Impact of Sentinel Lymph Node Mapping on Patient Reported Lower Extremity Limb Dysfunction in Stage I Endometrial Cancer

Major Program
Supportive Care and Symptom Management
NCI Community Oncology Research Program
Research Group
Community Oncology and Prevention Trials
NRG Oncology
Recruiting ID
For more information, see NCT05646316
This phase III trial compares the effect of sentinel lymph node mapping to standard lymph node dissection in reducing the risk of swelling in the legs (lymphedema) in patients undergoing a hysterectomy for stage I endometrial cancer. Standard lymph node dissection removes lymph nodes around the uterus during a hysterectomy to look for spread of cancer from the uterus to nearby lymph nodes. Sentinel lymph node mapping uses a special dye and camera to look for cancer that may have spread to nearby lymph nodes. Comparing the results of the procedures may help doctors predict the risk of long-term swelling in the legs.
Diagnostic Imaging, Indocyanine Green Solution, Minimally Invasive Surgery, Pelvic Lymphadenectomy, Questionnaire Administration, Sentinel Lymph Node Mapping
Stage I Uterine Corpus Cancer AJCC v8
Edward J Tanner, Edward J. Tanner, Tara Castellano, Nicola M. Spirtos, Joan L. Walker, Matthew T. Oliver, Kari L. Ring, Site Public Contact, Lisa M. Landrum, Kerry J. Rodabaugh, Jay W. Carlson, Robert T. Morris, Nicole P. Chappell, Gautam G. Rao, Britt K. Erickson, Jayanthi S. Lea, Emily Hinchcliff, Deric C. Savior

See list of participating sites