researchers to look at the anti-inflammatory drug, naproxen, said… Learn more
POSTED: 2/3/2021
AUTHOR: Susan Jenks
Histological slide (H & E stain at x300) showing prostate cancer.
This month, the Early Detection Research Network (EDRN) marks its 20th anniversary. The National Cancer Institute (NCI) launched the network in 2000 with the goal of identifying and harnessing biomarkers as a way of detecting cancer at earlier stages. Today, the network comprises more than 300… Learn more
POSTED: 12/21/2020
DCP Director Philip E. Castle, Ph.D., M.P.H. As this unforgettable year of 2020 comes to an end, I am reaching the milestone of my first 6 months as Director of the NCI Division of Cancer Prevention (DCP). It has been a whirlwind of virtual meetings and… Learn more
POSTED: 12/17/2020
AUTHOR: Philip E. Castle, Ph.D., M.P.H.
Portraits of Principal investigators Katherine D. Crew, M.D., M.S., (left) and Rita Kukafka, Dr.P.H., M.A. (right)
The SWOG Cancer Research Network is opening to accrual the MiCHOICE Trial to study the use of decision support tools by women with high-risk breast conditions and their healthcare providers to choose among chemoprevention… Learn more
POSTED: 12/8/2020
Image of clinician's hands typing on laptop on office desk from above.
If you were concerned that you might be at increased risk for a specific kind of cancer, what would you do to confirm that risk, and what would you be willing to do to reduce that risk? The answer is likely to be, "it depends on your doctor." Quotes from Focus Group Participants "The claim of… Learn more
POSTED: 11/19/2020
AUTHOR: Goli Samimi, Ph.D., M.P.H.
In a commentary written by several of its clinical scientific leaders, changes were proposed to the National Cancer Institute (NCI) clinical trials program to improve clinical trial availability, effectiveness, and diversity. The article, “COVID-19, Social Justice, and Clinical Cancer Research,”… Learn more
POSTED: 11/16/2020
An image of healthy foods, including vegetables, nuts, and eggs.
This issue reveals a metaproteomic approach to assessing the gut microbiome, genestein’s effect on remodeling pathways to suppress kidney cancer, and neferine from lotus seeds pro-oxidant anticancer mechanisms. Meet our… Learn more
POSTED: 10/29/2020
A side-by-side of two normal mammograms showing the difference between a dense breast (left) and a fatty breast (right).
DCP Director Philip E. Castle, Ph.D., M.P.H. In the month of October, breast cancer awareness is the health message that looms large. Yet, researchers across the National Cancer Institute and across the world are focused on breast cancer all the time.… Learn more
POSTED: 10/19/2020
AUTHOR: Philip E. Castle, Ph.D., M.P.H.
Photo of a cancer patient.
NCI has launched the Cancer Moonshot℠ Biobank to procure and distribute longitudinal patient biospecimens for cancer research exclusively through 20 community research sites in the NCI Community Oncology Research Program (NCORP). Both the biobank pilot study, "NCORP Tissue Procurement Protocol: An… Learn more
POSTED: 10/19/2020
The National Cancer Institute was directed by Congress "to develop, validate, improve, and implement serological testing and associated technologies" to characterize the immune responses elicited by SARS-CoV-2 viral infection. As part of the response, the institute established Serological Sciences… Learn more
POSTED: 10/8/2020
Screen grab of the 2020 Virtual Annual Meeting for NCORP Grantees.
The impact of the COVID-19 pandemic on cancer research and clinical trials, and the growing use of telemedicine garnered much of the focus during Part 1 of the annual meeting of the NCI Community Oncology Research Program (NCORP) on Aug. 31. Part 2 scheduled for October 6, will focus on progress… Learn more
POSTED: 9/29/2020
An illustration of the female reproductive system.
Research to uncover how and why benign gynecologic conditions like endometriosis or uterine fibroids progress to invasive and deadly ovarian cancer or uterine sarcomas, is a critical and overlooked issue in women’s health.
POSTED: 9/28/2020
AUTHOR: Goli Samimi, Ph.D., M.P.H.
DCP Director Philip E. Castle, Ph.D., M.P.H. Coming on board as the Division of Cancer Prevention (DCP) Director in July 2020 was a unique challenge. COVID is a serious problem now, but we have faith in science that it will be solved soon. While cancer is… Learn more
POSTED: 9/11/2020
The Gut Microbiome's Important Role in Immunity.
As the availability and sophistication of smart technology for health (such as wearables, sensors, and micro-robotic tools) continues to increase, these devices could prove transformative in cancer prevention. Two ongoing Division of Cancer Prevention (DCP) funding opportunities are promoting the… Learn more
POSTED: 9/8/2020
Numerous studies have suggested that people who regularly take low doses of aspirin may have reduced risks of being diagnosed with or dying from cancer. But new findings from a randomized clinical trial, called ASPREE, suggest that the same may not hold true for older adults. The study… Learn more
POSTED: 8/18/2020
An image of different foods that are high in Zinc.
This issue reveals zinc’s chemopreventive activity for Barrett’s Esophagus, the nutritional environment and intestinal stem cell’s contribution to colorectal cancer, and Sirt1 signaling in astrocytes’ contribution to… Learn more
POSTED: 7/30/2020
A nurse at St. Jude Children's Research Hospital, checks a young boy's temperature prior to testing him for COVID-19.
When the coronavirus pandemic reached the United States, thousands of people with cancer were participating in clinical trials, including many at St. Jude Children’s Research Hospital in Memphis, Tennessee. At St. Jude, investigators took steps to reduce the risk that children participating in… Learn more
POSTED: 6/29/2020