PREVENT Cancer Preclinical Drug Development Program (PREVENT)

The PREVENT program is a peer-reviewed agent development program designed to support preclinical development of innovative interventions and biomarkers for cancer prevention and interception towards clinical trials. All interested researchers with novel concepts are eligible to apply. PREVENT is not a grant program, but allocates NCI contract resources and expertise to generate data and materials, which are used by the applicants for further development. PREVENT’s current research priority areas include immunoprevention, chemoprevention, and clinically translatable biomarkers.

Read more About PREVENT.

Application Instructions

Submission deadlines occur twice per year on the second Monday in January and July.

Next deadline: Monday, July 10, 2023

Instructions for Applying
Please use the latest  application template (DOCX, 32.32 KB)

Supported Projects

120 Projects from PREVENT Cycles 1 through 21: 

  • 72 Chemoprevention projects
  • 39 Immunoprevention projects
  • 9 Biomarker projects

Read more about supported projects and supported prevention approaches.

Available Resources

  • Efficacy and Intermediate Endpoint Biomarker Work
  • Toxicology and Pharmacology Testing
  • CGMP Production of Vaccines and Biologicals
  • Prime Contractors 2019–2023
  • Animal Models Used by PREVENT

View available resources

Program Administration

  • Governance Structure
  • Technology Transfer Considerations

Learn more about program administration