Skip to main content
An official website of the United States government

Supportive Care and Symptom Management

The Supportive Care and Symptom Management program supports studies on the prevention or treatment of acute and chronic symptoms and morbidities related to cancer and its treatment. This includes the impact on the quality of life of patients and their informal caregivers. The program also supports studies of patients and their caregivers at the end of life.

On This Page

  • All Heading 2s will automatically be pulled in to this list.
  • Do not edit the content on this template.

About Supportive Care and Symptom Management

The program supports research in three areas: prevention or treatment of acute or chronic symptoms and morbidities related to cancer, its treatment and caregiving (symptom management research); effects on quality of life from cancer, its treatment and caregiving (quality of life research); and end-of-life psychosocial issues, caregiving and treatment strategies (end-of-life research).

Through the NCI Community Oncology Research Program (NCORP), clinical trials are underway to evaluate therapies to prevent or ameliorate a broad range of symptoms and/or toxicities associated with cancer its treatment and caregiving. Other studies funded separately are investigating a range of treatment effects on health-related quality of life and a variety of influences on the end-of-life cancer experience. 

Topic Areas include: Anorexia, Cachexia, Cardiotoxicity, Caregiver Issues, Cognitive Dysfunction, Distress/Anxiety/Depression, End of Life, Fatigue, Geriatrics, Hot Flashes, Lymphedema, Medication Adherence, Mucositis, Multiple Symptoms, Musculoskeletal Symptoms, Nausea, Neuropathy, Nutrition, Oral Complications, Other Supportive Care Issues, Pain, Palliative Care, Pediatrics/Adolescents/Young Adult, Physical Functioning, Quality of Life, Skin Toxicities, Sleep Disorders, and Urinary Complications.

Selected Topics

Funding Opportunities

No matching Funding Opportunities were found.

View All Funding Opportunities

Grantee Details

PI Name Sort descending PI Organization Title Grant Number Program Official
Cao, Weidan

Ohio State University
United States

Treatment-Related Cardiotoxicity Risk Prediction for Breast Cancer Patients with a Multimodal AI-based System 1R01CA301579-01 Eileen Dimond, R.N., M.S.
Cao, Weidan

Ohio State University
United States

Treatment-Related Cardiotoxicity Risk Prediction for Breast Cancer Patients with a Multimodal AI-based System 1R01CA301579-01 Eileen Dimond, R.N., M.S.
Cao, Yin

Washington University
United States

PROSPECT-Global Consortium and Risk Factor Discovery 3OT2CA297576-01S1 Asad Umar, D.V.M., Ph.D.
Carlson, Jay W

Ozark Health Ventures, Llc
United States

Ozark Health Ventures LLC dba Cancer Research for the Ozarks (CRO) 3UG1CA189822-11S1 Vanessa A. White, M.P.H.
Carlson, Jay W

Ozark Health Ventures, Llc
United States

Ozark Health Ventures LLC dba Cancer Research for the Ozarks (CRO) 3UG1CA189822-11S1 Vanessa A. White, M.P.H.
Carson, Tiffany Lashaun

H. Lee Moffitt Cancer Ctr & Res Inst
United States

Determining the structural- and functional-level effects of diet-specific interventions on the gut microbiota of a diverse sample of Southern United States adults 5R01CA253219-06 Young Kim, Ph.D.
Castilla, Lucio H.

Univ Of Massachusetts Med Sch Worcester
United States

Study of tyrosine kinase inhibitors as preventive therapy in RUNX1-FPD 1U01CA296350-01 Marjorie Perloff, M.D.
Castro, Cesar M

Massachusetts General Hospital
United States

Composing CODAs to cervical cancer screening through an integrated CRISPR and fluorescent nucleic acid approach 3U01CA279858-03S2 Christos Patriotis, Ph.D., M.Sc.
Caulin, Carlos

University Of Arizona
United States

Genetic Alterations That Confer High Risk to Oral Premalignant Lesions 5R01CA274857-04
Caywood, Emi H

Nemours Children'S Hospital, Delaware
United States

Nemours NCI Community Oncology Research Program (NCORP) 3UG1CA189958-11S1 Vanessa A. White, M.P.H.
Caywood, Emi H

Nemours Children'S Hospital, Delaware
United States

Nemours NCI Community Oncology Research Program (NCORP) 3UG1CA189958-11S1 Vanessa A. White, M.P.H.
Chak, Amitabh

Case Western Reserve University
United States

Pathways of Injury and Repair in Barrett's Carcinogenesis 5P01CA269019-03 Asad Umar, D.V.M., Ph.D.
Chan, Andrew T

Massachusetts General Hospital
United States

MGH- PROSPECT: Pathways, Risk factors, and mOleculeS to Prevent Early-onset Colorectal Tumors 3OT2CA297680-01S1 Asad Umar, D.V.M., Ph.D.
Chan, Alexandre

University Of California-Irvine
United States

Neurotrophic strategy to mitigate chemotherapy-related brain injury 5R01CA276212-03 John Clifford, Ph.D.
Chan, Alexandre

University Of California-Irvine
United States

Neurotrophic strategy to mitigate chemotherapy-related brain injury 5R01CA276212-03 John Clifford, Ph.D.

Clinical Trials

Status
Title Sort descending Intervention Sponsor Status
Methylphenidate and Exercise in Reducing Cancer-Related Fatigue in Patients With Prostate Cancer Exercise Intervention, Methylphenidate, Placebo, Quality-of-Life Assessment, Questionnaire Administration, Stretching M.D. Anderson Cancer Center Active, not recruiting
Mobile Health and Social Media Physical Activity Intervention Among Adolescent and Young Adult Childhood Cancer Survivors, the StepByStep Study Educational Intervention, FitBit, Goal Setting, Health Promotion and Education, Media Intervention, Telephone-Based Intervention Children's Oncology Group Active, not recruiting
Mobile Health for Adherence in Breast Cancer Patients Electronic Health Record Review, Health Promotion and Education, Health Telemonitoring, Interview, Patient Navigation, Survey Administration, Text Message-Based Navigation Intervention ECOG-ACRIN Cancer Research Group Recruiting
Monitoring Symptoms to Help Young Women Take Hormone Therapy for Stage I-III Breast Cancer, ASPEN Study Best Practice, Biospecimen Collection, Endocrine Drug Therapy, Health Education, Questionnaire Administration, Symptom Specific Assessment Tool SWOG Cancer Research Network Active, not recruiting
Mosaic Trial for Stem Cell Transplant Recipients Enhanced Usual Care (Control) Website, Intervention website Northwestern University Recruiting
Myopenia and Mechanisms of Chemotherapy Toxicity in Older Adults With Colorectal Cancer Wake Forest University Health Sciences Recruiting
Naloxegol in Treating Patients With Stage IIIB-IV Non-small Cell Lung Cancer Naloxegol, Placebo, Laboratory Biomarker Analysis, Quality-of-Life Assessment Alliance for Clinical Trials in Oncology Active, not recruiting
Neuropsychological and Behavioral Testing in Younger Patients With Cancer Cognitive Assessment, Quality-of-Life Assessment Children's Oncology Group Active, not recruiting
New Assessment System in Measuring Symptom Distress in Cancer Patients Interview, Quality-of-Life Assessment, Questionnaire Administration M.D. Anderson Cancer Center Recruiting
Nutrition Therapy in Improving Immune System in Patients With Bladder Cancer That Can Be Removed by Surgery Laboratory Biomarker Analysis, Nutritional Intervention, Placebo Administration, Quality-of-Life Assessment, Questionnaire Administration SWOG Cancer Research Network Active, not recruiting