Nashville Early Diagnosis Lung Cancer Project

Research Group
Cancer Biomarkers
Vanderbilt-Ingram Cancer Center
Active, not recruiting ID
For more information, see NCT01475500
This screening study will address the lack of molecular strategies for the early detection of lung cancer and integrate those with epidemiological and imaging strategies.

The hypothesis is that the repeated measure of biomarkers of risk obtained from the molecular analysis of biological specimens including those from bronchoscopy (bronchial brushings and biopsies) may contribute to the refinement of high-risk populations and allow an earlier clinical diagnosis.

The goal of the investigators study is to provide screening for lung cancer in a high-risk population. In this prospective cohort it will be tested whether repeated measure of biomarkers of risk allows early detection of lung cancer.
Computerized tomography (CT) scan of the chest, Pulmonary function tests, Nasal brushings, Urine sample, Bronchoscopy, Blood sample collection, Bronchoalveolar lavage, Questionnaire-data collection, Buccal epithelium collection, Sputum sample
Lung Cancer
Eric Grogan, MD

See list of participating sites