Effects of Dexrazoxane Hydrochloride on Biomarkers Associated With Cardiomyopathy and Heart Failure After Cancer Treatment

This clinical trial studies the effects of dexrazoxane hydrochloride on biomarkers associated
with cardiomyopathy and heart failure after cancer treatment. Studying samples of blood in
the laboratory from patients receiving dexrazoxane hydrochloride may help doctors learn more
about the effects of dexrazoxane hydrochloride on cells. It may also help doctors understand
how well patients respond to treatment.

Intervention

Assessment of Therapy Complications, Laboratory Biomarker Analysis, Quality-of-Life Assessment, Questionnaire Administration

Condition

Hodgkin Lymphoma in Remission, Leukemia in Remission, Lymphoblastic Lymphoma, Osteosarcoma, Recurrent Leukemia, Recurrent Lymphoma, Recurrent Malignant Neoplasm

Investigators

Eric J Chow, Douglas J. Scothorn, Jennifer J. Greene Welch, Craig Lotterman, Steven J. Kuerbitz, Jennifer L. Reichek, Sharon B. Abish, Douglas S. Hawkins, Anne-Marie R. Langevin, Richard L. Tower, David L. Becton, Lillian R. Meacham, Narayana Gowda, Nina S. Kadan-Lottick, William D. Roberts, Rebecca E. McFall, Kenneth J. Cohen, Julienne Brackett, Madhu S. Gowda, Daniel C. Bowers, Nichole L. Bryant, Yvan Samson, Rene Y. McNall-Knapp, Emad K. Salman, Michael B. Harris, Jonathan D. Fish, Susan J. Lindemulder, Thomas B. Russell, Philip M. Monteleone, Janice F. Olson, Lynda M. Vrooman, Adonis N. Lorenzana, Eric C. Larsen, Laura E. Hogan, Bruno Michon, Wade T. Kyono, Douglas R. Strother, Jessica L. Heath, John F. Kuttesch, Saro H. Armenian, Judy L. Felgenhauer, Jason M. Fixler, Gregory E. Halligan, Angela R. Girvin, Marianne B. Phillips, Jacqueline M. Kraveka, Rajaram Nagarajan, Jaime M. Libes, Laura A. Campbell, Luis A. Clavell, Alan K. Ikeda, Jay Michael S. Balagtas, Dana A. Obzut, Alexandra M. Walsh, Ramamoorthy Nagasubramanian, Holly E. Pariury, Smita Bhatia, Anderson (Andy) B. Collier, Robert J. Hayashi

See list of participating sites