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Defined Green Tea Catechin Extract in Preventing Liver Cancer in Participants With Cirrhosis

Major Program

Phase 0 I II Cancer Prevention Clinical Trials Program

Research Group

Gastrointestinal and Other Cancers

Status

Active, not recruiting

NCT ID

NCT03278925

This phase I trial studies the side effects and best dose of defined green tea catechin extract and to see how well it works in preventing liver cancer in participants with cirrhosis. Higher levels of the molecule gamma-OHPdG may be found in participants with cirrhosis, which may mean a higher risk of the development of liver cancer. Defined green tea catechin extract may work better to lower levels of gamma-OHPdG and prevent the development of liver cancer.

Intervention

Biopsy, Biospecimen Collection, Computed Tomography, Defined Green Tea Catechin Extract, Laboratory Biomarker Analysis, Magnetic Resonance Imaging, Pharmacological Study, Questionnaire Administration, Ultrasound

Condition

Cirrhosis

Investigators

Aiwu R He

See list of participating sites