Research Group
Cancer Biomarkers
Sponsor
Vanderbilt-Ingram Cancer Center
Status
Active, not recruiting
NCT ID
NCT01475500
This screening study will address the lack of molecular strategies for the early detection of lung cancer and integrate those with epidemiological and imaging strategies.
The hypothesis is that the repeated measure of biomarkers of risk obtained from the molecular analysis of biological specimens including those from bronchoscopy (bronchial brushings and biopsies) may contribute to the refinement of high-risk populations and allow an earlier clinical diagnosis.
The goal of the investigators study is to provide screening for lung cancer in a high-risk population. In this prospective cohort it will be tested whether repeated measure of biomarkers of risk allows early detection of lung cancer.
The hypothesis is that the repeated measure of biomarkers of risk obtained from the molecular analysis of biological specimens including those from bronchoscopy (bronchial brushings and biopsies) may contribute to the refinement of high-risk populations and allow an earlier clinical diagnosis.
The goal of the investigators study is to provide screening for lung cancer in a high-risk population. In this prospective cohort it will be tested whether repeated measure of biomarkers of risk allows early detection of lung cancer.
Intervention
Blood sample collection, Bronchoalveolar lavage, Bronchoscopy, Buccal epithelium collection, Computerized tomography (CT) scan of the chest, Nasal brushings, Pulmonary function tests, Questionnaire-data collection, Sputum sample, Urine sample
Condition
Lung Cancer
Investigators
Eric Grogan, MD