The Supportive Care and Symptom Management program supports studies on the prevention or treatment of acute and chronic symptoms and morbidities related to cancer and its treatment. This includes the impact on the quality of life of patients and their informal caregivers. The program also supports studies of patients and their caregivers at the end of life.
On This Page
- All Heading 2s will automatically be pulled in to this list.
- Do not edit the content on this template.
About Supportive Care and Symptom Management
The program supports research in three areas: prevention or treatment of acute or chronic symptoms and morbidities related to cancer, its treatment and caregiving (symptom management research); effects on quality of life from cancer, its treatment and caregiving (quality of life research); and end-of-life psychosocial issues, caregiving and treatment strategies (end-of-life research).
Through the NCI Community Oncology Research Program (NCORP), clinical trials are underway to evaluate therapies to prevent or ameliorate a broad range of symptoms and/or toxicities associated with cancer its treatment and caregiving. Other studies funded separately are investigating a range of treatment effects on health-related quality of life and a variety of influences on the end-of-life cancer experience.
Topic Areas include: Anorexia, Cachexia, Cardiotoxicity, Caregiver Issues, Cognitive Dysfunction, Distress/Anxiety/Depression, End of Life, Fatigue, Geriatrics, Hot Flashes, Lymphedema, Medication Adherence, Mucositis, Multiple Symptoms, Musculoskeletal Symptoms, Nausea, Neuropathy, Nutrition, Oral Complications, Other Supportive Care Issues, Pain, Palliative Care, Pediatrics/Adolescents/Young Adult, Physical Functioning, Quality of Life, Skin Toxicities, Sleep Disorders, and Urinary Complications.
Selected Topics
- HEAL Initiative
- Patient Resources on Side Effects of Cancer Treatment
- Patient Resources on Coping with Cancer
Resources
-
Building Bridges in Cancer Symptom Science Webinar SeriesThis series is aimed at bringing together interdisciplinary researchers in cancer symptom science to share their expertise and further discussions in the field.
-
DCP Early Career Scientist Spotlight Research Seminar SeriesThis seminar series highlights nominated early career scientists who are advancing research within the areas supported by DCP.
Funding Opportunities
No matching Funding Opportunities were found.
Grantee Details
Clinical Trials
| Title | Intervention | Sponsor Sort descending | Status |
|---|---|---|---|
| Testing Laser Therapy for Treatment of Vaginal Dryness in Survivors of Breast Cancer, The Revitalize Trial | Laser Therapy, Quality of Life Assessment, Questionnaire Administration, Sham Intervention | Alliance for Clinical Trials in Oncology | Not yet recruiting |
| Distance-Based Exercise to Preserve Function and Prevent Disability | Accelerometry, Aerobic Exercise Intervention, Dumbbell Exercise Intervention, Electronic Health Record Review, Exercise intervention, Interview, Questionnaire Administration, Telemedicine | Alliance for Clinical Trials in Oncology | Not yet recruiting |
| Flibanserin in Men Receiving Androgen Suppression for Prostate Cancer | Androgen deprivation therapy, Flibanserin 100 MG, Placebo | Andrew McDonald | Active, not recruiting |
| Computer Training Program for Younger Patients With a Brain Tumor Who Underwent Radiation Therapy | Cognitive Assessment, Computer-Assisted Cognitive Training, Psychosocial Assessment and Care, Quality-of-Life Assessment, Questionnaire Administration | Children's Oncology Group | Active, not recruiting |
| A Study to See if Memantine Protects the Brain During Radiation Therapy Treatment for a Brain Tumor | Biospecimen Collection, Cognitive Assessment, Magnetic Resonance Imaging, Memantine Hydrochloride, Placebo Administration, Questionnaire Administration | Children's Oncology Group | Active, not recruiting |
| Mobile Health and Social Media Physical Activity Intervention Among Adolescent and Young Adult Childhood Cancer Survivors, the StepByStep Study | Educational Intervention, FitBit, Goal Setting, Health Promotion and Education, Media Intervention, Telephone-Based Intervention | Children's Oncology Group | Active, not recruiting |
| Late Effects After Treatment in Patients With Previously Diagnosed High-Risk Neuroblastoma | Cytology Specimen Collection Procedure, Laboratory Biomarker Analysis, Quality-of-Life Assessment | Children's Oncology Group | Active, not recruiting |
| Assessing Compliance With Mercaptopurine Treatment in Younger Patients With Acute Lymphoblastic Leukemia in First Remission | Behavioral Intervention, Compliance Monitoring, Laboratory Biomarker Analysis, Mercaptopurine, Questionnaire Administration, Standard Follow-Up Care | Children's Oncology Group | Active, not recruiting |
| Lactobacillus Plantarum in Preventing Acute Graft Versus Host Disease in Children Undergoing Donor Stem Cell Transplant | Allogeneic Hematopoietic Stem Cell Transplantation, Lactobacillus plantarum strain 299, Lactobacillus plantarum strain 299v, Placebo Administration | Children's Oncology Group | Active, not recruiting |
| Web-Based Physical Activity Intervention in Improving Long Term Health in Children and Adolescents With Cancer | Educational Intervention, Internet-Based Intervention, Laboratory Biomarker Analysis, Medical Device Usage and Evaluation, Quality-of-Life Assessment, Questionnaire Administration | Children's Oncology Group | Active, not recruiting |
News and Events
Early Career Scientist Seminar - Drs. Khurana and Harris
Date Posted: January 2, 2026
Early Career Scientist Seminar - Drs. Knoerl and Meisel
Date Posted: January 2, 2026
Early Career Scientist Seminar - Drs. Raufi and Skiba
Date Posted: January 2, 2026
Early Career Scientist Seminar - Drs. Shay and Yates
Date Posted: January 2, 2026
Early Career Scientist Seminar - Drs. Wang and Martel
Date Posted: January 2, 2026