Skip to main content
An official website of the United States government

Supportive Care and Symptom Management

The Supportive Care and Symptom Management program supports studies on the prevention or treatment of acute and chronic symptoms and morbidities related to cancer and its treatment. This includes the impact on the quality of life of patients and their informal caregivers. The program also supports studies of patients and their caregivers at the end of life.

On This Page

  • All Heading 2s will automatically be pulled in to this list.
  • Do not edit the content on this template.

About Supportive Care and Symptom Management

The program supports research in three areas: prevention or treatment of acute or chronic symptoms and morbidities related to cancer, its treatment and caregiving (symptom management research); effects on quality of life from cancer, its treatment and caregiving (quality of life research); and end-of-life psychosocial issues, caregiving and treatment strategies (end-of-life research).

Through the NCI Community Oncology Research Program (NCORP), clinical trials are underway to evaluate therapies to prevent or ameliorate a broad range of symptoms and/or toxicities associated with cancer its treatment and caregiving. Other studies funded separately are investigating a range of treatment effects on health-related quality of life and a variety of influences on the end-of-life cancer experience. 

Topic Areas include: Anorexia, Cachexia, Cardiotoxicity, Caregiver Issues, Cognitive Dysfunction, Distress/Anxiety/Depression, End of Life, Fatigue, Geriatrics, Hot Flashes, Lymphedema, Medication Adherence, Mucositis, Multiple Symptoms, Musculoskeletal Symptoms, Nausea, Neuropathy, Nutrition, Oral Complications, Other Supportive Care Issues, Pain, Palliative Care, Pediatrics/Adolescents/Young Adult, Physical Functioning, Quality of Life, Skin Toxicities, Sleep Disorders, and Urinary Complications.

Selected Topics

Resources

Funding Opportunities

No matching Funding Opportunities were found.

View All Funding Opportunities

Grantee Details

PI Name PI Organization Title Sort descending Grant Number Program Official
Johnson, Constance Margaret

University Of Texas Hlth Sci Ctr Houston
United States

Auricular Point Acupressure to Manage Chemotherapy Induced Neuropathy 3R01CA245054-05S1 Rachel Altshuler, Ph.D.
Prigerson, Holly Gwen

Weill Medical Coll Of Cornell Univ
United States

Behavioral and Psychosocial Effects on Study Outcomes in End-Stage Cancer Treatment (BEST End-Stage Cancer Study) 5R35CA197730-11 Brennan Streck, Ph.D., RN, M.P.H.
Veiseh, Omid

Rice University
United States

Bioengineered lymphatic regenerating platform for treatment of breast cancer related lymphedema 1R01HL179534-01 Goli Samimi, Ph.D., M.P.H.
Delaney, Joe R

Medical University Of South Carolina
United States

Biologic rationale of fallopian tube removal to prevent uterine serous carcinoma 1R21CA292343-01A1 Goli Samimi, Ph.D., M.P.H.
Chong, Catherine Daniela

Mayo Clinic Arizona
United States

Biomarker Signature to Predict the Persistence of Post-Traumatic Headache 5R33NS113315-03 Brandy Heckman-Stoddard, Ph.D., M.P.H.
Lindau, Stacy Tessler

University Of Chicago
United States

Bionic Breast Project: A Neuroprosthesis to Restore Touch Sensation and Reduce Chronic Pain After Mastectomy 5R01CA281301-03 Marjorie Perloff, M.D.
Im, Eun-Ok

University Of Texas At Austin
United States

Cancer Pain Management: A Technology-Based Intervention for Asian American Breast Cancer Survivors 5R33CA280979-04 Brennan Streck, Ph.D., RN, M.P.H.
Bryan, Angela

University Of Colorado
United States

Cannabis for Palliative Care in Cancer: A Placebo-controlled Randomized Trial of Full Spectrum Hemp-derived CBD/THC 5R01CA284860-03 Brennan Streck, Ph.D., RN, M.P.H.
Meghani, Salimah H.

