‘CASCADE’ Network Organizational Units

The ‘CASCADE’ Network consists of the following organizational units: one Network Coordinating Center (supported via RFA-CA-21-045), three Research Bases (supported via RFA-CA-21-046), and nine Clinical Sites (three sites supported via RFA-CA-21-047; six additional sites supported via RFA-CA-22-051).

Organizational Unit

Principal Investigator(s)


Grant No.

CASCADE Network Coordinating Center (CNCC)

Suzanne Siminski, M.S., M.B.A., and KyungMann Kim, Ph.D.

Frontier Science, with
University of Wisconsin


Research Base 1 (RB1)

Rachel Winer, Ph.D., M.P.H. and
Elizabeth Brown, Sc.D., M.S.

University of Washington, with
Fred Hutchinson Cancer Research Center


Research Base 2 (RB2)

Timothy Wilkin, M.D., M.P.H., Anna Giuliano, Ph.D., and
Carla Chibwesha, M.D., M.Sc.

Weill Medical College of Cornell University, with Moffitt Cancer Center and University of North Carolina at Chapel Hill


Research Base 3 (RB3)

Jennifer Smith, Ph.D., M.P.H., Michael Hudgens, Ph.D., and Lameck Chinula, M.D., M.P.H.

University of North Carolina at Chapel Hill


Clinical Trials Site 1 (CS1): Uganda

Betty Mwesigwa, M.B.Ch.B., M.Sc.

Makerere University Walter Reed Project, with US Military HIV Research Program and Uganda Cancer Institute


Clinical Trials Site 2 (CS2): Kenya

Michael Chung, M.D., Ph.D., M.P.H. and Samah Sakr, M.B.Ch.B.

Emory University, with Coptic Hope Center for Infectious Diseases and Kenyatta National Hospital


Clinical Trials Site 3 (CS3): Botswana

Scott Dryden-Peterson, M.D., M.S. and Doreen Ramogola-Masire, M.B.B.S., Ph.D., M.P.H.

Brigham and Women's Hospital, with Botswana Harvard AIDS Institute Partnership


Clinical Trials Site 4 (CS4): US/Georgia

Lisa Flowers, M.D., M.P.H. and

Anandi Sheth, M.D., M.Sc.


Emory University


Clinical Trials Site 5 (CS5): Rwanda

Gad Murenzi, M.D., M.S., Kathryn Anastos, M.D., and Rubagumya Fidel, M.D., M.P.H.


Research for Development, Albert Einstein College of Medicine, with Rwanda Military Hospital


Clinical Trials Site 6 (CS6): Kenya

Nelly Mugo, M.B.Ch.B., M.P.H., and Kenneth Ngure, Ph.D., M.P.H., M.Sc.


Kenya Medical Research Institute (KEMRI), with Jomo Kenyatta University of Agriculture and Technology


Clinical Trials Site 7 (CS7): Zimbabwe

Chirenje Zvavahera, M.D., and Bothwell Guzha, M.B.Ch.B, M.Phil


University of California, San Francisco, with University of Zimbabwe


Clinical Trials Site 8 (CS8): US/Maryland

Clement Adebamowo, B.M.Ch.B., Sc.D., and Gregory Taylor, M.D.


University of Maryland, Baltimore


Clinical Trials Site 9 (CS9): South Africa

Nivashnee Naicker, M.D., M.P.H, M.A.S.

Centre for the AIDS Programme of Research in South Africa (CAPRISA)