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Supportive Care and Symptom Management

The Supportive Care and Symptom Management program supports studies on the prevention or treatment of acute and chronic symptoms and morbidities related to cancer and its treatment. This includes the impact on the quality of life of patients and their informal caregivers. The program also supports studies of patients and their caregivers at the end of life.

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About Supportive Care and Symptom Management

The program supports research in three areas: prevention or treatment of acute or chronic symptoms and morbidities related to cancer, its treatment and caregiving (symptom management research); effects on quality of life from cancer, its treatment and caregiving (quality of life research); and end-of-life psychosocial issues, caregiving and treatment strategies (end-of-life research).

Through the NCI Community Oncology Research Program (NCORP), clinical trials are underway to evaluate therapies to prevent or ameliorate a broad range of symptoms and/or toxicities associated with cancer its treatment and caregiving. Other studies funded separately are investigating a range of treatment effects on health-related quality of life and a variety of influences on the end-of-life cancer experience. 

Topic Areas include: Anorexia, Cachexia, Cardiotoxicity, Caregiver Issues, Cognitive Dysfunction, Distress/Anxiety/Depression, End of Life, Fatigue, Geriatrics, Hot Flashes, Lymphedema, Medication Adherence, Mucositis, Multiple Symptoms, Musculoskeletal Symptoms, Nausea, Neuropathy, Nutrition, Oral Complications, Other Supportive Care Issues, Pain, Palliative Care, Pediatrics/Adolescents/Young Adult, Physical Functioning, Quality of Life, Skin Toxicities, Sleep Disorders, and Urinary Complications.

Selected Topics

Resources

Funding Opportunities

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Grantee Details

PI Name Sort descending PI Organization Title Grant Number Program Official
Penedo, Frank J

University Of Miami Coral Gables
United States

eHealth Supported Mindfulness-based Music Therapy Intervention (eMBMT) in Hemopoietic Stem Cell Transplant Patients 4R33CA263335-03 Asad Umar, D.V.M., Ph.D.
Peppone, Luke Joseph

University Of Rochester
United States

High-dose Vitamin D Supplementation for ADT-Induced Bone Loss in Older Prostate Cancer Patients 5R01CA258349-04 Brandy Heckman-Stoddard, Ph.D., M.P.H.
Perez-Lougee, Giselle Katiria

Massachusetts General Hospital
United States

Thriving Beyond Treatment: A Resilience-Based Approach to Improve Long-term Quality of Life in Post-treatment Lymphoma Survivorship 1R37CA303094-01 Marjorie Perloff, M.D.
Perkins, Susan M

Indiana University Indianapolis
United States

Evaluation of the Communication Plan Early through End-of-Life (COMPLETE) Intervention 5R01CA235632-06 Brennan Streck, Ph.D., RN, M.P.H.
Pfleger, Cathie M

Icahn School Of Medicine At Mount Sinai
United States

A Drosophila model for Aromatase Inhibitor-induced Musculoskeletal Pain 1R21CA303409-01 Rachel Altshuler, Ph.D.
Phillips, Nicholas S

St. Jude Children'S Research Hospital
United States

Cardiopulmonary function and cerebral blood flow in Hodgkin Lymphoma survivors 5R21CA280230-02 Eileen Dimond, R.N., M.S.
Pistilli, Emidio Edward

West Virginia University
United States

Targeting Muscle Fatigability During Cachexia 5R01AR079445-04 Brandy Heckman-Stoddard, Ph.D., M.P.H.
Plas, Ellen Van Der

Arkansas Children'S Hospital Res Inst
United States

Identifying markers of abnormal neurocognitive trajectories during chemotherapy treatment of childhood acute lymphoblastic leukemia 5R37CA266135-04 Asad Umar, D.V.M., Ph.D.
Porter, Laura S

Duke University
United States

Couple Communication Skills Training for Advanced Cancer 5R01CA229425-05 Brennan Streck, Ph.D., RN, M.P.H.
Pozdeyev, Nikita

