Aspirin and Zileuton and Biomarker Expression in Nasal Tissue of Current Smokers

Major Program(s) or Research Group(s)

  • Lung and Upper Aerodigestive Cancer
  • Phase 0/I/II Cancer Prevention Clinical Trials Program

Sponsor

National Cancer Institute (NCI)

Status

Active, not recruiting

ClinicalTrials.gov ID

For more information, see ClinicalTrials.gov NCT02348203

This randomized phase II trial studies the effects of aspirin and zileuton on genes related
to tobacco use in current smokers. Aspirin and zileuton may interfere with genes related to
tobacco use and may be useful in preventing lung cancer in current smokers.

Intervention

Aspirin, Laboratory Biomarker Analysis, Zileuton, Placebo Administration

Condition

Tobacco Use Disorder

Investigators

Linda L Garland

See list of participating sites