Aspirin and Zileuton and Biomarker Expression in Nasal Tissue of Current Smokers

Major Program
Phase 0 I II Cancer Prevention Clinical Trials Program
Research Group
Lung and Upper Aerodigestive Cancer
Sponsor
National Cancer Institute (NCI)
Status
Completed
ClinicalTrials.gov ID
For more information, see ClinicalTrials.gov NCT02348203
This randomized phase II trial studies the effects of aspirin and zileuton on genes related to tobacco use in current smokers. Aspirin and zileuton may interfere with genes related to tobacco use and may be useful in preventing lung cancer in current smokers.
Intervention
Aspirin, Laboratory Biomarker Analysis, Zileuton, Placebo Administration
Condition
Tobacco Use Disorder
Investigators
Linda L Garland

See list of participating sites