A research blog from the NCI Division of Cancer Prevention Subscribe Researchers Seek to Care for the Whole Patient August 10, 2022 | By Jack J. Lee, Ph.D. In 2012, Patricia Ganz, M.D., saw a 39-year-old cancer survivor for a consultation who had a long-term history of anxiety during medical visits. The woman had been diagnosed with Hodgkin lymphoma when she was 23 years old. Though her treatment was successful, the cancer returned when she was 25. She received high-dose chemotherapy, a stem cell transplant, and full-dose radiation therapy to the chest. This treatment increased her risk for heart damage and breast cancer. Dr. Ganz recommended continued monitoring for potential late medical effects, as well as psychosocial consultation for her chronic anxiety and symptoms of post-traumatic stress. Rising Endometrial Cancer Rates Spur New Approaches to Prevention June 28, 2022 | By Jack J. Lee, Ph.D. Unlike many other cancers, the incidence and death rates for uterine cancer are rising. Rates of new uterine cancer cases have risen 0.6% per year from 2010-2019, and death rates have risen an average of 1.7% per year for the same time frame. Over 90% of uterine cancers begin in the endometrium, the tissue lining the uterus. There are two main subtypes of endometrial cancer, endometrioid and nonendometrioid, and the subtypes are showing different trends, a recent NCI-led study found. Large Studies Evaluating How to Personalize Breast Cancer Screening for All Women May 6, 2022 | By DCP Staff In the era of personalized medicine, prevention and screening for breast cancer are evolving toward new approaches that assess each woman’s risk and lifestyle factors. All women do not carry the same risk for the same type of breast cancer. The old one-size-fits-all screening method can miss the most aggressive forms of the disease, or result in overdiagnosis of indolent disease. How Precision Cancer Prevention Can Promote Health Equity April 18, 2022 | By Jack J. Lee, Ph.D. Overall, cancer death rates in the United States have been declining about 2% per year, current SEER data from 2014 through 2018 show. However, these improvements have not been experienced equally by everyone, which is one of the reasons that April is Minority Cancer Awareness Month, when we call attention to these disparities. Engineering Synthetic Biomarkers for Early Detection of Cancers February 9, 2022 | By Jack J. Lee, Ph.D. Tumor cells release telltale molecules into blood, urine, and other bodily fluids. But it can be difficult to detect tumor-derived DNA, RNA, and proteins in the earliest stages of disease, when cancers can be easier to treat and cure. Earlier stages shed fewer cancer cells—and fewer tumor markers. “Endogenous markers may be there, but not detectable with current technology,” said Sudhir Srivastava, Ph.D., M.P.H., chief of the Cancer Biomarkers Research Group in the NCI Division of Cancer Prevention. The clinical detection of tumors is limited to masses larger than roughly one centimeter in diameter, which can reflect ten years of growth after the tumor first develops. Identifying New Biomarkers to Detect Lung Cancer Earlier January 14, 2022 | By Jack J. Lee, Ph.D. Lung cancer, the leading cause of cancer deaths worldwide killing 1.8 million people each year, is often diagnosed at an advanced stage when the chances for a cure are limited. In the United States, almost 60% of people diagnosed with localized lung and bronchus cancer are likely to survive for 5 years. This is nearly 10 times more than those who are not diagnosed until their cancer has spread to distant parts of the body, who have a 5-year relative survival of 6.3%. Right now, more than half of lung cancers are diagnosed at this late state. Ending Cancer as We Know It Is the Work of Many Capable Hands: A Moment to Say "Thank You" December 20, 2021 | By Philip E. Castle, Ph.D., M.P.H. Fifty years ago this week, the National Cancer Act was signed into law, kick-starting research that has changed how cancer is prevented, detected, diagnosed, treated, and survived, and moving us closer to a time when no one dies of cancer. Starting in March of this year, we, the NCI Division of Cancer Prevention, honored the champions and changemakers of prevention, detection, and supportive care science, including those who focused on cancer health disparities in these areas. When we brainstormed who should be included among the individuals who gave years of their lives and work to ending cancer, we came up with more names than we could feature in one year. Studies Focus on Testing Family Members of Cancer Gene Carriers November 29, 2021 | By DCP Staff If your family member had cancer, would you want to know if you carried a gene mutation that increased your risk of the same cancer? This question is at the heart of three novel research projects underway to determine how best to connect with the family members of women with ovarian cancer so they can decide whether to get genetic testing and counseling about their own risk of cancer. Equity and Access to Trials Highlight the 2021 NCORP Grantee Meeting November 10, 2021 | By DCP Staff The NCI Community Oncology Research Program (NCORP) annual meeting for grantees in August 2021 virtually brought together representatives from every NCORP Research Base and Community and Minority Underserved Site to discuss and learn about a range of topics. Study Seeks to Unravel the Complexity of Rare Blood Disorders Known as Myelodysplastic Syndromes (MDS) October 5, 2021 | By Susan Jenks In a clinical study underway, scientists hope to unravel the complexities of a group of poorly understood and relatively rare blood disorders that often lead to cancer. In myelodysplastic syndromes (MDS), the problem arises when normal blood cells fail to function properly or are ill-formed inside the spongy bone marrow where blood production begins, leaving patients vulnerable to infection, anemia or easy bleeding. Pagination « First First page ‹ Previous Previous page 1 2 3 4 … Next › Next page Last » Last page
