Major Program
Supportive Care and Symptom Management
NCI Community Oncology Research Program
Research Group
Community Oncology and Prevention Trials
Sponsor
Alliance for Clinical Trials in Oncology
Status
Recruiting
ClinicalTrials.gov ID
For more information, see ClinicalTrials.gov NCT04379570
This phase III trial compares an additional support program (text message reminders and/or
telephone-based counseling) with usual care in making sure breast cancer patients take their
endocrine therapy medication as prescribed (medication adherence). Medication adherence is
how well patients take the medication as prescribed by their doctors, and good medical
adherence is when patients take medications correctly. Poor medication adherence has been
shown to be a serious barrier to effective treatment for hormone receptor positive breast
cancer patients. Adding text message reminders and/or telephone-based counseling to usual
care may increase the number of days that patients take their endocrine therapy medication as
prescribed.
telephone-based counseling) with usual care in making sure breast cancer patients take their
endocrine therapy medication as prescribed (medication adherence). Medication adherence is
how well patients take the medication as prescribed by their doctors, and good medical
adherence is when patients take medications correctly. Poor medication adherence has been
shown to be a serious barrier to effective treatment for hormone receptor positive breast
cancer patients. Adding text message reminders and/or telephone-based counseling to usual
care may increase the number of days that patients take their endocrine therapy medication as
prescribed.
Intervention
Educational Intervention, Text Message-based Navigation Intervention, Motivational Interviewing, Best Practice, Questionnaire Administration, Quality-of-Life Assessment
Condition
Anatomic Stage I Breast Cancer AJCC v8, Anatomic Stage II Breast Cancer AJCC v8, Anatomic Stage III Breast Cancer AJCC v8, HER2 Negative Breast Carcinoma, Hormone Receptor Positive Breast Carcinoma, Invasive Breast Carcinoma, Prognostic Stage I Breast Cancer AJCC v8, Prognostic Stage II Breast Cancer AJCC v8, Prognostic Stage III Breast Cancer AJCC v8
Investigators
Katherine E. Reeder-Hayes, MD, Debra M. Prow, Jeffrey J. Kirshner, Jay W. Carlson, Bryan A. Faller, David M. Spector, Shaker R. Dakhil, Corrine L. Zarwan, Bachir J. Sakr, Asheesh Shipstone, V. S. Klimberg, Daniel M. Anderson, Amanda R. Hathaway, Mehmet F. Hepgur, Karen B. Russell, William E. Burak, Pratima Chalasani, Isoken Koko, Ashkan Bahrani, Karthik V. Giridhar, Preston D. Steen, David B. Sokol, Katherine E. Reeder-Hayes, Samer S. Kasbari, Ernest Hymel, William J. Irvin, Timothy R. Wassenaar, Gabrielle B. Rocque, Nicholas DiBella, Richard L. Deming, Richard C. Frank, Shylendra B. Sreenivasappa, Flavio W. Kruter, Yadyra Rivera, Ethan Binder, Bolanle Gbadamosi, Bradley T. Clifford, Sunitha Vemulapalli, Alison K. Conlin, Jeffrey A. Stevens, Alastair M. Thompson, Gary W. Unzeitig, Harish G. Ahuja, Banu E. Symington, Howard M. Gross, William P. Fusselman, Deborah W. Wilbur, Brenda K. Davis, Cynthia M. Vakhariya, Puja Nistala, John A. Ellerton, Priya P. Gor, Timothy D. Moore, Jennifer Slim, Ranveer Nand, Demet Gokalp Yasar, Judy M. Cheng, Joshua Lukenbill, Young J. Lee, Radhika Rachamalla, Ellis G. Levine, Mark L. Graham, John M. Cho, Albert S. DeNittis, Pallav Mehta, Ki Y. Chung, Thomas J. Summers, Anthony J. Jaslowski, Lara N. Durna, Thomas J. Saphner, Ivy Abraham, Daulath Singh, Kathleen J. Yost, Bret E. Friday, John M. Schallenkamp, Mahvish Muzaffar, Jennifer E. Vaughn, Natalya Greyz-Yusupov, Cherif N. Boutros, William M. Sikov, Jay B. Nayak, Robert M. Kyler, Christa Braun-Inglis, Rachel A. Freedman, Mylene S. Go, Toby C. Campbell, Jennifer L. Heaberlin, Richard J. Bold, Janie G. Weng Grumley, Gary V. Burton, Pooja Murthy, Praveen Vashist, Sailaja Kamaraju, Uma Suryadevara, Gregory A. Masters, Sharad A. Ghamande, David A. Riseberg, Tareq Al Baghdadi, Maria D. Thomson, Nicole L. Whitlatch, Alexander Menter, Selvi Lingam, John Pellegrino, Gopal R. Desai, Mary Anne Fenton