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Supportive Care and Symptom Management

The Supportive Care and Symptom Management program supports studies on the prevention or treatment of acute and chronic symptoms and morbidities related to cancer and its treatment. This includes the impact on the quality of life of patients and their informal caregivers. The program also supports studies of patients and their caregivers at the end of life.

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About Supportive Care and Symptom Management

The program supports research in three areas: prevention or treatment of acute or chronic symptoms and morbidities related to cancer, its treatment and caregiving (symptom management research); effects on quality of life from cancer, its treatment and caregiving (quality of life research); and end-of-life psychosocial issues, caregiving and treatment strategies (end-of-life research).

Through the NCI Community Oncology Research Program (NCORP), clinical trials are underway to evaluate therapies to prevent or ameliorate a broad range of symptoms and/or toxicities associated with cancer its treatment and caregiving. Other studies funded separately are investigating a range of treatment effects on health-related quality of life and a variety of influences on the end-of-life cancer experience. 

Topic Areas include: Anorexia, Cachexia, Cardiotoxicity, Caregiver Issues, Cognitive Dysfunction, Distress/Anxiety/Depression, End of Life, Fatigue, Geriatrics, Hot Flashes, Lymphedema, Medication Adherence, Mucositis, Multiple Symptoms, Musculoskeletal Symptoms, Nausea, Neuropathy, Nutrition, Oral Complications, Other Supportive Care Issues, Pain, Palliative Care, Pediatrics/Adolescents/Young Adult, Physical Functioning, Quality of Life, Skin Toxicities, Sleep Disorders, and Urinary Complications.

Selected Topics

Resources

Funding Opportunities

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Grantee Details

PI Name PI Organization Title Grant Number Program Official
Rini, Christine

Northwestern University At Chicago
United States

Web-based Pain Coping Skills Training to Improve Pain and Poor Adherence caused by Aromatase Inhibitor-Associated Arthralgia In Breast Cancer Survivors (SKIP-Arthralgia): A Randomized Controlled Trial 5R01CA271220-04 Brennan Streck, Ph.D., RN, M.P.H.
Zheng, Qin

Johns Hopkins University
United States

Determining the function of medium to large diameter sensory neurons in paclitaxel-induced pain via large-scale in vivo DRG imaging 1R01CA291906-01A1 Rachel Altshuler, Ph.D.
Eldridge, Ronald C

Emory University
United States

Integrative Multi-Omics of Metabolomics and Epigenetics to Explore thePathophysiology of Cachexia and Survival in Head and Neck SquamousCell Carcinoma 1R03CA304028-01 Marjorie Perloff, M.D.
Vijayvergia, Namrata

Research Inst Of Fox Chase Can Ctr
United States

Exploring the Neuroprotective Potential of CBD in Preventing Oxaliplatin-Induced Neuropathy: A Prospective Study 1R21CA292276-01A1 Rachel Altshuler, Ph.D.
Gill, Brian John Andrew

Columbia University Health Sciences
United States

The Impact of Local and Reversible Change to GABAergic Inhibitory Signaling on Tumor-Induced Cortical Dysfunction in Glioma 1R01NS140658-01A1 Brandy Heckman-Stoddard, Ph.D., M.P.H.
Prigerson, Holly Gwen

Weill Medical Coll Of Cornell Univ
United States

Behavioral and Psychosocial Effects on Study Outcomes in End-Stage Cancer Treatment (BEST End-Stage Cancer Study) 5R35CA197730-11 Brennan Streck, Ph.D., RN, M.P.H.
Hu, Jim

Weill Medical Coll Of Cornell Univ
United States

Pelvic fascia spARing radical prostatectomy TrIAL (PARTIAL) 5R01CA259173-04 Marjorie Perloff, M.D.
Morin, Olivier

University Of California, San Francisco
United States

Development of a Personalized Voxel-wise Prediction of Brain Metastases using Multi-Parametric MR Imaging to Reduce Treatment Toxicity 1R01CA292043-01A1 Marjorie Perloff, M.D.
Upshaw, Jenica

