Major Program
Supportive Care and Symptom Management
NCI Community Oncology Research Program
Research Group
Community Oncology and Prevention Trials
Sponsor
NRG Oncology
Status
Recruiting
ClinicalTrials.gov ID
For more information, see ClinicalTrials.gov NCT05646316
This phase III trial compares the effect of sentinel lymph node mapping to standard lymph
node dissection in reducing the risk of swelling in the legs (lymphedema) in patients
undergoing a hysterectomy for stage I endometrial cancer. Standard lymph node dissection
removes lymph nodes around the uterus during a hysterectomy to look for spread of cancer from
the uterus to nearby lymph nodes. Sentinel lymph node mapping uses a special dye and camera
to look for cancer that may have spread to nearby lymph nodes. Comparing the results of the
procedures may help doctors predict the risk of long-term swelling in the legs.
node dissection in reducing the risk of swelling in the legs (lymphedema) in patients
undergoing a hysterectomy for stage I endometrial cancer. Standard lymph node dissection
removes lymph nodes around the uterus during a hysterectomy to look for spread of cancer from
the uterus to nearby lymph nodes. Sentinel lymph node mapping uses a special dye and camera
to look for cancer that may have spread to nearby lymph nodes. Comparing the results of the
procedures may help doctors predict the risk of long-term swelling in the legs.
Intervention
Sentinel Lymph Node Mapping, Questionnaire Administration, Minimally Invasive Surgery, Pelvic Lymphadenectomy, Indocyanine Green Solution
Condition
Stage I Uterine Corpus Cancer AJCC v8
Investigators
Edward J Tanner, Edward J. Tanner, Tara Castellano, Nicola M. Spirtos, Joan L. Walker, Matthew T. Oliver, Kari L. Ring