Major Program
NCI Community Oncology Research Program
Research Group
Community Oncology and Prevention Trials
Sponsor
NRG Oncology
Status
Recruiting
ClinicalTrials.gov ID
For more information, see ClinicalTrials.gov NCT04251052
This clinical trial evaluates how well two surgical procedures (bilateral salpingectomy and bilateral salpingo-oophorectomy) work in reducing the risk of ovarian cancer for individuals with BRCA1 mutations. Bilateral salpingectomy involves the surgical removal of fallopian tubes, and bilateral salpingo-oophorectomy involves the surgical removal of both the fallopian tubes and ovaries. This study may help doctors determine if the two surgical procedures are nearly the same for ovarian cancer risk reduction for women with BRCA1 mutations.
Intervention
Bilateral Salpingectomy, Bilateral Salpingectomy with Oophorectomy, Biospecimen Collection, Quality-of-Life Assessment, Questionnaire Administration, Transvaginal Ultrasound, Ultrasound Imaging
Condition
Ovarian Carcinoma
Investigators
Kathryn P. Pennington, Kathryn P Pennington, Gregory A. Masters, Georgina Cheng, Shannon MacLaughlan, Samir D. Undevia, Gustavo C. Rodriguez, John M. Schallenkamp, Nicola M. Spirtos, Eugenia Girda, Carolyn Y. Muller, Jeffrey W. Elder, Kari L. Ring, Matthew L. Ryan, Lisa M. Barroilhet, William H. Bradley, Charles A. Leath, Ramey D. Littell, Beth Y. Karlan, Guilherme Henrique C. Cantuaria, Emma Barber, Kathryn A. Mills, David P. Bender, Leslie S. Bradford, Dana Zakalik, Ira S. Winer, Kathleen J. Yost, Gretchen E. Glaser, Bryan A. Faller, Jay W. Carlson, Brent J. Tierney, Kerry J. Rodabaugh, Kara C. Long Roche, Richard G. Moore, Michael G. Kelly, Mariam M. AlHilli, Joan L. Walker, Mark S. Shahin, Carlton L. Schwab, Setsuko K. Chambers, Scott E. Lentz, Lindsay Brubaker, Pamela J. Stone, Joyce Varughese, Koji Matsuo, Lee-May Chen, Linus T. Chuang, Beverly Long, Sharad A. Ghamande, Sarah E. Gill, Raanan Alter, Dana M. Roque, Andrea R. Hagemann, Marina Frimer, Marina Stasenko, Stephanie V. Blank, Jason D. Wright, Kevin Holcomb, Mary J. Cunningham, Kimberly E. Resnick, Sarah H. Kim, Gina M. Mantia Smaldone, Alaina J. Brown, Claire Hoppenot, Krista S. Pfaendler, Elmer G. Lehman, Matthew P. Schlumbrecht, Tashanna K. Myers, Kathryn Maurer, Marguerite (Meg) L. Palisoul, Deanna G. Teoh, Ismail Mert, Robert Neff, Georgia A. McCann, Stephen H. Bush, Hui Chen, Shahzad Siddique, Nicole P. Chappell, Susan C. Modesitt, Tara Castellano, Angeles A. Secord, Bethany Bustamante, Maria C. Bell, Rebecca D. Kaltman, Site Public Contact, Jessica Jou, Bobbie J. Rimel, Kathleen G. Essel, David P. Warshal, Dong Hoon Suh, Yong-Man Kim, Jessica A. Thomes Pepin, Edward C. Grendys, Summer B. Dewdney, Allison R. Wagreich, Sudarshan K. Sharma, Mihae Song, Gabrielle Gossner, Julia Fehniger, Katherine Miller, Elise J. Simons, David A. Iglesias, Emese Zsiros, Hope Cottrill, Hyun Jin Choi, Andrea D. Jewell, Christopher Tarney, Jae-Hoon Kim, Jovana Y. Martin, Sarah M. Crafton, Janice S. Kwon, Dan S. Zuckerman, Elizabeth R. Burton, Timothy R. Wassenaar, Jami A. Fukui, Monica H. Vetter, Barbara S. Norquist, Andrew S. Kennedy, Jessica E. Parker, Michael S. Guy, Gloria S. Huang, Shaina Bruce, Maureen R. Hewitt, Amanda L. Jackson, Chelsea Salyer