Beth Israel Deaconess Medical Center
United States

A randomized trial of cardioprotective strategies in newly diagnosed diffuse large B-cell lymphoma and pre-existing cardiomyopathy or prior anthracycline exposure 1R37CA300969-01 Eileen Dimond, R.N., M.S.
Delaney, Joe R

Medical University Of South Carolina
United States

Biologic rationale of fallopian tube removal to prevent uterine serous carcinoma 1R21CA292343-01A1 Goli Samimi, Ph.D., M.P.H.
Judge, Andrew Robert

University Of Florida
United States

The Complement System and Cancer Cachexia 5R01AR081648-04 Brandy Heckman-Stoddard, Ph.D., M.P.H.
Perez-Lougee, Giselle Katiria

Massachusetts General Hospital
United States

Thriving Beyond Treatment: A Resilience-Based Approach to Improve Long-term Quality of Life in Post-treatment Lymphoma Survivorship 1R37CA303094-01 Marjorie Perloff, M.D.
Im, Eun-Ok

University Of Texas At Austin
United States

Cancer Pain Management: A Technology-Based Intervention for Asian American Breast Cancer Survivors 5R33CA280979-04 Brennan Streck, Ph.D., RN, M.P.H.
Garcia, Jose M.

Seattle Inst For Biomedical/Clinical Res
United States

SArcopenia in Men with Prostate Cancer undergoing ADT (SAP-ADT) 5R01CA279220-03 Marjorie Perloff, M.D.

Clinical Trials

Status
Title Sort ascending Intervention Sponsor Status
Cognitive Training for Cancer Related Cognitive Impairment in Breast Cancer Survivors Arm 1: Computerized Cognitive Training-Global Stimulation Games, Arm 2: Computerized Cognitive Training-Neuroplasticity Games NRG Oncology Recruiting
Cancer and Blood Pressure Management, CARISMA Study Best Practice, Blood Pressure Measurement, Clinical Management, Quality-of-Life Assessment, Questionnaire Administration ECOG-ACRIN Cancer Research Group Active, not recruiting
Bupropion to Reduce Cancer Related Fatigue in Cancer Survivors Biospecimen Collection, Bupropion Hydrochloride Controlled-release, Placebo Administration, Quality-of-Life Assessment, Questionnaire Administration University of Rochester NCORP Research Base Active, not recruiting
Axillary Reverse Mapping in Preventing Lymphedema in Patients With Breast Cancer Undergoing Axillary Lymph Node Dissection Axillary Lymph Node Dissection, Isosulfan Blue, Mapping, Quality-of-Life Assessment, Questionnaire Administration Alliance for Clinical Trials in Oncology Active, not recruiting
Assessment of Cognitive Function in Breast Cancer and Lymphoma Patients Receiving Chemotherapy University of Rochester NCORP Research Base Enrolling by invitation
Assessing Compliance With Mercaptopurine Treatment in Younger Patients With Acute Lymphoblastic Leukemia in First Remission Behavioral Intervention, Compliance Monitoring, Laboratory Biomarker Analysis, Mercaptopurine, Questionnaire Administration, Standard Follow-Up Care Children's Oncology Group Active, not recruiting
Assessing Benefits and Harms of Cannabis/Cannabinoid Use Among Cancer Patients Treated in Community Oncology Clinics Non-interventional Study Wake Forest University Health Sciences Recruiting
An Internet-based Program to Help Cancer Survivors Manage Pain Internet-based pain coping skills program Wake Forest University Health Sciences Recruiting
Additional Support Program Via Text Messaging and Telephone-Based Counseling for Breast Cancer Patients Receiving Hormonal Therapy Best Practice, Educational Intervention, Motivational Interviewing, Quality-of-Life Assessment, Questionnaire Administration, Text Message-based Navigation Intervention Alliance for Clinical Trials in Oncology Active, not recruiting
A Web-based Program to Help Caregivers of Lung Patients Learn About Available Supportive Care Resources Internet-Based Intervention - CONNECT, Patient Navigation, Support for Caregiver - Generic List, Support for Caregiver - Personalized List Wake Forest University Health Sciences Active, not recruiting