University Of Pennsylvania
United States

Cannabis use and outcomes in ambulatory patients with cancer: A 12-month cohort study 3R01CA270483-04S1 Gabriela Riscuta, M.D., CNS
Phillips, Nicholas S

St. Jude Children'S Research Hospital
United States

Cardiopulmonary function and cerebral blood flow in Hodgkin Lymphoma survivors 5R21CA280230-02 Eileen Dimond, R.N., M.S.
Pyter, Leah M

Ohio State University
United States

Chemotherapy-induced circadian master clock disruptions and fatigue 5R01CA270372-04 Marjorie Perloff, M.D.
Mahan, Kristin Eckel

University Of Texas Hlth Sci Ctr Houston
United States

Circadian regulation of astrocytic adenosine kinase in the irradiated and cancer brain 1R21CA292148-01 John Clifford, Ph.D.
Groninger, J. Hunter

Medstar Health Research Institute
United States

Cognitive behavioral theory-assisted virtual reality for chronic cancer pain (VR-CAN): device prototype development and feasibility testing 1R21CA299799-01 Brennan Streck, Ph.D., RN, M.P.H.
Ah, Diane Marie Von

Ohio State University
United States

Cognitive Training for Cancer-related Cognitive Impairment: A Multi-Center Randomized Controlled Trial 5R01CA276222-04 Brandy Heckman-Stoddard, Ph.D., M.P.H.
Kahalley, Lisa Schum

Baylor College Of Medicine
United States

Comparison of Symptom Burden/Toxicity, Neurocognitive Change, and Functional Outcomes in Pediatric Brain Tumor Patients Treated with Proton vs. Photon Radiotherapy. 3R01CA249988-05S3 Rachel Altshuler, Ph.D.

Clinical Trials

Status
Title Intervention Sponsor Status
Additional Support Program Via Text Messaging and Telephone-Based Counseling for Breast Cancer Patients Receiving Hormonal Therapy Best Practice, Educational Intervention, Motivational Interviewing, Quality-of-Life Assessment, Questionnaire Administration, Text Message-based Navigation Intervention Alliance for Clinical Trials in Oncology Active, not recruiting
An Internet-based Program to Help Cancer Survivors Manage Pain Internet-based pain coping skills program Wake Forest University Health Sciences Recruiting
Assessing Benefits and Harms of Cannabis/Cannabinoid Use Among Cancer Patients Treated in Community Oncology Clinics Non-interventional Study Wake Forest University Health Sciences Recruiting
Assessing Compliance With Mercaptopurine Treatment in Younger Patients With Acute Lymphoblastic Leukemia in First Remission Behavioral Intervention, Compliance Monitoring, Laboratory Biomarker Analysis, Mercaptopurine, Questionnaire Administration, Standard Follow-Up Care Children's Oncology Group Active, not recruiting
Assessment of Cognitive Function in Breast Cancer and Lymphoma Patients Receiving Chemotherapy University of Rochester NCORP Research Base Enrolling by invitation
Axillary Reverse Mapping in Preventing Lymphedema in Patients With Breast Cancer Undergoing Axillary Lymph Node Dissection Axillary Lymph Node Dissection, Isosulfan Blue, Mapping, Quality-of-Life Assessment, Questionnaire Administration Alliance for Clinical Trials in Oncology Active, not recruiting
Bupropion to Reduce Cancer Related Fatigue in Cancer Survivors Biospecimen Collection, Bupropion Hydrochloride Controlled-release, Placebo Administration, Quality-of-Life Assessment, Questionnaire Administration University of Rochester NCORP Research Base Active, not recruiting
Cancer and Blood Pressure Management, CARISMA Study Best Practice, Blood Pressure Measurement, Clinical Management, Quality-of-Life Assessment, Questionnaire Administration ECOG-ACRIN Cancer Research Group Active, not recruiting
Cognitive Training for Cancer Related Cognitive Impairment in Breast Cancer Survivors Arm 1: Computerized Cognitive Training-Global Stimulation Games, Arm 2: Computerized Cognitive Training-Neuroplasticity Games NRG Oncology Recruiting
Communication About Sexual Health in Gynecologic Cancer Sexual Health Resources, Starting the Conversation Fox Chase Cancer Center Recruiting