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Supportive Care and Symptom Management

The Supportive Care and Symptom Management program supports studies on the prevention or treatment of acute and chronic symptoms and morbidities related to cancer and its treatment. This includes the impact on the quality of life of patients and their informal caregivers. The program also supports studies of patients and their caregivers at the end of life.

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About Supportive Care and Symptom Management

The program supports research in three areas: prevention or treatment of acute or chronic symptoms and morbidities related to cancer, its treatment and caregiving (symptom management research); effects on quality of life from cancer, its treatment and caregiving (quality of life research); and end-of-life psychosocial issues, caregiving and treatment strategies (end-of-life research).

Through the NCI Community Oncology Research Program (NCORP), clinical trials are underway to evaluate therapies to prevent or ameliorate a broad range of symptoms and/or toxicities associated with cancer its treatment and caregiving. Other studies funded separately are investigating a range of treatment effects on health-related quality of life and a variety of influences on the end-of-life cancer experience. 

Topic Areas include: Anorexia, Cachexia, Cardiotoxicity, Caregiver Issues, Cognitive Dysfunction, Distress/Anxiety/Depression, End of Life, Fatigue, Geriatrics, Hot Flashes, Lymphedema, Medication Adherence, Mucositis, Multiple Symptoms, Musculoskeletal Symptoms, Nausea, Neuropathy, Nutrition, Oral Complications, Other Supportive Care Issues, Pain, Palliative Care, Pediatrics/Adolescents/Young Adult, Physical Functioning, Quality of Life, Skin Toxicities, Sleep Disorders, and Urinary Complications.

Selected Topics

Funding Opportunities

No matching Funding Opportunities were found.

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Grantee Details

PI Name Sort descending PI Organization Title Grant Number Program Official
Bryan, Angela

University Of Colorado
United States

Cannabis for Palliative Care in Cancer: A Placebo-controlled Randomized Trial of Full Spectrum Hemp-derived CBD/THC 5R01CA284860-03 Brennan Streck, Ph.D., RN, M.P.H.
Bryan, Angela

University Of Colorado
United States

Cannabis for Palliative Care in Cancer: A Placebo-controlled Randomized Trial of Full Spectrum Hemp-derived CBD/THC 5R01CA284860-03 Brennan Streck, Ph.D., RN, M.P.H.
Buczynski, Matthew Wallace

Virginia Polytechnic Inst And St Univ
United States

Anti-nociceptive actions of CART II in chemotherapy-induced peripheral neuropathy 5R01CA284075-03 Rachel Altshuler, Ph.D.
Buczynski, Matthew Wallace

Virginia Polytechnic Inst And St Univ
United States

Anti-nociceptive actions of CART II in chemotherapy-induced peripheral neuropathy 5R01CA284075-03 Rachel Altshuler, Ph.D.
Buis, Lorraine R

University Of Michigan At Ann Arbor
United States

MyGI Diet for Colorectal Cancer Prevention 5R01CA255743-04 Nancy J. Emenaker, Ph.D., RDN, LD, FAND
Burgess, Mark Thomas

Sloan-Kettering Inst Can Research
United States

Clinical assessment of radiotherapy-induced vaginal toxicity with multiparametric ultrasound imaging 5R21CA290252-02 Goli Samimi, Ph.D., M.P.H.
Buszczak, Michael

Ut Southwestern Medical Center
United States

Developing ribosome biogenesis inhibitors for the prevention of cancer 5UG3CA290312-02 Kajal Biswas, Ph.D.
Butler, Kathleen Yost

Corewell Health
United States

Cancer Research Consortium of West Michigan (CRCWM) 3UG1CA189860-11S1 Vanessa A. White, M.P.H.
Butler, Kathleen Yost

Corewell Health
United States

Cancer Research Consortium of West Michigan (CRCWM) 3UG1CA189860-11S1 Vanessa A. White, M.P.H.
Butryn, Meghan

Drexel University
United States

Efficacy of a multi-level intervention designed to promote adherence to WCRF/AICR dietary guidelines for cancer prevention 1R01CA288323-01A1 Nancy J. Emenaker, Ph.D., RDN, LD, FAND
Cai, Long

