Skip to main content
An official website of the United States government

Supportive Care and Symptom Management

The Supportive Care and Symptom Management program supports studies on the prevention or treatment of acute and chronic symptoms and morbidities related to cancer and its treatment. This includes the impact on the quality of life of patients and their informal caregivers. The program also supports studies of patients and their caregivers at the end of life.

On This Page

  • All Heading 2s will automatically be pulled in to this list.
  • Do not edit the content on this template.

About Supportive Care and Symptom Management

The program supports research in three areas: prevention or treatment of acute or chronic symptoms and morbidities related to cancer, its treatment and caregiving (symptom management research); effects on quality of life from cancer, its treatment and caregiving (quality of life research); and end-of-life psychosocial issues, caregiving and treatment strategies (end-of-life research).

Through the NCI Community Oncology Research Program (NCORP), clinical trials are underway to evaluate therapies to prevent or ameliorate a broad range of symptoms and/or toxicities associated with cancer its treatment and caregiving. Other studies funded separately are investigating a range of treatment effects on health-related quality of life and a variety of influences on the end-of-life cancer experience. 

Topic Areas include: Anorexia, Cachexia, Cardiotoxicity, Caregiver Issues, Cognitive Dysfunction, Distress/Anxiety/Depression, End of Life, Fatigue, Geriatrics, Hot Flashes, Lymphedema, Medication Adherence, Mucositis, Multiple Symptoms, Musculoskeletal Symptoms, Nausea, Neuropathy, Nutrition, Oral Complications, Other Supportive Care Issues, Pain, Palliative Care, Pediatrics/Adolescents/Young Adult, Physical Functioning, Quality of Life, Skin Toxicities, Sleep Disorders, and Urinary Complications.

Selected Topics

Funding Opportunities

No matching Funding Opportunities were found.

View All Funding Opportunities

Grantee Details

PI Name Sort descending PI Organization Title Grant Number Program Official
Chan, Daniel Wanyui

Johns Hopkins University
United States

Development of a panel of multiplex biomarkers for the early detection of pancreatic ductal adenocarcinoma and high-risk lesions 5U01CA274514-03 Matthew Young, Ph.D.
Chan, Andrew T

Massachusetts General Hospital
United States

Precision Prevention Research Program 5R35CA253185-06 Asad Umar, D.V.M., Ph.D.
Chan, Daniel Wanyui

Johns Hopkins University
United States

BCC for Prostate Cancer: Discovery and Translation of Biomarkers for Clinical Unmet Needs 5U2CCA271895-03 Indu Kohaar, Ph.D., M.Phil., M.Sc.
Chapkin, Robert Stephen

Texas A&M Agrilife Research
United States

Targeting plasma membrane spatial dynamics to suppress aberrant Wnt signaling 5R01CA244359-05 Amit Kumar, Ph.D.
Chen, Ru

Baylor College Of Medicine
United States

BLOOD-BASED PROTEOMIC ASSAY FOR PANCREATIC CANCER DETECTION 4UH3CA292130-02 Claire Zhu, Ph.D.
Chen, Grace Y.

University Of Michigan At Ann Arbor
United States

Targeting cancer stem-like cells and inflammation for colon cancer chemoprevention 5R21CA273646-02
Cheville, Andrea Lynne

Mayo Clinic Rochester
United States

Achieving Safe, Comprehensive, Digitally-Enabled Cancer Pain managemeNT” (ASCENT) Clinical Trial 5R33CA278594-04 Brennan Streck, Ph.D., RN, M.P.H.
Cheville, Andrea Lynne

Mayo Clinic Rochester
United States

Achieving Safe, Comprehensive, Digitally-Enabled Cancer Pain managemeNT” (ASCENT) Clinical Trial 5R33CA278594-04 Brennan Streck, Ph.D., RN, M.P.H.
Chiang, Cheng-Ming

Ut Southwestern Medical Center
United States

Small Compound Inhibitors Targeting HPV Genome Replication 1R01CA288743-01A1
Chibwesha, Carla J

