CHARM II: Chemotherapy for Ablation and Resolution of Mucinous Pancreatic Cysts

Research Group
Gastrointestinal and Other Cancers
Sponsor
Milton S. Hershey Medical Center
Status
Recruiting
ClinicalTrials.gov ID
For more information, see ClinicalTrials.gov NCT03085004
The purpose of this study is to evaluate the efficacy and safety of chemotherapeutic pancreatic cyst ablation using ethanol lavage followed by the infusion of a dual-agent chemotherapeutic cocktail (paclitaxel + gemcitabine) compared with alcohol-free saline lavage followed by infusion of the same dual-agent chemotherapeutic cocktail (paclitaxel + gemcitabine) for the ablation of pancreatic cystic neoplasms using endoscopic ultrasound guided fine needle infusion (EUS-FNI) for agent delivery.
Intervention
Paclitaxel + Gemcitabine admixture, Ethanol, Normal saline
Condition
Pancreatic Cyst, EUS-FNA
Investigators
Matthew T. Moyer, MD, MS, Sydney Rhoades, BS, John M. DeWitt, MD, Lainna Cohen, MSW

See list of participating sites