Testing Ramipril to Prevent Memory Loss in People With Glioblastoma

Major Program
Supportive Care and Symptom Management
NCI Community Oncology Research Program
Research Group
Community Oncology and Prevention Trials
Sponsor
Wake Forest University Health Sciences
Status
Active, not recruiting
ClinicalTrials.gov ID
For more information, see ClinicalTrials.gov NCT03475186
This study is to determine if an oral drug called Ramipril can lower the chance of memory loss in patients with glioblastoma getting chemoradiation. Patients will take Ramipril during chemoradiation and continue until 4 months post-treatment. Memory loss will be assessed using several neurocognitive tests throughout the duration of the study.
Intervention
Ramipril
Condition
Glioblastoma, Radiotherapy; Complications, Cognitive Decline, Chemoradiation
Investigators
Michael D Chan, MD

See list of participating sites