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Supportive Care and Symptom Management

The Supportive Care and Symptom Management program supports studies on the prevention or treatment of acute and chronic symptoms and morbidities related to cancer and its treatment. This includes the impact on the quality of life of patients and their informal caregivers. The program also supports studies of patients and their caregivers at the end of life.

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About Supportive Care and Symptom Management

The program supports research in three areas: prevention or treatment of acute or chronic symptoms and morbidities related to cancer, its treatment and caregiving (symptom management research); effects on quality of life from cancer, its treatment and caregiving (quality of life research); and end-of-life psychosocial issues, caregiving and treatment strategies (end-of-life research).

Through the NCI Community Oncology Research Program (NCORP), clinical trials are underway to evaluate therapies to prevent or ameliorate a broad range of symptoms and/or toxicities associated with cancer its treatment and caregiving. Other studies funded separately are investigating a range of treatment effects on health-related quality of life and a variety of influences on the end-of-life cancer experience. 

Topic Areas include: Anorexia, Cachexia, Cardiotoxicity, Caregiver Issues, Cognitive Dysfunction, Distress/Anxiety/Depression, End of Life, Fatigue, Geriatrics, Hot Flashes, Lymphedema, Medication Adherence, Mucositis, Multiple Symptoms, Musculoskeletal Symptoms, Nausea, Neuropathy, Nutrition, Oral Complications, Other Supportive Care Issues, Pain, Palliative Care, Pediatrics/Adolescents/Young Adult, Physical Functioning, Quality of Life, Skin Toxicities, Sleep Disorders, and Urinary Complications.

Selected Topics

Resources

Funding Opportunities

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Grantee Details

PI Name PI Organization Sort descending Title Grant Number Program Official
Bao, Ting

Dana-Farber Cancer Inst
United States

Yoga for Chemotherapy-induced Peripheral Neuropathy Treatment (YCT) Trial 5R01CA251470-06 Goli Samimi, Ph.D., M.P.H.
Xu, Chunhui

Emory University
United States

High-throughput assessment of chemotherapy-induced cardiotoxicity in 3D human cardiomyocytes 1R21CA285254-01A1 Eileen Dimond, R.N., M.S.
Ligibel, Jennifer A.

Dana-Farber Cancer Inst
United States

Distance-based Exercise to preserve Function and prevENt Disability (DEFEND) 5U34CA293568-02 Brandy Heckman-Stoddard, Ph.D., M.P.H.
Eisenmann, Eric Daniel

Ohio State University
United States

Damage-associated molecular patterns in chemotherapy toxicity 1R37CA299879-01 Rachel Altshuler, Ph.D.
Vijayvergia, Namrata

Research Inst Of Fox Chase Can Ctr
United States

Exploring the Neuroprotective Potential of CBD in Preventing Oxaliplatin-Induced Neuropathy: A Prospective Study 1R21CA292276-01A1 Rachel Altshuler, Ph.D.
Meghani, Salimah H.

University Of Pennsylvania
United States

Cannabis use and outcomes in ambulatory patients with cancer: A 12-month cohort study 3R01CA270483-04S1 Gabriela Riscuta, M.D., CNS
Chan, Alexandre

University Of California-Irvine
United States

Neurotrophic strategy to mitigate chemotherapy-related brain injury 5R01CA276212-03 John Clifford, Ph.D.
Mehrara, Babak J

Sloan-Kettering Inst Can Research
United States

Mechanisms of racial disparity in breast cancer-related lymphedema 5R01CA278599-04 Asad Umar, D.V.M., Ph.D.
Peppone, Luke Joseph

University Of Rochester
United States

High-dose Vitamin D Supplementation for ADT-Induced Bone Loss in Older Prostate Cancer Patients 5R01CA258349-05 Brandy Heckman-Stoddard, Ph.D., M.P.H.
Blanke, Charles D.

Oregon Health & Science University
United States

SWOG NCORP Research Base 3UG1CA189974-11S1 Brandy Heckman-Stoddard, Ph.D., M.P.H.
Reb, Anne

Beckman Research Institute/City Of Hope
United States

A Blended e-Health Intervention for Fear of Progression in Advanced GYN Cancer 1R21CA293326-01 Brennan Streck, Ph.D., RN, M.P.H.
Kang, Dongkyun

University Of Arizona
United States

Non-invasive, quantitative microscopic biomarkers for chemotherapy-induced peripheral neuropathy 1R01CA301271-01 Rachel Altshuler, Ph.D.
Shelby, Rebecca A

Duke University
United States

Improving outcomes for women experiencing premature or early menopause after cancer: development and pilot testing of a novel intervention 1R21CA301298-01 Goli Samimi, Ph.D., M.P.H.
Im, Eun-Ok

University Of Texas At Austin
United States

Cancer Pain Management: A Technology-Based Intervention for Asian American Breast Cancer Survivors 5R33CA280979-04 Brennan Streck, Ph.D., RN, M.P.H.
Infante, Rodney E

Ut Southwestern Medical Center
United States

Identifying the Cellular and Molecular Targets of JAK/STAT-Driven Adipose Wasting to Reverse Cancer Cachexia 3R01CA266900-04S1 Marjorie Perloff, M.D.

Clinical Trials

Status
Title Intervention Sponsor Status
Relaxation for Women With Breast Cancer Undergoing Radiotherapy Questionnaires, Relaxation Program, Saliva Testing M.D. Anderson Cancer Center Active, not recruiting
Reproductive Health Program in Patients With Cancer Standard practice related to reproductive heath, Training modules, algorithm, referral development ECOG-ACRIN Cancer Research Group Active, not recruiting
REVITALIZE: RCT to Reduce Fatigue in Adults With Ovarian Cancer on PARP Inhibitors Educational Materials, REVITALIZE Intervention Dana-Farber Cancer Institute Recruiting
S1501 Dual Observational and Randomized Cohort Study of Patients With Metastatic HER-2+ Breast Cancer at Risk of Cardiac Toxicity Carvedilol, Laboratory Biomarker Analysis, Patient Observation SWOG Cancer Research Network Recruiting
Simplified Patient Care Strategy in Decreasing Early Death in Patients With Acute Promyelocytic Leukemia Laboratory Biomarker Analysis, Simplified Patient Care Strategy ECOG-ACRIN Cancer Research Group Active, not recruiting
Studying the Effect of Levocarnitine in Protecting the Liver From Chemotherapy for Leukemia or Lymphoma Biospecimen Collection, Calaspargase Pegol, Levocarnitine, Pegaspargase, Quality-of-Life Assessment Children's Oncology Group Recruiting
Studying the Physical Function and Quality of Life Before and After Surgery in Patients With Stage I Cervical Cancer Conization, Quality-of-Life Assessment, Questionnaire Administration, Therapeutic Conventional Surgery, Therapeutic Lymphadenectomy GOG Foundation Active, not recruiting
Surgical Thromboprophylaxis Practices in Oncology Patients Within the NCORP Network, STOP-VTE Study Non-Interventional Study Wake Forest University Health Sciences Recruiting
Taxane and Taxane-Induced Peripheral Neuropathy in African American Patients With Stage I-III Breast Cancer Docetaxel, Paclitaxel, Quality-of-Life Assessment, Questionnaire Administration ECOG-ACRIN Cancer Research Group Active, not recruiting
Telephone Support in Advanced Gastrointestinal Cancer Acceptance and Commitment Therapy, Education/Support Indiana University Recruiting