Bupropion in Reducing Cancer Related Fatigue in Stage I-III Breast Cancer Survivors

This phase III trial studies how well bupropion works in reducing cancer related fatigue in
stage I-III breast cancer survivors. Bupropion is a drug that is used to treat depression, as
well as to help people quit smoking. Cancer and its treatment can cause fatigue. Giving
bupropion may improve cancer related fatigue in breast cancer survivors.

Intervention

Bupropion Hydrochloride Controlled-release, Placebo, Quality-of-Life Assessment, Questionnaire Administration

Condition

Anatomic Stage I Breast Cancer AJCC v8, Anatomic Stage IA Breast Cancer AJCC v8, Anatomic Stage IB Breast Cancer AJCC v8, Anatomic Stage II Breast Cancer AJCC v8, Anatomic Stage IIA Breast Cancer AJCC v8, Anatomic Stage IIB Breast Cancer AJCC v8, Anatomic Stage III Breast Cancer AJCC v8, Anatomic Stage IIIA Breast Cancer AJCC v8, Anatomic Stage IIIB Breast Cancer AJCC v8, Anatomic Stage IIIC Breast Cancer AJCC v8, Cancer Fatigue, Cancer Survivor, Complete Remission, Prognostic Stage I Breast Cancer AJCC v8, Prognostic Stage IA Breast Cancer AJCC v8, Prognostic Stage IB Breast Cancer AJCC v8, Prognostic Stage II Breast Cancer AJCC v8, Prognostic Stage IIA Breast Cancer AJCC v8, Prognostic Stage IIB Breast Cancer AJCC v8, Prognostic Stage III Breast Cancer AJCC v8, Prognostic Stage IIIA Breast Cancer AJCC v8, Prognostic Stage IIIB Breast Cancer AJCC v8, Prognostic Stage IIIC Breast Cancer AJCC v8

Investigators

Heather S Jim, William J. Irvin, Shaker R. Dakhil, Bryan A. Faller, Ki Y. Chung, Elie G. Dib, Timothy D. Moore, Kathleen J. Yost, Vicki A. Morrison, Rakesh Gaur

See list of participating sites