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Consortium for Imaging and Biomarkers (CIB)

The Consortium for Imaging and Biomarkers (CIB) seeks to improve cancer screening, early detection of aggressive cancer, assessment of cancer risk, and cancer diagnosis by integrating imaging strategies with biomarkers into complementary approaches.

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About the Consortium for Imaging and Biomarkers

The Consortium for Imaging and Biomarkers aims to integrate imaging strategies and biomarker methodologies into a singular complementary approach to cancer detection. Investigators Work in multi-disciplinary teams to perform collaborative studies, exchange information, share knowledge and leverage common resources.

Overdiagnosis (finding cancers that will never affect a person’s health) and false positives (test results that show cancer when none is there) present significant clinical problems in the prevention, detection and treatment of cancer. There is a need to more accurately identify early-stage aggressive cancers and distinguish lesions that are life threatening from those that are not.

The Consortium for imaging and Biomarkers Research Units develop, optimize, and clinically validate novel methods to:

  • Detect aggressive cancers at the earliest stages possible;
  • Reduce overdiagnosis;
  • Reduce false positive tests; and
  • Identify lethal cancers from non-lethal disease.

The goal of the Consortium for imaging and Biomarkers is to develop improved methods for the early detection of aggressive cancer by managing overdiagnosis, reducing false positives and identifying lethal cancers from non-lethal disease using strategies aimed at effective integration and validation of imaging and biomarkers.

Funding Opportunity

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Grantee Details

PI Name Sort descending PI Organization Title Grant Number Program Official
Chak, Amitabh

Case Western Reserve University
United States

Pathways of Injury and Repair in Barrett's Carcinogenesis 5P01CA269019-03 Asad Umar, D.V.M., Ph.D.
Chan, Alexandre

University Of California-Irvine
United States

Neurotrophic strategy to mitigate chemotherapy-related brain injury 5R01CA276212-03 John Clifford, Ph.D.
Chan, Alexandre

University Of California-Irvine
United States

Neurotrophic strategy to mitigate chemotherapy-related brain injury 5R01CA276212-03 John Clifford, Ph.D.
Chan, Daniel Wanyui

Johns Hopkins University
United States

Development of a panel of multiplex biomarkers for the early detection of pancreatic ductal adenocarcinoma and high-risk lesions 5U01CA274514-03 Matthew Young, Ph.D.
Chan, Andrew T

Massachusetts General Hospital
United States

Precision Prevention Research Program 5R35CA253185-06 Asad Umar, D.V.M., Ph.D.
Chan, Daniel Wanyui

Johns Hopkins University
United States

BCC for Prostate Cancer: Discovery and Translation of Biomarkers for Clinical Unmet Needs 5U2CCA271895-03 Indu Kohaar, Ph.D., M.Phil., M.Sc.
Chan, Andrew T

Massachusetts General Hospital
United States

MGH- PROSPECT: Pathways, Risk factors, and mOleculeS to Prevent Early-onset Colorectal Tumors 3OT2CA297680-01S1 Asad Umar, D.V.M., Ph.D.
Chapkin, Robert Stephen

Texas A&M Agrilife Research
United States

Targeting plasma membrane spatial dynamics to suppress aberrant Wnt signaling 5R01CA244359-05 Amit Kumar, Ph.D.
Chen, Ru

Baylor College Of Medicine
United States

BLOOD-BASED PROTEOMIC ASSAY FOR PANCREATIC CANCER DETECTION 4UH3CA292130-02 Claire Zhu, Ph.D.
Chen, Grace Y.

University Of Michigan At Ann Arbor
United States

Targeting cancer stem-like cells and inflammation for colon cancer chemoprevention 5R21CA273646-02
Cheville, Andrea Lynne

Mayo Clinic Rochester
United States

Achieving Safe, Comprehensive, Digitally-Enabled Cancer Pain managemeNT” (ASCENT) Clinical Trial 5R33CA278594-04 Brennan Streck, Ph.D., RN, M.P.H.
Cheville, Andrea Lynne

Mayo Clinic Rochester
United States

Achieving Safe, Comprehensive, Digitally-Enabled Cancer Pain managemeNT” (ASCENT) Clinical Trial 5R33CA278594-04 Brennan Streck, Ph.D., RN, M.P.H.
Chiang, Cheng-Ming

Ut Southwestern Medical Center
United States

Small Compound Inhibitors Targeting HPV Genome Replication 1R01CA288743-01A1
Chibwesha, Carla J

Univ Of North Carolina Chapel Hill
United States

Acceptability and feasibility of combination treatment for cervical precancer among South Africa women living with HIV 5R01CA250850-05 Vikrant Sahasrabuddhe, M.B.B.S., M.P.H., Dr.P.H.
Chinnaiyan, Arul M

University Of Michigan At Ann Arbor
United States

Michigan-VUMC Biomarker Characterization Center 5U2CCA271854-04 Indu Kohaar, Ph.D., M.Phil., M.Sc.

Program Contact(s)

Sudhir Srivastava, Ph.D., M.P.H.
Email: sudhir.srivastava@nih.gov

Guillermo Marquez, Ph.D.
Email: guillermo.marquez@nih.gov