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Supportive Care and Symptom Management

The Supportive Care and Symptom Management program supports studies on the prevention or treatment of acute and chronic symptoms and morbidities related to cancer and its treatment. This includes the impact on the quality of life of patients and their informal caregivers. The program also supports studies of patients and their caregivers at the end of life.

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About Supportive Care and Symptom Management

The program supports research in three areas: prevention or treatment of acute or chronic symptoms and morbidities related to cancer, its treatment and caregiving (symptom management research); effects on quality of life from cancer, its treatment and caregiving (quality of life research); and end-of-life psychosocial issues, caregiving and treatment strategies (end-of-life research).

Through the NCI Community Oncology Research Program (NCORP), clinical trials are underway to evaluate therapies to prevent or ameliorate a broad range of symptoms and/or toxicities associated with cancer its treatment and caregiving. Other studies funded separately are investigating a range of treatment effects on health-related quality of life and a variety of influences on the end-of-life cancer experience. 

Topic Areas include: Anorexia, Cachexia, Cardiotoxicity, Caregiver Issues, Cognitive Dysfunction, Distress/Anxiety/Depression, End of Life, Fatigue, Geriatrics, Hot Flashes, Lymphedema, Medication Adherence, Mucositis, Multiple Symptoms, Musculoskeletal Symptoms, Nausea, Neuropathy, Nutrition, Oral Complications, Other Supportive Care Issues, Pain, Palliative Care, Pediatrics/Adolescents/Young Adult, Physical Functioning, Quality of Life, Skin Toxicities, Sleep Disorders, and Urinary Complications.

Selected Topics

Resources

Funding Opportunities

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Grantee Details

PI Name PI Organization Title Grant Number Program Official
Johnson, Constance Margaret

University Of Texas Hlth Sci Ctr Houston
United States

Auricular Point Acupressure to Manage Chemotherapy Induced Neuropathy 3R01CA245054-05S1 Rachel Altshuler, Ph.D.
Melemedjian, Ohannes Kevork

University Of Maryland Baltimore
United States

Identification of novel targets for the treatment of chemotherapy-induced painful peripheral neuropathy 4R01CA249939-02 Rachel Altshuler, Ph.D.
Brown, Austin L

Baylor College Of Medicine
United States

A Systems Epidemiology Approach for Predicting Methotrexate Neurotoxicity in Pediatric Acute Leukemia 5R01CA272981-03 Rachel Altshuler, Ph.D.
Mclouth, Laurie

University Of Kentucky
United States

Pathways, a Hope-Based Intervention to Support Personal Goal Pursuit, Mental Health, and Quality of Life during Advanced Lung Cancer Treatment 5R01CA283929-03 Brennan Streck, Ph.D., RN, M.P.H.
Damaj, M. Imad

Virginia Commonwealth University
United States

Targeting Sphingosine-1-phosphate (S1P1) receptors for the treatment of Aromatase Inhibitors-induced Musculoskeletal Symptoms 5R01CA272147-03 Rachel Altshuler, Ph.D.
Fuschiotti, Patrizia

University Of Pittsburgh At Pittsburgh
United States

Develop IL13Ra1 for diagnosis of early-stage mycosis fungoides 5R21CA280445-02 Wendy Wang, Ph.D., M.Sc.
Phillips, Nicholas S

St. Jude Children'S Research Hospital
United States

Cardiopulmonary function and cerebral blood flow in Hodgkin Lymphoma survivors 5R21CA280230-02 Eileen Dimond, R.N., M.S.
Staff, Nathan P

Mayo Clinic Rochester
United States

Investigating the role of MAP2 in chemotherapy-induced peripheral neurotoxicity 5R01CA275870-03 Rachel Altshuler, Ph.D.
Garcia, Jose M.

