A Study to Learn More About the Health of Persons With Down Syndrome After Treatment for Acute Leukemia

Major Program
Supportive Care and Symptom Management
NCI Community Oncology Research Program
Research Group
Community Oncology and Prevention Trials
Children's Oncology Group
ClinicalTrials.gov ID
For more information, see ClinicalTrials.gov NCT05702645
This study attempts to learn more about the health of persons with Down syndrome after treatment for acute leukemia. Children with Down syndrome are at increased risk for side effects during treatment for acute leukemia, but it is unclear of their risk for long-term effects of cancer treatment. By learning more about the factors that may contribute to chronic health conditions and long-term effects after treatment for leukemia in persons with Down syndrome, clinical practice guidelines for survivorship care can be developed to help improve their quality-of-life.
Biospecimen Collection, Clinical Evaluation, Questionnaire Administration, Survey Administration
B Acute Lymphoblastic Leukemia Associated With Down Syndrome, Down Syndrome, Myeloid Leukemia Associated With Down Syndrome
Maria M Gramatges, Susan E. Spiller, Jean M. Tersak, Site Public Contact, Lauren R. Weintraub, Rene Y. McNall-Knapp, Karen S. Fernandez, Emad K. Salman, Judy L. Felgenhauer, Joshua W. Goldman, Jennifer J. Welch, Jon M. Brandt, Ramamoorthy Nagasubramanian, Najat C. Daw, Mukund G. Dole, Susan J. Lindemulder, Anya Levinson, Ksenya Shliakhtsitsava, Don E. Eslin, Thomas W. McLean, Alan K. Ikeda, Samuel J. Milanovich, Robert J. Hayashi, Shannon M. Cohn, Karen E. Effinger, Aniket Saha, Kayelyn J. Wagner, Jennifer G. Michlitsch, Alice Lee, Donald T. Beam

See list of participating sites