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Supportive Care and Symptom Management

The Supportive Care and Symptom Management program supports studies on the prevention or treatment of acute and chronic symptoms and morbidities related to cancer and its treatment. This includes the impact on the quality of life of patients and their informal caregivers. The program also supports studies of patients and their caregivers at the end of life.

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About Supportive Care and Symptom Management

The program supports research in three areas: prevention or treatment of acute or chronic symptoms and morbidities related to cancer, its treatment and caregiving (symptom management research); effects on quality of life from cancer, its treatment and caregiving (quality of life research); and end-of-life psychosocial issues, caregiving and treatment strategies (end-of-life research).

Through the NCI Community Oncology Research Program (NCORP), clinical trials are underway to evaluate therapies to prevent or ameliorate a broad range of symptoms and/or toxicities associated with cancer its treatment and caregiving. Other studies funded separately are investigating a range of treatment effects on health-related quality of life and a variety of influences on the end-of-life cancer experience. 

Topic Areas include: Anorexia, Cachexia, Cardiotoxicity, Caregiver Issues, Cognitive Dysfunction, Distress/Anxiety/Depression, End of Life, Fatigue, Geriatrics, Hot Flashes, Lymphedema, Medication Adherence, Mucositis, Multiple Symptoms, Musculoskeletal Symptoms, Nausea, Neuropathy, Nutrition, Oral Complications, Other Supportive Care Issues, Pain, Palliative Care, Pediatrics/Adolescents/Young Adult, Physical Functioning, Quality of Life, Skin Toxicities, Sleep Disorders, and Urinary Complications.

Selected Topics

Resources

Funding Opportunities

No matching Funding Opportunities were found.

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Grantee Details

PI Name Sort descending PI Organization Title Grant Number Program Official
Santomasso, Bianca Denise

Sloan-Kettering Inst Can Research
United States

Comprehensive Molecular and Clinical Characterization of Acute and Chronic Neurotoxicity Following CAR-T Cell Therapy 5R01CA293922-02 Monica Epstein, B.S.N., RN, OCN
Schaverien, Mark V

University Of Tx Md Anderson Can Ctr
United States

Lymphedema Prevention Through Immediate Lymphatic Reconstruction 5R01CA292908-02 Brandy Heckman-Stoddard, Ph.D., M.P.H.
Sedrak, Mina S

University Of California Los Angeles
United States

Targeting Senescence to Mitigate Chemotherapy-induced Functional Decline 5R01CA280088-03 Goli Samimi, Ph.D., M.P.H.
Shelby, Rebecca A

Duke University
United States

Improving outcomes for women experiencing premature or early menopause after cancer: development and pilot testing of a novel intervention 1R21CA301298-01 Goli Samimi, Ph.D., M.P.H.
Shelby, Rebecca A

Duke University
United States

Persistent Post-Mastectomy Pain: Randomized Clinical Trial of Targeted Pain Coping Skills Training (Targeted-PCST) with Mediational Analysis 5R01CA249959-05 Brennan Streck, Ph.D., RN, M.P.H.
Shiozawa, Yusuke

Wake Forest University Health Sciences
United States

Contribution of cutaneous neuro-immune interactions to chemotherapy-induced peripheral neuropathy 1R21CA297068-01 Rachel Altshuler, Ph.D.
Siskind, Leah J

University Of Louisville
United States

Protecting the kidney from cisplatin induced injury and progression to chronic kidney disease 1R01CA305985-01 Marjorie Perloff, M.D.
Sohl, Stephanie Jean

Wake Forest University Health Sciences
United States

REmotely-delivered Supportive Programs for Improving surgical pain and disTrEss (RESPITE) 5R01CA266995-04 Goli Samimi, Ph.D., M.P.H.
Spiegel, Brennan

Cedars-Sinai Medical Center
United States

Randomized Controlled Trial of Virtual Reality for GI Cancer Pain to Improve Patient Reported Outcomes 5R01CA252211-05 Rachel Altshuler, Ph.D.
Staff, Nathan P

