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Supportive Care and Symptom Management

The Supportive Care and Symptom Management program supports studies on the prevention or treatment of acute and chronic symptoms and morbidities related to cancer and its treatment. This includes the impact on the quality of life of patients and their informal caregivers. The program also supports studies of patients and their caregivers at the end of life.

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About Supportive Care and Symptom Management

The program supports research in three areas: prevention or treatment of acute or chronic symptoms and morbidities related to cancer, its treatment and caregiving (symptom management research); effects on quality of life from cancer, its treatment and caregiving (quality of life research); and end-of-life psychosocial issues, caregiving and treatment strategies (end-of-life research).

Through the NCI Community Oncology Research Program (NCORP), clinical trials are underway to evaluate therapies to prevent or ameliorate a broad range of symptoms and/or toxicities associated with cancer its treatment and caregiving. Other studies funded separately are investigating a range of treatment effects on health-related quality of life and a variety of influences on the end-of-life cancer experience. 

Topic Areas include: Anorexia, Cachexia, Cardiotoxicity, Caregiver Issues, Cognitive Dysfunction, Distress/Anxiety/Depression, End of Life, Fatigue, Geriatrics, Hot Flashes, Lymphedema, Medication Adherence, Mucositis, Multiple Symptoms, Musculoskeletal Symptoms, Nausea, Neuropathy, Nutrition, Oral Complications, Other Supportive Care Issues, Pain, Palliative Care, Pediatrics/Adolescents/Young Adult, Physical Functioning, Quality of Life, Skin Toxicities, Sleep Disorders, and Urinary Complications.

Selected Topics

Resources

Funding Opportunities

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Grantee Details

PI Name PI Organization Title Grant Number Program Official
Duan, Bin

University Of Nebraska Medical Center
United States

Flupirtine Analogue Synthesis and Screening for the Treatment of Chemotherapy-Induced Neuropathic Pain 1R21CA298918-01 Rachel Altshuler, Ph.D.
Crowder, Sylvia

H. Lee Moffitt Cancer Ctr & Res Inst
United States

The MIND-BC Study: MIND diet for Breast cancer Cognition 1R01CA299480-01 Nancy J. Emenaker, Ph.D., RDN, LD, FAND
Eisenmann, Eric Daniel

Ohio State University
United States

Damage-associated molecular patterns in chemotherapy toxicity 1R37CA299879-01 Rachel Altshuler, Ph.D.
Kolb, Noah Allan

University Of Vermont & St Agric College
United States

Remote Monitoring of Management of Chemotherapy induced Peripheral Neuropathy 5R01CA247517-05 Brennan Streck, Ph.D., RN, M.P.H.
Groninger, J. Hunter

Medstar Health Research Institute
United States

Cognitive behavioral theory-assisted virtual reality for chronic cancer pain (VR-CAN): device prototype development and feasibility testing 1R21CA299799-01 Brennan Streck, Ph.D., RN, M.P.H.
Pfleger, Cathie M

Icahn School Of Medicine At Mount Sinai
United States

A Drosophila model for Aromatase Inhibitor-induced Musculoskeletal Pain 1R21CA303409-01 Rachel Altshuler, Ph.D.
Hall, Daniel Lee

Massachusetts General Hospital
United States

Innovating CBT-I for Cancer Survivors: An Optimization Trial 5R21CA279248-02
Cao, Weidan

Ohio State University
United States

Treatment-Related Cardiotoxicity Risk Prediction for Breast Cancer Patients with a Multimodal AI-based System 1R01CA301579-01 Eileen Dimond, R.N., M.S.
Veiseh, Omid

Rice University
United States

Bioengineered lymphatic regenerating platform for treatment of breast cancer related lymphedema 1R01HL179534-01 Goli Samimi, Ph.D., M.P.H.
Duvall, Adam S.

