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Supportive Care and Symptom Management

The Supportive Care and Symptom Management program supports studies on the prevention or treatment of acute and chronic symptoms and morbidities related to cancer and its treatment. This includes the impact on the quality of life of patients and their informal caregivers. The program also supports studies of patients and their caregivers at the end of life.

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About Supportive Care and Symptom Management

The program supports research in three areas: prevention or treatment of acute or chronic symptoms and morbidities related to cancer, its treatment and caregiving (symptom management research); effects on quality of life from cancer, its treatment and caregiving (quality of life research); and end-of-life psychosocial issues, caregiving and treatment strategies (end-of-life research).

Through the NCI Community Oncology Research Program (NCORP), clinical trials are underway to evaluate therapies to prevent or ameliorate a broad range of symptoms and/or toxicities associated with cancer its treatment and caregiving. Other studies funded separately are investigating a range of treatment effects on health-related quality of life and a variety of influences on the end-of-life cancer experience. 

Topic Areas include: Anorexia, Cachexia, Cardiotoxicity, Caregiver Issues, Cognitive Dysfunction, Distress/Anxiety/Depression, End of Life, Fatigue, Geriatrics, Hot Flashes, Lymphedema, Medication Adherence, Mucositis, Multiple Symptoms, Musculoskeletal Symptoms, Nausea, Neuropathy, Nutrition, Oral Complications, Other Supportive Care Issues, Pain, Palliative Care, Pediatrics/Adolescents/Young Adult, Physical Functioning, Quality of Life, Skin Toxicities, Sleep Disorders, and Urinary Complications.

Selected Topics

Resources

Funding Opportunities

No matching Funding Opportunities were found.

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Grantee Details

PI Name Sort descending PI Organization Title Grant Number Program Official
Cheville, Andrea Lynne

Mayo Clinic Rochester
United States

Achieving Safe, Comprehensive, Digitally-Enabled Cancer Pain managemeNT” (ASCENT) Clinical Trial 5R33CA278594-04 Brennan Streck, Ph.D., RN, M.P.H.
Chong, Catherine Daniela

Mayo Clinic Arizona
United States

Biomarker Signature to Predict the Persistence of Post-Traumatic Headache 5R33NS113315-03 Brandy Heckman-Stoddard, Ph.D., M.P.H.
Clare, Susan E.

Northwestern University At Chicago
United States

Lipid-initiated epigenetic reprogramming of the breast to a neural phenotype 1R21CA288676-01A1
Cohen, Lorenzo

University Of Tx Md Anderson Can Ctr
United States

Opioid-Sparing Effects of Nurse-Delivered Hypnosis During Breast Cancer Surgery 5R01CA272565-03 Brennan Streck, Ph.D., RN, M.P.H.
Crowder, Sylvia

H. Lee Moffitt Cancer Ctr & Res Inst
United States

The MIND-BC Study: MIND diet for Breast cancer Cognition 1R01CA299480-01 Nancy J. Emenaker, Ph.D., RDN, LD, FAND
Damaj, M. Imad

Virginia Commonwealth University
United States

Targeting Sphingosine-1-phosphate (S1P1) receptors for the treatment of Aromatase Inhibitors-induced Musculoskeletal Symptoms 5R01CA272147-03 Rachel Altshuler, Ph.D.
Damaj, M. Imad

Virginia Commonwealth University
United States

Inhibition of NLRP3 inflammasome for the treatment of Chemotherapy-induced peripheral neuropathy 1R21CA296516-01 Rachel Altshuler, Ph.D.
Delaney, Joe R

Medical University Of South Carolina
United States

Biologic rationale of fallopian tube removal to prevent uterine serous carcinoma 1R21CA292343-01A1 Goli Samimi, Ph.D., M.P.H.
Deng, Gary E

University Of California-Irvine
United States

Acupuncture to Improve Outcomes in Patients with Sepsis: a Randomized Controlled Trial 7R21CA286330-03 Goli Samimi, Ph.D., M.P.H.
Duan, Bin

University Of Nebraska Medical Center
United States

Flupirtine Analogue Synthesis and Screening for the Treatment of Chemotherapy-Induced Neuropathic Pain 1R21CA298918-01 Rachel Altshuler, Ph.D.
Duvall, Adam S.

