Major Program
Supportive Care and Symptom Management
NCI Community Oncology Research Program
Research Group
Community Oncology and Prevention Trials
Sponsor
ECOG-ACRIN Cancer Research Group
Status
Active, not recruiting
ClinicalTrials.gov ID
For more information, see ClinicalTrials.gov NCT04001829
This phase II trial studies how well docetaxel or paclitaxel work in reducing
chemotherapy-induced peripheral neuropathy in African American patients with stages I-III
breast cancer. Drugs used in chemotherapy, such as docetaxel and paclitaxel, work in
different ways to stop the growth of tumor cells, either by killing the cells, by stopping
them from dividing, or by stopping them from spreading. It is not yet known whether giving
docetaxel or paclitaxel may work better than other methods in reducing chemotherapy-induced
peripheral neuropathy in patients with breast cancer.
chemotherapy-induced peripheral neuropathy in African American patients with stages I-III
breast cancer. Drugs used in chemotherapy, such as docetaxel and paclitaxel, work in
different ways to stop the growth of tumor cells, either by killing the cells, by stopping
them from dividing, or by stopping them from spreading. It is not yet known whether giving
docetaxel or paclitaxel may work better than other methods in reducing chemotherapy-induced
peripheral neuropathy in patients with breast cancer.
Intervention
Docetaxel, Paclitaxel, Quality-of-Life Assessment, Questionnaire Administration
Condition
Anatomic Stage I Breast Cancer AJCC v8, Anatomic Stage IA Breast Cancer AJCC v8, Anatomic Stage IB Breast Cancer AJCC v8, Anatomic Stage II Breast Cancer AJCC v8, Anatomic Stage IIA Breast Cancer AJCC v8, Anatomic Stage IIB Breast Cancer AJCC v8, Anatomic Stage III Breast Cancer AJCC v8, Anatomic Stage IIIA Breast Cancer AJCC v8, Anatomic Stage IIIB Breast Cancer AJCC v8, Anatomic Stage IIIC Breast Cancer AJCC v8, Invasive Breast Carcinoma, Prognostic Stage I Breast Cancer AJCC v8, Prognostic Stage IA Breast Cancer AJCC v8, Prognostic Stage IB Breast Cancer AJCC v8, Prognostic Stage II Breast Cancer AJCC v8, Prognostic Stage IIA Breast Cancer AJCC v8, Prognostic Stage IIB Breast Cancer AJCC v8, Prognostic Stage III Breast Cancer AJCC v8, Prognostic Stage IIIA Breast Cancer AJCC v8, Prognostic Stage IIIB Breast Cancer AJCC v8, Prognostic Stage IIIC Breast Cancer AJCC v8
Investigators
Bryan P Schneider