Univ Of North Carolina Chapel Hill
United States

Acceptability and feasibility of combination treatment for cervical precancer among South Africa women living with HIV 5R01CA250850-05 Vikrant Sahasrabuddhe, M.B.B.S., M.P.H., Dr.P.H.
Chinnaiyan, Arul M

University Of Michigan At Ann Arbor
United States

Michigan-VUMC Biomarker Characterization Center 5U2CCA271854-04 Indu Kohaar, Ph.D., M.Phil., M.Sc.
Chirenje, Zvavahera Mike

University Of California, San Francisco
United States

Implementing HIV/Cervical Cancer Prevention CASCADE Clinical Trials in Zimbabwe (ZIM-CASCADE) 3UG1CA284918-03S1 Maria Silvina Frech, Ph.D., M.S.
Chong, Catherine Daniela

Mayo Clinic Arizona
United States

Biomarker Signature to Predict the Persistence of Post-Traumatic Headache 5R33NS113315-03 Brandy Heckman-Stoddard, Ph.D., M.P.H.
Chong, Catherine Daniela

Mayo Clinic Arizona
United States

Biomarker Signature to Predict the Persistence of Post-Traumatic Headache 5R33NS113315-03 Brandy Heckman-Stoddard, Ph.D., M.P.H.
Chung, Raymond T

Massachusetts General Hospital
United States

Trial of Statins for Chemoprevention in Hepatocellular Carcinoma 4R01CA255621-05 Asad Umar, D.V.M., Ph.D.

Clinical Trials

Status
Title Sort descending Intervention Sponsor Status
Olanzapine Versus Megestrol Acetate for the Treatment of Loss of Appetite Among Advanced Cancer Patients Megestrol Acetate, Olanzapine, Questionnaire Administration Alliance for Clinical Trials in Oncology Recruiting
Palbociclib and Letrozole or Fulvestrant in Treating Patients With Estrogen Receptor Positive, HER2 Negative Metastatic Breast Cancer Fulvestrant, Letrozole, Palbociclib, Quality-of-Life Assessment, Questionnaire Administration Alliance for Clinical Trials in Oncology Active, not recruiting
Pathways, a Hope Intervention to Support Personal Goal Pursuit, Mental Health, and Quality of Life During Advanced Lung Cancer Treatment Enhanced Usual Care, Pathways Laurie McLouth Recruiting
Pregnancy Outcome and Safety of Interrupting Therapy for Women With Endocrine Responsive Breast Cancer Endocrine therapy interruption ETOP IBCSG Partners Foundation Active, not recruiting
Prevention of Frailty With Fisetin and Exercise in Breast Cancer Survivors Biospecimen Collection, Educational Intervention, Exercise Intervention, Fisetin, Physical Performance Testing, Placebo Administration, Quality-of-Life Assessment, Questionnaire Administration Jonsson Comprehensive Cancer Center Recruiting
Prophylactic Antiviral Therapy in Patients With Current or Past Hepatitis B Virus Infection Receiving Anti-Cancer Therapy for Solid Tumors Entecavir, Tenofovir Disoproxil Fumarate, Best Practice, Tenofovir Alafenamide SWOG Cancer Research Network Active, not recruiting
Reaching Rural Cancer Survivors Who Smoke Using Text-Based Program Health Promotion and Education, Informational Intervention, Questionnaire Administration, Smoking Cessation Intervention Alliance for Clinical Trials in Oncology Recruiting
Relaxation for Women With Breast Cancer Undergoing Radiotherapy Questionnaires, Relaxation Program, Saliva Testing M.D. Anderson Cancer Center Active, not recruiting
Reproductive Health Program in Patients With Cancer Standard practice related to reproductive heath, Training modules, algorithm, referral development ECOG-ACRIN Cancer Research Group Active, not recruiting
REVITALIZE: RCT to Reduce Fatigue in Adults With Ovarian Cancer on PARP Inhibitors Educational Materials, REVITALIZE Intervention Dana-Farber Cancer Institute Recruiting