University Of Colorado Denver
United States

Genetic architecture of thyroid cancer and its clinical utility 5R21CA282380-02 Wendy Wang, Ph.D., M.Sc.
Prigerson, Holly Gwen

Weill Medical Coll Of Cornell Univ
United States

Behavioral and Psychosocial Effects on Study Outcomes in End-Stage Cancer Treatment (BEST End-Stage Cancer Study) 5R35CA197730-11 Brennan Streck, Ph.D., RN, M.P.H.
Pyter, Leah M

Ohio State University
United States

Chemotherapy-induced circadian master clock disruptions and fatigue 3R01CA270372-03S1 Marjorie Perloff, M.D.
Reb, Anne

Beckman Research Institute/City Of Hope
United States

A Blended e-Health Intervention for Fear of Progression in Advanced GYN Cancer 1R21CA293326-01 Brennan Streck, Ph.D., RN, M.P.H.
Rini, Christine

Northwestern University At Chicago
United States

Mosaic: RCT of a Digital Health Intervention Delivering Peer Support Narratives and Psychoeducation to English- and Spanish-Speaking Stem Cell Transplant Recipients 5R01CA292116-02 Brennan Streck, Ph.D., RN, M.P.H.
Rini, Christine

Northwestern University At Chicago
United States

Web-based Pain Coping Skills Training to Improve Pain and Poor Adherence caused by Aromatase Inhibitor-Associated Arthralgia In Breast Cancer Survivors (SKIP-Arthralgia): A Randomized Controlled Trial 5R01CA271220-04 Brennan Streck, Ph.D., RN, M.P.H.

Clinical Trials

Status
Title Sort descending Intervention Sponsor Status
Methylphenidate and Exercise in Reducing Cancer-Related Fatigue in Patients With Prostate Cancer Exercise Intervention, Methylphenidate, Placebo, Quality-of-Life Assessment, Questionnaire Administration, Stretching M.D. Anderson Cancer Center Active, not recruiting
Mobile Health and Social Media Physical Activity Intervention Among Adolescent and Young Adult Childhood Cancer Survivors, the StepByStep Study Educational Intervention, FitBit, Goal Setting, Health Promotion and Education, Media Intervention, Telephone-Based Intervention Children's Oncology Group Active, not recruiting
Mobile Health for Adherence in Breast Cancer Patients Electronic Health Record Review, Health Promotion and Education, Health Telemonitoring, Interview, Patient Navigation, Survey Administration, Text Message-Based Navigation Intervention ECOG-ACRIN Cancer Research Group Recruiting
Monitoring Symptoms to Help Young Women Take Hormone Therapy for Stage I-III Breast Cancer, ASPEN Study Best Practice, Biospecimen Collection, Endocrine Drug Therapy, Health Education, Questionnaire Administration, Symptom Specific Assessment Tool SWOG Cancer Research Network Active, not recruiting
Mosaic Trial for Stem Cell Transplant Recipients Enhanced Usual Care (Control) Website, Intervention website Northwestern University Recruiting
Myopenia and Mechanisms of Chemotherapy Toxicity in Older Adults With Colorectal Cancer Wake Forest University Health Sciences Recruiting
Naloxegol in Treating Patients With Stage IIIB-IV Non-small Cell Lung Cancer Naloxegol, Placebo, Laboratory Biomarker Analysis, Quality-of-Life Assessment Alliance for Clinical Trials in Oncology Active, not recruiting
Neuropsychological and Behavioral Testing in Younger Patients With Cancer Cognitive Assessment, Quality-of-Life Assessment Children's Oncology Group Active, not recruiting
New Assessment System in Measuring Symptom Distress in Cancer Patients Interview, Quality-of-Life Assessment, Questionnaire Administration M.D. Anderson Cancer Center Recruiting
Nutrition Therapy in Improving Immune System in Patients With Bladder Cancer That Can Be Removed by Surgery Laboratory Biomarker Analysis, Nutritional Intervention, Placebo Administration, Quality-of-Life Assessment, Questionnaire Administration SWOG Cancer Research Network Active, not recruiting