Mayo Clinic Rochester
United States

Investigating the role of MAP2 in chemotherapy-induced peripheral neurotoxicity 5R01CA275870-03 Rachel Altshuler, Ph.D.
Storz, Peter

Mayo Clinic Jacksonville
United States

Deiminated molecules as markers for developing pancreatic cancer - A1 5R21CA279916-02 Matthew Young, Ph.D.
Taratula, Oleh

Oregon State University
United States

Novel Nanomedicine-Based Therapeutic Approach For Treatment of Cancer Cachexia 5R37CA234006-07 Brandy Heckman-Stoddard, Ph.D., M.P.H.
Upshaw, Jenica

Beth Israel Deaconess Medical Center
United States

A randomized trial of cardioprotective strategies in newly diagnosed diffuse large B-cell lymphoma and pre-existing cardiomyopathy or prior anthracycline exposure 1R37CA300969-01 Eileen Dimond, R.N., M.S.
Valdimarsdottir, Heiddis

Icahn School Of Medicine At Mount Sinai
United States

Systematic Light Exposure Effects on Circadian Rhythms Entrainment, Inflammation, Neutropenic Fever and Symptom Burden among Multiple Myeloma Patients undergoing Autologous Stem Cell Transplantation 5R01CA260961-04 Marjorie Perloff, M.D.
Veiseh, Omid

Rice University
United States

Bioengineered lymphatic regenerating platform for treatment of breast cancer related lymphedema 1R01HL179534-01 Goli Samimi, Ph.D., M.P.H.

Clinical Trials

Status
Title Sort descending Intervention Sponsor Status
Reaching Rural Cancer Survivors Who Smoke Using Text-Based Program Health Promotion and Education, Informational Intervention, Questionnaire Administration, Smoking Cessation Intervention Alliance for Clinical Trials in Oncology Recruiting
Relaxation for Women With Breast Cancer Undergoing Radiotherapy Questionnaires, Relaxation Program, Saliva Testing M.D. Anderson Cancer Center Active, not recruiting
Reproductive Health Program in Patients With Cancer Standard practice related to reproductive heath, Training modules, algorithm, referral development ECOG-ACRIN Cancer Research Group Active, not recruiting
REVITALIZE: RCT to Reduce Fatigue in Adults With Ovarian Cancer on PARP Inhibitors Educational Materials, REVITALIZE Intervention Dana-Farber Cancer Institute Recruiting
S1501 Dual Observational and Randomized Cohort Study of Patients With Metastatic HER-2+ Breast Cancer at Risk of Cardiac Toxicity Carvedilol, Laboratory Biomarker Analysis, Patient Observation SWOG Cancer Research Network Recruiting
Simplified Patient Care Strategy in Decreasing Early Death in Patients With Acute Promyelocytic Leukemia Laboratory Biomarker Analysis, Simplified Patient Care Strategy ECOG-ACRIN Cancer Research Group Active, not recruiting
Studying the Effect of Levocarnitine in Protecting the Liver From Chemotherapy for Leukemia or Lymphoma Biospecimen Collection, Calaspargase Pegol, Levocarnitine, Pegaspargase, Quality-of-Life Assessment Children's Oncology Group Recruiting
Studying the Physical Function and Quality of Life Before and After Surgery in Patients With Stage I Cervical Cancer Conization, Quality-of-Life Assessment, Questionnaire Administration, Therapeutic Conventional Surgery, Therapeutic Lymphadenectomy GOG Foundation Active, not recruiting
Surgical Thromboprophylaxis Practices in Oncology Patients Within the NCORP Network, STOP-VTE Study Non-Interventional Study Wake Forest University Health Sciences Recruiting
Taxane and Taxane-Induced Peripheral Neuropathy in African American Patients With Stage I-III Breast Cancer Docetaxel, Paclitaxel, Quality-of-Life Assessment, Questionnaire Administration ECOG-ACRIN Cancer Research Group Active, not recruiting