Supportive Care and Symptom Management

The Supportive Care and Symptom Management program supports studies on the prevention or treatment of acute and chronic symptoms and morbidities related to cancer and its treatment. This includes the impact on the quality of life of patients and their informal caregivers. The program also supports studies of patients and their caregivers at the end of life.

About Supportive Care and Symptom Management

The program supports research in three areas: prevention or treatment of acute or chronic symptoms and morbidities related to cancer, its treatment and caregiving (symptom management research); effects on quality of life from cancer, its treatment and caregiving (quality of life research); and end-of-life psychosocial issues, caregiving and treatment strategies (end-of-life research).

Through the NCI Community Oncology Research Program (NCORP), clinical trials are underway to evaluate therapies to prevent or ameliorate a broad range of symptoms and/or toxicities associated with cancer its treatment and caregiving. Other studies funded separately are investigating a range of treatment effects on health-related quality of life and a variety of influences on the end-of-life cancer experience.

Topic Areas include: Anorexia, Cachexia, Cardiotoxicity, Caregiver Issues, Cognitive Dysfunction, Distress/Anxiety/Depression, End of Life, Fatigue, Geriatrics, Hot Flashes, Lymphedema, Medication Adherence, Mucositis, Multiple Symptoms, Musculoskeletal Symptoms, Nausea, Neuropathy, Nutrition, Oral Complications, Other Supportive Care Issues, Pain, Palliative Care, Pediatrics/Adolescents/Young Adult, Physical Functioning, Quality of Life, Skin Toxicities, Sleep Disorders, and Urinary Complications.

Selected Topics

Funding Opportunities

No matching Funding Opportunities were found.

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Grantee Details

PI Name Sort descending	PI Organization	Title	Grant Number	Program Official
Boutros, Paul Christopher	University Of California Los Angeles United States	Germline Determinants of Prostate Cancer Evolution	5R01CA270108-03	Guillermo Marquez, Ph.D.
Bower, Julienne E	University Of California Los Angeles United States	Mindfulness Meditation for Younger Breast Cancer Survivors: Testing Digital Interventions in Clinical and Community Settings	5R01CA282416-02	Brennan Streck, Ph.D., RN, M.P.H.
Bower, Julienne E	University Of California Los Angeles United States	Mindfulness Meditation for Younger Breast Cancer Survivors: Testing Digital Interventions in Clinical and Community Settings	5R01CA282416-02	Brennan Streck, Ph.D., RN, M.P.H.
Boyer, Thomas G	University Of Texas Hlth Science Center United States	Pathological reprogramming of the m6A epitranscriptome in uterine fibroids	5R01HD106285-05	Goli Samimi, Ph.D., M.P.H.
Brand, Randall	University Of Pittsburgh At Pittsburgh United States	Validation of biomarkers for risk prediction and early diagnosis of Pancreatic Adenocarcinoma	5U01CA200466-08	Matthew Young, Ph.D.
Brand, Randall	University Of Pittsburgh At Pittsburgh United States	Validation of biomarkers for risk prediction and early diagnosis of Pancreatic Adenocarcinoma	5U01CA200466-08	Matthew Young, Ph.D.
Brinkman, Tara M	St. Jude Children'S Research Hospital United States	Culturally adapted mobile treatment of chronic pain in adolescent survivors of pediatric bone sarcoma	4R33CA280978-02	Rachel Altshuler, Ph.D.
Brinkman, Tara M	St. Jude Children'S Research Hospital United States	Culturally adapted mobile treatment of chronic pain in adolescent survivors of pediatric bone sarcoma	4R33CA280978-02	Rachel Altshuler, Ph.D.
Brown, Austin L	Baylor College Of Medicine United States	A Systems Epidemiology Approach for Predicting Methotrexate Neurotoxicity in Pediatric Acute Leukemia	5R01CA272981-03	Rachel Altshuler, Ph.D.
Brown, Austin L	Baylor College Of Medicine United States	A Systems Epidemiology Approach for Predicting Methotrexate Neurotoxicity in Pediatric Acute Leukemia	5R01CA272981-03	Rachel Altshuler, Ph.D.
Brown, Austin L	Baylor College Of Medicine United States	A Systems Epidemiology Approach for Predicting Methotrexate Neurotoxicity in Pediatric Acute Leukemia	5R01CA272981-03	Rachel Altshuler, Ph.D.
Bruner, Deborah Watkins	Nrg Oncology Foundation, Inc. United States	NRG Oncology NCORP Research Base-BIQSFP	3UG1CA189867-11S2	Brandy Heckman-Stoddard, Ph.D., M.P.H.
Bruner, Deborah Watkins	Nrg Oncology Foundation, Inc. United States	NRG Oncology NCORP Research Base-BIQSFP	3UG1CA189867-11S2	Brandy Heckman-Stoddard, Ph.D., M.P.H.
Bryan, Angela	University Of Colorado United States	Cannabis for Palliative Care in Cancer: A Placebo-controlled Randomized Trial of Full Spectrum Hemp-derived CBD/THC	5R01CA284860-03	Brennan Streck, Ph.D., RN, M.P.H.
Bryan, Angela	University Of Colorado United States	Cannabis for Palliative Care in Cancer: A Placebo-controlled Randomized Trial of Full Spectrum Hemp-derived CBD/THC	5R01CA284860-03	Brennan Streck, Ph.D., RN, M.P.H.

