This phase III trial compares the effects of olanzapine versus megestrol acetate in treating
loss of appetite in patients with cancer that has spread to other places in the body
(advanced). Olanzapine may stimulate and increase appetite. This study aims to find out if
olanzapine is better than the usual approach (megestrol acetate) for stimulating appetite and
preventing weight loss.
Intervention
Megestrol Acetate, Olanzapine, Questionnaire Administration
Condition
Advanced Malignant Solid Neoplasm, Anorexia, Hematopoietic and Lymphoid Cell Neoplasm
Investigators
Aminah Jatoi, MD, Debra M. Prow, Bryan A. Faller, Kendrith M. Rowland, Deborah W. Wilbur, Joshua Lukenbill, Grant R. Seeger, Ki Y. Chung, Nicholas DiBella, Isoken Koko, Richard L. Deming, Tareq Al Baghdadi, Preston D. Steen, Jay W. Carlson