Phase 3 Randomized Placebo Controlled Clinical Trial of Donepezil

Major Program(s) or Research Group(s)

  • Community Oncology and Prevention Trials
  • NCI Community Oncology Research Program
  • Supportive Care and Symptom Management

Sponsor

Wake Forest University Health Sciences

Status

Active, not recruiting

ClinicalTrials.gov ID

For more information, see ClinicalTrials.gov NCT02822573

This study is to compare the safety and effects of donepezil (Aricept) for patients reporting
cognitive or memory issues after receiving chemotherapy for breast cancer. Patients will
receive either donepezil or placebo for 24 weeks. The primary objective is to see if memory
improves with the use of donepezil during the study.

Intervention

Donepezil 5 mg, Placebo

Condition

Cognitive Dysfunction, Memory Impairment

Investigators

Stephen R Rapp, PhD

See list of participating sites