HPV-Based Screen-and-Treat Demonstration Project in Lilongwe

Research Group
Breast and Gynecologic Cancer
UNC Lineberger Comprehensive Cancer Center
Active, not recruiting
ClinicalTrials.gov ID
For more information, see ClinicalTrials.gov NCT04092257
The purpose of this study is to assess completion and performance of the following novel
invasive cervical cancer (ICC) screen-and-treat algorithm among 625 HIV-positive women in
Lilongwe, Malawi: 1) rapid testing of self-collected vaginal brush for primary high risk
(hr)-human papillomavirus (HPV), 2) same-day visual inspection with acetic acid (VIA) for
women who are hr-HPV positive, and 3) thermocoagulation for VIA positive/ablation-eligible
(by cervical colposcopy) women.
VIA and thermocoagulation
HPV Infection, Cervical Cancer, HIV Infections
Lameck Chinula, MD

See list of participating sites