| MUC1 Vaccine in Preventing Lung Cancer in Current and Former Smokers at High Risk for Lung Cancer |
MUC1 Peptide-Poly-ICLC Vaccine, Laboratory Biomarker Analysis |
Active, not recruiting |
| Testing a Combination of Vaccines for Cancer Prevention in Lynch Syndrome |
Adenovirus 5 CEA/MUC1/Brachyury Vaccine Tri-Ad5, Biopsy, Biospecimen Collection, Colonoscopy, Nogapendekin Alfa, Placebo Administration, Questionnaire Administration |
Recruiting |
| Acolbifene Versus Low Dose Tamoxifen for the Prevention of Breast Cancer in Premenopausal Women at High Risk for Development of Breast Cancer |
Biospecimen Collection, Tamoxifen, Random Periareolar Fine-Needle Aspiration, Acolbifene Hydrochloride, Mammography |
Not yet recruiting |
| Testing the Efficacy of Topical Calcipotriene Plus 5-Fluorouracil Combination to Activate the Immune System Against Precancerous Skin Lesions in Organ Transplant Recipients |
Biopsy, Calcipotriene, Fluorouracil |
Not yet recruiting |
| Testing ONC201 to Prevent Colorectal Cancer |
Biospecimen Collection, Biopsy, Colonoscopy, Sigmoidoscopy, Questionnaire Administration, Dordaviprone |
Not yet recruiting |
| Study to Determine Possible Effects of Apalutamide on EGFR Expression in Patients With Non-muscle Invasive Bladder Cancer |
Apalutamide, Biospecimen Collection, Questionnaire Administration, Transurethral Resection of Bladder Tumor |
Not yet recruiting |
| Oral Iloprost for the Prevention of Lung Cancer In Former Smokers |
Biospecimen Collection, Placebo Administration, Bronchial Brush Biopsy, Iloprost, Questionnaire Administration, Bronchoscopy |
Not yet recruiting |
| Obeticholic Acid for Prevention in Barrett's Esophagus |
Biospecimen Collection, Esophageal Biopsy, Esophagogastroduodenoscopy, Liver Ultrasonographic Elastography, Obeticholic Acid, Placebo Administration, Questionnaire Administration |
Recruiting |
| Testing RG1-VLP Vaccine to Prevent HPV-related Cancers |
Biospecimen Collection, Questionnaire Administration, HPV16 RG1 VLP Vaccine, Recombinant Human Papillomavirus Nonavalent Vaccine, Saline |
Not yet recruiting |
| Evaluation of Broccoli Seed and Sprout Extract for Detoxification of Carcinogens in Firefighters |
Biospecimen Collection, Broccoli Sprout/Broccoli Seed Extract Supplement, Placebo Administration, Questionnaire Administration, Training |
Recruiting |
| Placebo-Controlled Trial of Urolithin A Supplementation in Men With Prostate Cancer Undergoing Radical Prostatectomy, URO-PRO Trial |
Biopsy, Biospecimen Collection, Placebo Administration, Urolithin A Supplement |
Not yet recruiting |
| Finding the Best Tamoxifen Dose for Breast Cancer Risk Reduction in Premenopausal Women, RENAISSANCE Trial |
Biopsy, Biospecimen Collection, Mammography, Questionnaire Administration, Tamoxifen |
Not yet recruiting |
| Low Dose Tamoxifen With or Without Omega-3 Fatty Acids for Breast Cancer Risk Reduction |
Biospecimen Collection, Mammography, Omega-3-Acid Ethyl Esters, Questionnaire Administration, Random Periareolar Fine-Needle Aspiration, Tamoxifen |
Not yet recruiting |
| The National Myelodysplastic Syndromes (MDS) Study |
Therapeutic |
Recruiting |
| Diabetes Prevention Program Outcomes Study |
DPPOS Boost Lifestyle, DPPOS Group Lifestyle, Metformin, Intensive Lifestyle Group Session |
Active, not recruiting |
| Testing an Active Form of Tamoxifen (4-hydroxytamoxifen) Delivered Through the Breast Skin to Control Ductal Carcinoma in Situ (DCIS) of the Breast |
Afimoxifene, Laboratory Biomarker Analysis, Placebo, Tamoxifen Citrate |
Recruiting |
| Five or Ten Year Colonoscopy for 1-2 Non-Advanced Adenomatous Polyps |
5-year and 10 Year Surveillance Colonoscopy after Qualifying Colonoscopy |
Recruiting |
| A Study to Compare Two Surgical Procedures in Individuals With BRCA1 Mutations to Assess Reduced Risk of Ovarian Cancer |
Bilateral Salpingectomy, Bilateral Salpingectomy with Oophorectomy, Biospecimen Collection, Quality-of-Life Assessment, Questionnaire Administration, Transvaginal Ultrasound |
Recruiting |
| Increasing the Dose of Survivorship Care Planning in Improving Care and Outcomes in Prostate Cancer Survivors Receiving Androgen Deprivation Therapy |
Questionnaire Administration, Survivorship Care Plan (SCP), Treatment Plan |
Active, not recruiting |
| Testing if High Dose Radiation Only to the Sites of Brain Cancer Compared to Whole Brain Radiation That Avoids the Hippocampus is Better at Preventing Loss of Memory and Thinking Ability |
Memantine Hydrochloride, Neurocognitive Assessment, Stereotactic Radiosurgery, Whole-Brain Radiotherapy |
Recruiting |