Simvastatin in Reducing Pancreatitis in Patients With Recurrent, Acute or Chronic Pancreatitis

This randomized phase II trial studies how well simvastatin works in reducing pancreatitis
(the inflammation of the pancreas) in patients with pancreatitis that occurs more than once
(recurrent), has worsened quickly (acute), or has persisted or progressed over a long period
of time (chronic). Simvastatin may decrease the inflammation of the pancreas by modulating
the immune response responsible for inflammation. It is not yet known if simvastatin may be
an effective treatment for pancreatitis.


Laboratory Biomarker Analysis, Placebo Administration, Quality-of-Life Assessment, Questionnaire Administration, Simvastatin


Acute Pancreatitis


Marc T Goodman

See list of participating sites