| Testing if High Dose Radiation Only to the Sites of Brain Cancer Compared to Whole Brain Radiation That Avoids the Hippocampus is Better at Preventing Loss of Memory and Thinking Ability |
Memantine Hydrochloride, Neurocognitive Assessment, Stereotactic Radiosurgery, Whole-Brain Radiotherapy |
Recruiting |
| Whole-Brain Radiation Therapy With or Without Hippocampal Avoidance in Treating Patients With Limited Stage or Extensive Stage Small Cell Lung Cancer |
3-Dimensional Conformal Radiation Therapy, Cognitive Assessment, Intensity-Modulated Radiation Therapy, Laboratory Biomarker Analysis, Quality-of-Life Assessment |
Active, not recruiting |
| Impact of Sentinel Lymph Node Mapping on Patient Reported Lower Extremity Limb Dysfunction in Stage I Endometrial Cancer |
Diagnostic Imaging, Indocyanine Green Solution, Minimally Invasive Surgery, Pelvic Lymphadenectomy, Questionnaire Administration, Sentinel Lymph Node Mapping |
Recruiting |
| Cognitive Training for Cancer Related Cognitive Impairment in Breast Cancer Survivors |
Arm 1: Computerized Cognitive Training-Global Stimulation Games, Arm 2: Computerized Cognitive Training-Neuroplasticity Games |
Recruiting |
| Testing an Active Form of Tamoxifen (4-hydroxytamoxifen) Delivered Through the Breast Skin to Control Ductal Carcinoma in Situ (DCIS) of the Breast |
Afimoxifene, Laboratory Biomarker Analysis, Placebo, Tamoxifen Citrate |
Recruiting |
| Diabetes Prevention Program Outcomes Study |
DPPOS Boost Lifestyle, DPPOS Group Lifestyle, Metformin, Intensive Lifestyle Group Session |
Active, not recruiting |
| The National Myelodysplastic Syndromes (MDS) Study |
Therapeutic |
Recruiting |
| Metformin Hydrochloride in Preventing Oral Cancer in Patients With an Oral Premalignant Lesion |
Laboratory Biomarker Analysis, Metformin Hydrochloride |
Active, not recruiting |
| NCI COVID-19 in Cancer Patients, NCCAPS Study |
Biospecimen Collection, Data Collection, Quality-of-Life Assessment, Questionnaire Administration |
Active, not recruiting |
| Simvastatin in Preventing Liver Cancer in Patients With Liver Cirrhosis |
Biospecimen Collection, Computed Tomography, Magnetic Resonance Imaging, Placebo Administration, Questionnaire Administration, Simvastatin |
Active, not recruiting |
| Curcumin in Preventing Gastric Cancer in Patients With Chronic Atrophic Gastritis or Gastric Intestinal Metaplasia |
Curcumin, Laboratory Biomarker Analysis, Placebo Administration, Quality-of-Life Assessment |
Active, not recruiting |
| DNA Vaccine Therapy in Treating Patients With Chronic Hepatitis C Virus Infection |
Electroporation-Mediated Plasmid DNA Vaccine Therapy, HCV DNA Vaccine INO-8000, Laboratory Biomarker Analysis, Quality-of-Life Assessment, Rocakinogene Sifuplasmid |
Active, not recruiting |
| GCC Agonist Signal in the Small Intestine |
Biopsy, Biospecimen Collection, Esophagogastroduodenoscopy, Linaclotide, Plecanatide |
Recruiting |
| Recombinant Human Papillomavirus Nonavalent Vaccine in Preventing Human Papilloma Virus in Younger Healthy Participants |
Laboratory Biomarker Analysis, Recombinant Human Papillomavirus Nonavalent Vaccine |
Active, not recruiting |
| Vaccine Therapy in Treating Patients With Newly Diagnosed Advanced Colon Polyps |
Laboratory Biomarker Analysis, MUC1 Peptide-Poly-ICLC Vaccine, Quality-of-Life Assessment, Saline |
Active, not recruiting |
| Radiation Therapy With or Without Trastuzumab in Treating Women With Ductal Carcinoma In Situ Who Have Undergone Lumpectomy |
Trastuzumab, Whole Breast Irradiation, Laboratory Biomarker Analysis |
Active, not recruiting |
| Megestrol Acetate Compared With Megestrol Acetate and Metformin to Prevent Endometrial Cancer |
Biopsy, Extended Release Metformin Hydrochloride, Megestrol Acetate, Questionnaire Administration |
Recruiting |
| Exemestane in Treating Patients With Complex Atypical Hyperplasia of the Endometrium/Endometrial Intraepithelial Neoplasia or Low Grade Endometrial Cancer |
Exemestane, Laboratory Biomarker Analysis, Pharmacokinetic Study, Questionnaire Administration |
Active, not recruiting |
| Aspirin in Preventing Colorectal Cancer in Patients With Colorectal Adenoma |
Aspirin, Biospecimen Collection, Placebo Administration, Questionnaire Administration, Rectal Biopsy |
Active, not recruiting |
| Defined Green Tea Catechin Extract in Preventing Liver Cancer in Participants With Cirrhosis |
Biopsy, Biospecimen Collection, Computed Tomography, Defined Green Tea Catechin Extract, Laboratory Biomarker Analysis, Magnetic Resonance Imaging, Pharmacological Study, Questionnaire Administration, Ultrasound |
Active, not recruiting |