University Of Chicago
United States

Tailoring a fun and engaging tech-assisted cognitive behavioral therapy program for adolescents and young adults with hematological malignancies: A planning grant 1R34CA297498-01 Brennan Streck, Ph.D., RN, M.P.H.
Siskind, Leah J

University Of Louisville
United States

Protecting the kidney from cisplatin induced injury and progression to chronic kidney disease 1R01CA305985-01 Marjorie Perloff, M.D.
Shelby, Rebecca A

Duke University
United States

Improving outcomes for women experiencing premature or early menopause after cancer: development and pilot testing of a novel intervention 1R21CA301298-01 Goli Samimi, Ph.D., M.P.H.
Elswick, Ronald K

Virginia Commonwealth University
United States

A Randomized Controlled Trial using a Heuristic Tool To Improve Symptom Self-Management in Adolescents and Young Adults with Cancer 5R01CA286799-03 Asad Umar, D.V.M., Ph.D.
Penedo, Frank J

University Of Miami Coral Gables
United States

eHealth Supported Mindfulness-based Music Therapy Intervention (eMBMT) in Hemopoietic Stem Cell Transplant Patients 4R33CA263335-03 Asad Umar, D.V.M., Ph.D.
Brinkman, Tara M

St. Jude Children'S Research Hospital
United States

Culturally adapted mobile treatment of chronic pain in adolescent survivors of pediatric bone sarcoma 4R33CA280978-02 Rachel Altshuler, Ph.D.

Clinical Trials

Status
Title Intervention Sort descending Sponsor Status
Pathways, a Hope Intervention to Support Personal Goal Pursuit, Mental Health, and Quality of Life During Advanced Lung Cancer Treatment Enhanced Usual Care, Pathways Laurie McLouth Recruiting
Methylphenidate and Exercise in Reducing Cancer-Related Fatigue in Patients With Prostate Cancer Exercise Intervention, Methylphenidate, Placebo, Quality-of-Life Assessment, Questionnaire Administration, Stretching M.D. Anderson Cancer Center Active, not recruiting
Comparing Single vs Multiple Dose Radiation for Cancer Patients With Brain Metastasis and Receiving Immunotherapy fractionated stereotactic radiosurgery (FSRS), single fraction stereotactic radiosurgery (SSRS) Wake Forest University Health Sciences Recruiting
Haloperidol and Lorazepam in Controlling Symptoms of Persistent Agitated Delirium in Patients With Advanced Cancer Undergoing Palliative Care Haloperidol, Lorazepam, Placebo, Quality-of-Life Assessment, Questionnaire Administration M.D. Anderson Cancer Center Active, not recruiting
Reaching Rural Cancer Survivors Who Smoke Using Text-Based Program Health Promotion and Education, Informational Intervention, Questionnaire Administration, Smoking Cessation Intervention Alliance for Clinical Trials in Oncology Recruiting
Developing an Internet-Delivered Sexual Health Program for Breast Cancer Survivors, SHINE Trial Internet-based Intervention Wake Forest University Health Sciences Active, not recruiting
A Web-based Program to Help Caregivers of Lung Patients Learn About Available Supportive Care Resources Internet-Based Intervention - CONNECT, Patient Navigation, Support for Caregiver - Generic List, Support for Caregiver - Personalized List Wake Forest University Health Sciences Active, not recruiting
An Internet-based Program to Help Cancer Survivors Manage Pain Internet-based pain coping skills program Wake Forest University Health Sciences Recruiting
New Assessment System in Measuring Symptom Distress in Cancer Patients Interview, Quality-of-Life Assessment, Questionnaire Administration M.D. Anderson Cancer Center Recruiting
Nutrition Therapy in Improving Immune System in Patients With Bladder Cancer That Can Be Removed by Surgery Laboratory Biomarker Analysis, Nutritional Intervention, Placebo Administration, Quality-of-Life Assessment, Questionnaire Administration SWOG Cancer Research Network Active, not recruiting