NCI Community Oncology Research Program
Community Oncology and Prevention Trials
SWOG Cancer Research Network
For more information, see ClinicalTrials.gov NCT05455606
This clinical trial studies how well an educationally enhanced genomic tumor board (EGTB) intervention works to increase the number of patients with solid tumors that have come back (recurrent), do not respond to treatment (refractory), have spread to other parts of the body (metastatic), or are newly diagnosed and spread to other parts of the body (advanced) who receive genome-informed treatment. Genome-informed treatment refers to treatment based on the information found in genomic tumor test results. This study compares the usual approach to reviewing genomic tumor test results with the approach of having a genomic tumor board (GTB) review the test results. A GTB is team of doctors and scientists that have experience in understanding genomic changes and review genomic tumor test results. The tumor board helps to suggest whether there are other cancer treatment options based on patient genetic test results. The usual approach is to review genomic tumor test results without the GTB being involved. This study may help researchers learn if using a GTB enhances the treatment decision making process within 6 months of joining the study. This study may also help researchers learn if using the GTB increases doctors' understanding of genomic tumor test results and increases doctors' comfort level with genomic tumor tests.
Best Practice, Chart Abstraction, Educational Intervention, Genomic Profile, Interview, Questionnaire Administration, Tumor Board Review
Advanced Malignant Solid Neoplasm, Metastatic Malignant Solid Neoplasm, Recurrent Malignant Solid Neoplasm, Refractory Malignant Solid Neoplasm
Jens Rueter, Bret E. Friday, John M. Schallenkamp, Charles S. Kuzma, Shahzad Siddique, Joshua Lukenbill, Site Public Contact, Vamsi K. Vasireddy, Michael Humeniuk, Francis J. Cuevas, Pamala A. Pawloski, Rose A. Juhasz, Jay W. Carlson, Luis J. Santos Reyes, Gary C. Doolittle, Jami A. Fukui, Bryan A. Faller, Catherine A. Ronaghan