Lactobacillus Plantarum in Preventing Acute Graft Versus Host Disease in Children Undergoing Donor Stem Cell Transplant

Major Program(s) or Research Group(s)

  • Community Oncology and Prevention Trials
  • NCI Community Oncology Research Program
  • Supportive Care and Symptom Management

Sponsor

Children's Oncology Group

Status

Active, not recruiting

ClinicalTrials.gov ID

For more information, see ClinicalTrials.gov NCT03057054

This randomized phase III trial studies how well Lactobacillus plantarum works in preventing
acute graft versus host disease in children undergoing donor stem cell transplant.
Lactobacillus plantarum may help prevent the development of gastrointestinal graft versus
host disease in children, adolescents, and young adults undergoing donor stem cell
transplant.

Intervention

Allogeneic Hematopoietic Stem Cell Transplantation, Lactobacillus plantarum strain 299, Lactobacillus plantarum strain 299v, Placebo Administration

Condition

Hematopoietic and Lymphoid System Neoplasm, Leukemia, Lymphoma, Plasma Cell Myeloma

Investigators

Michael L Nieder

See list of participating sites