Seattle Inst For Biomedical/Clinical Res
United States

SArcopenia in Men with Prostate Cancer undergoing ADT (SAP-ADT) 5R01CA279220-02 Marjorie Perloff, M.D.
Mehrara, Babak J

Sloan-Kettering Inst Can Research
United States

Mechanisms of racial disparity in breast cancer-related lymphedema 5R01CA278599-03
Deng, Gary E

University Of California-Irvine
United States

Acupuncture to Improve Outcomes in Patients with Sepsis: a Randomized Controlled Trial 7R21CA286330-03 Goli Samimi, Ph.D., M.P.H.
Pozdeyev, Nikita

University Of Colorado Denver
United States

Genetic architecture of thyroid cancer and its clinical utility 5R21CA282380-02 Wendy Wang, Ph.D., M.Sc.
Webster, Nicholas J

Veterans Medical Research Fdn/San Diego
United States

The Effect of Time-Restricted Eating on the Efficiency of Chemo- and Hormonal-Therapy in Breast Cancer 5R21CA288777-02 Nancy J. Emenaker, Ph.D., RDN, LD, FAND
Lee, Richard T

Beckman Research Institute/City Of Hope
United States

A Pilot Study to Evaluate the Benefits of Phytocannabinoids for the Treatment of Chronic Chemotherapy-Induced Peripheral Neuropathy 1R21CA260447-01A1 Rachel Altshuler, Ph.D.
Xu, Xiangxi Mike

University Of Miami School Of Medicine
United States

Countering microtubule stabilization within hair follicles in ovarian cancer chemotherapy 5R01CA286527-02 Rachel Altshuler, Ph.D.

Clinical Trials

Status
Title Sort descending Intervention Sponsor Status
Comparing Brief Behavioral Therapy (BBT-CI) and Healthy Eating Education Learning (HEAL) for Cancer-Related Sleep Problems While Receiving Cancer Treatment Behavioral Intervention, Electronic Health Record Review, Quality-of-Life Assessment, Questionnaire Administration University of Rochester NCORP Research Base Recruiting
Comparing Cooling and/or Compression Approaches of Limbs for Prevention of Chemotherapy-Induced Peripheral Neuropathy Biospecimen Collection, Cryocompression Therapy, Pneumatic Compression Therapy, Quality-of-Life Assessment, Questionnaire Administration SWOG Cancer Research Network Recruiting
Comparing Single vs Multiple Dose Radiation for Cancer Patients With Brain Metastasis and Receiving Immunotherapy fractionated stereotactic radiosurgery (FSRS), single fraction stereotactic radiosurgery (SSRS) Wake Forest University Health Sciences Recruiting
Comparing Telephone Symptom Monitoring Interventions for Managing Symptoms and Psychological Distress During Oral Anti-Cancer Treatment Counseling, Health Education, Interview, Medical Chart Review, Monitoring, Questionnaire Administration NRG Oncology Recruiting
Computer Training Program for Younger Patients With a Brain Tumor Who Underwent Radiation Therapy Cognitive Assessment, Computer-Assisted Cognitive Training, Psychosocial Assessment and Care, Quality-of-Life Assessment, Questionnaire Administration Children's Oncology Group Active, not recruiting
Controlled Trial Of Acupuncture To Prevent Radiation-Induced Xerostomia Acupuncture - Group 1, Acupuncture - Group 2, Questionnaire, Standard Care M.D. Anderson Cancer Center Active, not recruiting
Cost Communication and Financial Navigation in Cancer Patients (COSTCOM) Best Practice, Financial Navigation, Interview, Survey Administration ECOG-ACRIN Cancer Research Group Recruiting
Developing an Internet-Delivered Sexual Health Program for Breast Cancer Survivors, SHINE Trial Internet-based Intervention Wake Forest University Health Sciences Active, not recruiting
Dexamethasone in Controlling Dyspnea in Patients With Cancer Dexamethasone, Questionnaire Administration, Placebo M.D. Anderson Cancer Center Active, not recruiting
Distance-Based Exercise to Preserve Function and Prevent Disability Accelerometry, Aerobic Exercise Intervention, Dumbbell Exercise Intervention, Electronic Health Record Review, Exercise intervention, Interview, Questionnaire Administration, Telemedicine Alliance for Clinical Trials in Oncology Not yet recruiting