Topical Fluorouracil and Imiquimod in Treating Patients With High-Grade Cervical Intraepithelial Neoplasia

This early phase clinical trial studies the side effects of topical fluorouracil and
imiquimod ointment in treating patients with high-grade cervical intraepithelial neoplasia.
Topical fluorouracil may kill precancerous cells. Imiquimod ointment may stimulate the immune
system. Applying topical fluorouracil and imiquimod ointment may cause fewer side effects and
may be a better way to treat patients with precancerous cervical lesions.

Intervention

Imiquimod, Topical Fluorouracil

Condition

Cervical Intraepithelial Neoplasia Grade 2/3, Cervical Squamous Cell Carcinoma In Situ, Cervical Squamous Intraepithelial Neoplasia 2, High Grade Cervical Intraepithelial Neoplasia

Investigators

Lisa Rahangdale

See list of participating sites