Impact of Sentinel Lymph Node Mapping on Patient Reported Lower Extremity Limb Dysfunction in Stage I Endometrial Cancer

Major Program
Supportive Care and Symptom Management
NCI Community Oncology Research Program
Research Group
Community Oncology and Prevention Trials
NRG Oncology
Recruiting ID
For more information, see NCT05646316
This phase III trial compares the effect of sentinel lymph node mapping to standard lymph
node dissection in reducing the risk of swelling in the legs (lymphedema) in patients
undergoing a hysterectomy for stage I endometrial cancer. Standard lymph node dissection
removes lymph nodes around the uterus during a hysterectomy to look for spread of cancer from
the uterus to nearby lymph nodes. Sentinel lymph node mapping uses a special dye and camera
to look for cancer that may have spread to nearby lymph nodes. Comparing the results of the
procedures may help doctors predict the risk of long-term swelling in the legs.
Sentinel Lymph Node Mapping, Questionnaire Administration, Minimally Invasive Surgery, Pelvic Lymphadenectomy, Indocyanine Green Solution
Stage I Uterine Corpus Cancer AJCC v8
Edward J Tanner, Edward J. Tanner, Tara Castellano, Nicola M. Spirtos, Joan L. Walker, Matthew T. Oliver, Kari L. Ring

See list of participating sites