The Supportive Care and Symptom Management program supports studies on the prevention or treatment of acute and chronic symptoms and morbidities related to cancer and its treatment. This includes the impact on the quality of life of patients and their informal caregivers. The program also supports studies of patients and their caregivers at the end of life.
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About Supportive Care and Symptom Management
The program supports research in three areas: prevention or treatment of acute or chronic symptoms and morbidities related to cancer, its treatment and caregiving (symptom management research); effects on quality of life from cancer, its treatment and caregiving (quality of life research); and end-of-life psychosocial issues, caregiving and treatment strategies (end-of-life research).
Through the NCI Community Oncology Research Program (NCORP), clinical trials are underway to evaluate therapies to prevent or ameliorate a broad range of symptoms and/or toxicities associated with cancer its treatment and caregiving. Other studies funded separately are investigating a range of treatment effects on health-related quality of life and a variety of influences on the end-of-life cancer experience.
Topic Areas include: Anorexia, Cachexia, Cardiotoxicity, Caregiver Issues, Cognitive Dysfunction, Distress/Anxiety/Depression, End of Life, Fatigue, Geriatrics, Hot Flashes, Lymphedema, Medication Adherence, Mucositis, Multiple Symptoms, Musculoskeletal Symptoms, Nausea, Neuropathy, Nutrition, Oral Complications, Other Supportive Care Issues, Pain, Palliative Care, Pediatrics/Adolescents/Young Adult, Physical Functioning, Quality of Life, Skin Toxicities, Sleep Disorders, and Urinary Complications.
Selected Topics
- HEAL Initiative
- Patient Resources on Side Effects of Cancer Treatment
- Patient Resources on Coping with Cancer
Resources
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Building Bridges in Cancer Symptom Science Webinar SeriesThis series is aimed at bringing together interdisciplinary researchers in cancer symptom science to share their expertise and further discussions in the field.
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DCP Early Career Scientist Spotlight Research Seminar SeriesThis seminar series highlights nominated early career scientists who are advancing research within the areas supported by DCP.
Funding Opportunities
No matching Funding Opportunities were found.
Grantee Details
Clinical Trials
| Title | Intervention | Sponsor Sort descending | Status |
|---|---|---|---|
| Effects of Dexrazoxane Hydrochloride on Biomarkers Associated With Cardiomyopathy and Heart Failure After Cancer Treatment | Assessment of Therapy Complications, Laboratory Biomarker Analysis, Quality-of-Life Assessment, Questionnaire Administration | Children's Oncology Group | Recruiting |
| Genetic Analysis in Identifying Late-Occurring Complications in Childhood Cancer Survivors | Laboratory Biomarker Analysis, Questionnaire Administration | Children's Oncology Group | Active, not recruiting |
| Neuropsychological and Behavioral Testing in Younger Patients With Cancer | Cognitive Assessment, Quality-of-Life Assessment | Children's Oncology Group | Active, not recruiting |
| A Study of the Drug Letermovir as Prevention of Cytomegalovirus Infection After Stem Cell Transplant in Pediatric Patients | Biospecimen Collection, Letermovir | Children's Oncology Group | Recruiting |
| Studying the Effect of Levocarnitine in Protecting the Liver From Chemotherapy for Leukemia or Lymphoma | Biospecimen Collection, Calaspargase Pegol, Levocarnitine, Pegaspargase, Quality-of-Life Assessment | Children's Oncology Group | Recruiting |
| A Study to Learn More About the Health of Persons With Down Syndrome After Treatment for Acute Leukemia | Biospecimen Collection, Clinical Evaluation, Neurocognitive Assessment, Questionnaire Administration, Survey Administration | Children's Oncology Group | Recruiting |
| A Study About How Blood Cell Growth Patterns Relate to Heart Health After Treatment for Hodgkin Lymphoma | Archive Sample Retrieval, Biospecimen Collection, Electronic Health Record Review, Magnetic Resonance Imaging, Survey Administration | Children's Oncology Group | Recruiting |
| A Culturally-Tailored Mobile Health and Social Media Physical Activity Intervention for Improving Physical Activity in Hispanic or Latino/Latina Adolescent and Young Adult Childhood Cancer Survivors, Walking Juntos Study | Discussion, Goal Setting, Interview, Media Intervention, Medical Device Usage and Evaluation, Questionnaire Administration, Reward, Text Message-Based Navigation Intervention | Children's Oncology Group | Recruiting |
| Triptorelin for the Prevention of Ovarian Damage in Adolescents and Young Adults With Cancer | Best Practice, Biospecimen Collection, Electronic Health Record Review, Survey Administration, Triptorelin Pamoate | Children's Oncology Group | Recruiting |
| Xylitol Dental Wipes for the Reduction of Bloodstream Infection Risk in Children With Acute Myeloid Leukemia | Best Practice, Biospecimen Collection, Cytarabine, Electronic Health Record Review, Placebo Administration, Xylitol-containing Oral Wipe | Children's Oncology Group | Not yet recruiting |
News and Events
Predicting and Mitigating Nausea and Vomiting
Date Posted: August 22, 2025
Diet and Nutrition for Managing Cancer Symptoms
Date Posted: May 27, 2025
Targeting Aging Biology to Optimize the Long-Term Health of Cancer Survivors
Date Posted: May 15, 2025
Harnessing Studies of Diet and the Gut Microbiome to Reduce Colorectal Cancer Burden
Date Posted: April 29, 2025