Aspirin and Zileuton and Biomarker Expression in Nasal Tissue of Current Smokers

This randomized phase II trial studies the effects of aspirin and zileuton on genes related to tobacco use in current smokers. Aspirin and zileuton may interfere with genes related to tobacco use and may be useful in preventing lung cancer in current smokers.

Intervention

Aspirin, Laboratory Biomarker Analysis, Placebo, Zileuton

Condition

Current Every Day Smoker, Multiple Pulmonary Nodules, Tobacco Smoking, Tobacco Use Disorder

Investigators

Linda L. Garland, Jun Yan, Avrum Spira

See list of participating sites