Genetic Analysis in Identifying Late-Occurring Complications in Childhood Cancer Survivors

Major Program
Supportive Care and Symptom Management
Research Group
Community Oncology and Prevention Trials
Sponsor
Children's Oncology Group
Status
Recruiting
ClinicalTrials.gov ID
For more information, see ClinicalTrials.gov NCT00082745
This clinical trial studies cancer survivors to identify those who are at increased risk of developing late-occurring complications after undergoing treatment for childhood cancer. A patient's genes may affect the risk of developing complications, such as congestive heart failure, avascular necrosis, stroke, and second cancer, years after undergoing cancer treatment. Genetic studies may help doctors identify survivors of childhood cancer who are more likely to develop late complications.
Intervention
Questionnaire Administration, Laboratory Biomarker Analysis
Condition
Childhood Malignant Neoplasm
Investigators
Smita Bhatia, Vlad C. Radulescu, Vonda L. Crouse, Nichole L. Bryant, Nicholas W. McGregor, Eric J. Lowe, Doured Daghistani, Paul D. Harker-Murray, ZoAnn E. Dreyer, Michael K. Richards, Yvan Samson, Fataneh (Fae) Majlessipour, Ashok B. Raj, Alissa Kahn, Christopher Mpofu, Rajaram Nagarajan, Mariko Sato, Gail C. Megason, Emad K. Salman, Lolie C. Yu, Stuart L. Cramer, Tanya R. Brown, Nibal A. Zaghloul, Thomas W. McLean, Denise A. Rokitka, Nadine P. SantaCruz, William A. May, Sandeep Batra, Joseph P. Neglia, Mariana P. Silva, Adonis N. Lorenzana, Danielle N. Friedman, Samuel O. Anim, Ramamoorthy Nagasubramanian, Arthur K. Ritchey, Stanton C. Goldman, Robert J. Hayashi, Jessica L. Heath, Jordan R. Hansford, Maria L. Kirby, Wade T. Kyono, Marianne B. Phillips, Catherine A. Long, Lillian R. Meacham, Kenneth B. De Santes, Rene Y. McNall-Knapp, Mark A. Ranalli, Jay Michael S. Balagtas, Mark E. Weinblatt, Helen Irving, Dana A. Obzut, Felipe S. Bautista-Otanez, Uma H. Athale, Michael S. Isakoff, Mandy M. Atkinson, Ayman A. El-Sheikh, Nkechi I. Mba, Leo Mascarenhas, Kathleen J. Yost, Carola A. Arndt, Philip M. Monteleone, David L. Becton, Michael B. Harris, Debra L. Friedman, Donna L. Johnston, Patrick J. Leavey, Jaime M. Libes, Saro H. Armenian, William D. Roberts, Eugenia Chang, Paul C. Nathan, Conrad V. Fernandez, Jeffrey S. Dome, Janice F. Olson, Shayna M. Zelcer, Rebecca E. McFall, Keith J. August, Judy L. Felgenhauer, Bassem I. Razzouk, Lars M. Wagner, Carla B. Golden, Sarah J. McKillop, Rama Jasty, Nina S. Kadan-Lottick, Laura A. Campbell, Colleen H. McDonough, Mary L. Schmidt, Melissa M. Hudson, Alan K. Ikeda, Site Public Contact

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