https://prevention.cancer.gov

The Supportive Care and Symptom Management program supports studies on the prevention or treatment of acute and chronic symptoms and morbidities related to cancer and its treatment. This includes the impact on the quality of life of patients and their informal caregivers. The program also supports studies of patients and their caregivers at the end of life.

About Supportive Care and Symptom Management

The program supports research in three areas: prevention or treatment of acute or chronic symptoms and morbidities related to cancer, its treatment and caregiving (symptom management research); effects on quality of life from cancer, its treatment and caregiving (quality of life research); and end-of-life psychosocial issues, caregiving and treatment strategies (end-of-life research).

Through the NCI Community Oncology Research Program (NCORP), clinical trials are underway to evaluate therapies to prevent or ameliorate a broad range of symptoms and/or toxicities associated with cancer its treatment and caregiving. Other studies funded separately are investigating a range of treatment effects on health-related quality of life and a variety of influences on the end-of-life cancer experience.

Topic Areas include: Anorexia, Cachexia, Cardiotoxicity, Caregiver Issues, Cognitive Dysfunction, Distress/Anxiety/Depression, End of Life, Fatigue, Geriatrics, Hot Flashes, Lymphedema, Medication Adherence, Mucositis, Multiple Symptoms, Musculoskeletal Symptoms, Nausea, Neuropathy, Nutrition, Oral Complications, Other Supportive Care Issues, Pain, Palliative Care, Pediatrics/Adolescents/Young Adult, Physical Functioning, Quality of Life, Skin Toxicities, Sleep Disorders, and Urinary Complications.

Selected Topics

Resources

Funding Opportunities

No matching Funding Opportunities were found.

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Grantee Details

PI Name Sort descending	PI Organization	Title	Grant Number	Program Official
Wright, Alexi A	Dana-Farber Cancer Inst United States	Randomized trial of REVITALIZE: A telehealth intervention to reduce fatigue interference among adults with advanced ovarian cancer on PARP inhibitors	5R01CA289547-02	Goli Samimi, Ph.D., M.P.H.
Xu, Xiangxi Mike	University Of Miami School Of Medicine United States	Countering microtubule stabilization within hair follicles in ovarian cancer chemotherapy	5R01CA286527-02	Rachel Altshuler, Ph.D.
Yang, Qing	University Of Texas Med Br Galveston United States	The role of acute excitation of sensory neurons in the development of paclitaxel-induced peripheral neuropathy	5R01CA273001-02	Rachel Altshuler, Ph.D.
Yu, Anthony Francis	Sloan-Kettering Inst Can Research United States	Intensive Blood Pressure Control During Cardiotoxic Breast Cancer Treatment (PROTECT) Trial	5R37CA273923-03	Eileen Dimond, R.N., M.S.
Zheng, Qin	Johns Hopkins University United States	Determining the function of medium to large diameter sensory neurons in paclitaxel-induced pain via large-scale in vivo DRG imaging	1R01CA291906-01A1	Rachel Altshuler, Ph.D.

Clinical Trials

Title Sort descending	Intervention	Sponsor	Status
Surgical Thromboprophylaxis Practices in Oncology Patients Within the NCORP Network, STOP-VTE Study	Non-Interventional Study	Wake Forest University Health Sciences	Recruiting
Taxane and Taxane-Induced Peripheral Neuropathy in African American Patients With Stage I-III Breast Cancer	Docetaxel, Paclitaxel, Quality-of-Life Assessment, Questionnaire Administration	ECOG-ACRIN Cancer Research Group	Active, not recruiting
Telephone Support in Advanced Gastrointestinal Cancer	Acceptance and Commitment Therapy, Education/Support	Indiana University	Recruiting
Testing if High Dose Radiation Only to the Sites of Brain Cancer Compared to Whole Brain Radiation That Avoids the Hippocampus is Better at Preventing Loss of Memory and Thinking Ability	Biospecimen Collection, Magnetic Resonance Imaging, Memantine Hydrochloride, Neurocognitive Assessment, Stereotactic Radiosurgery, Survey Administration, Whole-Brain Radiotherapy	NRG Oncology	Recruiting
Testing Laser Therapy for Treatment of Vaginal Dryness in Survivors of Breast Cancer, The Revitalize Trial	Laser Therapy, Quality of Life Assessment, Questionnaire Administration, Sham Intervention	Alliance for Clinical Trials in Oncology	Recruiting
Testing the Addition of the Drug BMX-001, a Radioprotector, or a Placebo to the Usual Chemoradiation Therapy for Patients With Head and Neck Cancer	Best Practice, Biospecimen Collection, Cisplatin, Computed Tomography, Image Guided Radiation Therapy, Intensity-Modulated Radiation Therapy, Magnetic Resonance Imaging, MnSOD Mimetic BMX-001, Placebo Administration, Questionnaire Administration	NRG Oncology	Recruiting
Testing the Application of Mepitel Film During Radiation Therapy to Reduce Radiation Related Redness and Peeling in Breast Cancer Patients Following Mastectomy	Best Practice, Quality-of-Life Assessment, Questionnaire Administration, Wound Dressing Material	Alliance for Clinical Trials in Oncology	Active, not recruiting
Testing the Effects of Exercise on Chemotherapy-Induced Peripheral Neuropathy	Best Practice, Exercise Counseling, Exercise Intervention, Magnetic Resonance Imaging, Neuropathy Assessment, Questionnaire Administration	University of Rochester NCORP Research Base	Active, not recruiting
Testing the Effects of MK-3475 (Pembrolizumab) With or Without the Usual Chemotherapy Treatment for Patients 70 Years of Age and Older With Advanced Non-small Cell Lung Cancer	Carboplatin, Comprehensive Geriatric Assessment, Pembrolizumab, Pemetrexed, Quality-of-Life Assessment, Questionnaire Administration	Alliance for Clinical Trials in Oncology	Active, not recruiting
The Effect of Yoga on Nerve Pain Caused by Chemotherapy (Chemotherapy-Induced Peripheral Neuropathy)	Education control, Usual care, Yoga	Dana-Farber Cancer Institute	Active, not recruiting