University Of Chicago
United States

Tailoring a fun and engaging tech-assisted cognitive behavioral therapy program for adolescents and young adults with hematological malignancies: A planning grant 1R34CA297498-01 Brennan Streck, Ph.D., RN, M.P.H.
Eisenmann, Eric Daniel

Ohio State University
United States

Damage-associated molecular patterns in chemotherapy toxicity 1R37CA299879-01 Rachel Altshuler, Ph.D.
Eldridge, Ronald C

Emory University
United States

Integrative Multi-Omics of Metabolomics and Epigenetics to Explore thePathophysiology of Cachexia and Survival in Head and Neck SquamousCell Carcinoma 1R03CA304028-01 Marjorie Perloff, M.D.
Elswick, Ronald K

Virginia Commonwealth University
United States

A Randomized Controlled Trial using a Heuristic Tool To Improve Symptom Self-Management in Adolescents and Young Adults with Cancer 5R01CA286799-03 Asad Umar, D.V.M., Ph.D.
Flory, James H

Sloan-Kettering Inst Can Research
United States

Managing metabolic disruption in pancreatic cancer to prevent weight loss and improve quality of life 5R21CA277464-02 Gabriela Riscuta, M.D., CNS

Clinical Trials

Status
Title Sort descending Intervention Sponsor Status
A Web-based Program to Help Caregivers of Lung Patients Learn About Available Supportive Care Resources Internet-Based Intervention - CONNECT, Patient Navigation, Support for Caregiver - Generic List, Support for Caregiver - Personalized List Wake Forest University Health Sciences Enrolling by invitation
Additional Support Program Via Text Messaging and Telephone-Based Counseling for Breast Cancer Patients Receiving Hormonal Therapy Best Practice, Educational Intervention, Motivational Interviewing, Quality-of-Life Assessment, Questionnaire Administration, Text Message-based Navigation Intervention Alliance for Clinical Trials in Oncology Active, not recruiting
An Internet-based Program to Help Cancer Survivors Manage Pain Internet-based pain coping skills program Wake Forest University Health Sciences Recruiting
An Observational Research Study to Uncover Subtypes of Cancer Cachexia Biospecimen Collection, Computed Tomography, Electronic Medical Record, Medical Device Usage and Evaluation, Physical Performance Testing, Positron Emission Tomography, Survey Administration University of Rochester NCORP Research Base Recruiting
Assessing Benefits and Harms of Cannabis/Cannabinoid Use Among Cancer Patients Treated in Community Oncology Clinics Non-interventional Study Wake Forest University Health Sciences Recruiting
Assessing Compliance With Mercaptopurine Treatment in Younger Patients With Acute Lymphoblastic Leukemia in First Remission Behavioral Intervention, Compliance Monitoring, Laboratory Biomarker Analysis, Mercaptopurine, Questionnaire Administration, Standard Follow-Up Care Children's Oncology Group Active, not recruiting
Assessment of Cognitive Function in Breast Cancer and Lymphoma Patients Receiving Chemotherapy University of Rochester NCORP Research Base Enrolling by invitation
Axillary Reverse Mapping in Preventing Lymphedema in Patients with Breast Cancer Undergoing Axillary Lymph Node Dissection Axillary Lymph Node Dissection, Isosulfan Blue, Mapping, Quality-of-Life Assessment, Questionnaire Administration Alliance for Clinical Trials in Oncology Active, not recruiting
Bupropion to Reduce Cancer Related Fatigue in Cancer Survivors Biospecimen Collection, Bupropion Hydrochloride Controlled-release, Placebo Administration, Quality-of-Life Assessment, Questionnaire Administration University of Rochester NCORP Research Base Recruiting
Cancer and Blood Pressure Management, CARISMA Study Best Practice, Blood Pressure Measurement, Clinical Management, Quality-of-Life Assessment, Questionnaire Administration ECOG-ACRIN Cancer Research Group Active, not recruiting