California Institute Of Technology
United States

Understanding the role of tumor microenvironment in low grade glioma progression to malignancy 4U01CA294551-02 Sidney Fu, M.D.
Cantuaria, Guilherme

Northside Hospital Atlanta
United States

Georgia NCI Community Oncology Research Program (GA NCORP) 3UG1CA189997-11S1 Vanessa A. White, M.P.H.
Cantuaria, Guilherme

Northside Hospital Atlanta
United States

Georgia NCI Community Oncology Research Program (GA NCORP) 3UG1CA189997-11S1 Vanessa A. White, M.P.H.
Cao, Yin

Washington University
United States

Obesity, sedentary behaviors, and diet quality for prevention and early detection of early-onset colorectal neoplasia 4R37CA246175-06 Asad Umar, D.V.M., Ph.D.
Cao, Shugeng

University Of Hawaii At Hilo
United States

Discovery of novel natural TEAD inhibitors for the chemoprevention of liver tumors 5UG3CA290375-02 Altaf Mohammed, Ph.D.

Clinical Trials

Status
Title Sort descending Intervention Sponsor Status
Increasing Patients' Engagement in Breast Cancer Surgery Decision-Making Usual Care, Web-based decision aid Alliance for Clinical Trials in Oncology Active, not recruiting
Infliximab and Intravenous Immunoglobulin Therapy in Treating Patients With Steroid-Refractory Pneumonitis Infliximab, Intravenous Immunoglobulin Therapy, Prednisone, Quality-of-Life Assessment, Questionnaire Administration ECOG-ACRIN Cancer Research Group Active, not recruiting
IVIG for Infection Prevention After CAR-T-Cell Therapy Anti-CD19 CAR T Cells Preparation, Biospecimen Collection, Electronic Health Record Review, Immune Globulin Infusion (Human), 10% Solution, Saline, Survey Administration Fred Hutchinson Cancer Center Recruiting
Lactobacillus Plantarum in Preventing Acute Graft Versus Host Disease in Children Undergoing Donor Stem Cell Transplant Allogeneic Hematopoietic Stem Cell Transplantation, Lactobacillus plantarum strain 299, Lactobacillus plantarum strain 299v, Placebo Administration Children's Oncology Group Active, not recruiting
Lanreotide Versus Placebo Before Surgery to Prevent a Surgical Complication Called a Pancreatic Fistula Biospecimen Collection, Distal Pancreatectomy, Lanreotide, Questionnaire Administration, Saline SWOG Cancer Research Network Recruiting
Late Effects After Treatment in Patients With Previously Diagnosed High-Risk Neuroblastoma Cytology Specimen Collection Procedure, Laboratory Biomarker Analysis, Quality-of-Life Assessment Children's Oncology Group Active, not recruiting
Learning Collaborative Versus Technical Assistance in Delivering a Palliative Care Program to Patients With Advanced Cancer and Their Caregivers Behavioral, Psychological or Informational Intervention, Educational Intervention, Medical Examination Assessment, Quality-of-Life Assessment, Survey Administration, Telephone-Based Intervention University of Rochester NCORP Research Base Active, not recruiting
Manual Therapy in Treating Fibrosis-Related Late Effect Dysphagia in Head and Neck Cancer Survivors Manual Therapy M.D. Anderson Cancer Center Active, not recruiting
Meaning-Centered Counseling for Chinese Patients Who Are Being Treated for Advanced Cancer Adaptation of IMCP for Chinese Immigrant Cancer Patients, In-depth Patient Interviews, Individual Meaning-Centered Psychotherapy for Chinese (IMCP-Ch) (For Phase 3 and Phase 4) Memorial Sloan Kettering Cancer Center Recruiting
Metformin Hydrochloride in Preventing Breast Cancer in Patients With Atypical Hyperplasia or In Situ Breast Cancer metformin hydrochloride, placebo Alliance for Clinical Trials in Oncology Active, not recruiting