About CIP-Net

The Cancer Immunoprevention Network (CIP-Net) overall research objectives are as follows:

  • Discover novel immunoprevention pathways and targets
  • Elucidate immune responses to the earliest stages of carcinogenesis
  • Preclinical development and testing of interventions (agents/vaccines)
  • Investigate mechanisms of efficacy and potential side-effects of precision cancer prevention-interception strategies
  • Immunoprevention models development and optimization
  • Immune mechanisms of preventive cancer vaccines and immunomodulatory agents
A graph displaying microsatellite instability detected by fragment analysis in fecal DNA samples.
Microsatellite instability detected by fragment analysis in fecal DNA samples. Blue: fecal samples from mismatch repair-deficient tumor-bearing animals; Pink or green: wild type control.
Organoids generated from mismatch repair-deficient mouse intestinal tumors.
Organoids generated from mismatch repair-deficient mouse intestinal tumors.