Clinical Trials

Title Sort descending	Intervention	Sponsor	Status
Fisetin to Improve Physical Function in Stage I-III Breast Cancer Survivors	Biospecimen Collection, Fisetin, Placebo Administration, Quality-of-Life Assessment, Questionnaire Administration	Jonsson Comprehensive Cancer Center	Recruiting
Flibanserin in Men Receiving Androgen Suppression for Prostate Cancer	Androgen deprivation therapy, Flibanserin 100 MG, Placebo	Andrew McDonald	Active, not recruiting
Genetic Analysis in Identifying Late-Occurring Complications in Childhood Cancer Survivors	Laboratory Biomarker Analysis, Questionnaire Administration	Children's Oncology Group	Active, not recruiting
Geriatric Evaluation and Management With Survivorship Health Education for Older Survivors of Cancer, GEM-S Trial	Best Practice, Comprehensive Geriatric Assessment, Educational Intervention, Exercise Intervention, Questionnaire Administration, Tailored Intervention	University of Rochester	Recruiting
Gut Microbe Composition, Exercise, and Breast Breast Cancer Survivors	Aerobic Exercise Training, Attention Control	University of Alabama at Birmingham	Active, not recruiting
Haloperidol and Lorazepam in Controlling Symptoms of Persistent Agitated Delirium in Patients With Advanced Cancer Undergoing Palliative Care	Haloperidol, Lorazepam, Placebo, Quality-of-Life Assessment, Questionnaire Administration	M.D. Anderson Cancer Center	Active, not recruiting
High-Dose Vitamin D Supplementation for ADT-Induced Bone Loss in Older Prostate Cancer Patients	Biospecimen Collection, D Vitamin, Dual X-ray Absorptiometry, Placebo Administration, Quality-of-Life Assessment, Questionnaire Administration	University of Rochester NCORP Research Base	Recruiting
Immune Checkpoint Inhibitor Toxicity Risk Prediction in Solid Tumors	Biospecimen Collection, Questionnaire Administration	SWOG Cancer Research Network	Recruiting
Impact of Sentinel Lymph Node Mapping on Patient Reported Lower Extremity Limb Dysfunction in Stage I Endometrial Cancer	Biospecimen Collection, Diagnostic Imaging Testing, Excisional Biopsy, Indocyanine Green Solution, Minimally Invasive Surgery, Pelvic Lymphadenectomy, Questionnaire Administration, Sentinel Lymph Node Mapping	NRG Oncology	Recruiting
Improving Adolescent and Young Adult Self-Reported Data in ECOG-ACRIN Trials	Questionnaires	Eastern Cooperative Oncology Group	Recruiting