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Chemopreventive Agent Development

Designs, develops, implements, and monitors research on interventions that may block, reverse, or delay the early stages of cancer. Investigates nutrients, micronutrients, natural products, pharmacologic agents, biomolecules, and vaccines from preclinical to early-phase I clinical studies. Helps investigators to bridge the gaps between biology and identifying potential targets, and between discovery of targets and agents and clinical testing in people.

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Major Programs

Staff List

Name, Email, Phone Room Group(s)/Office ID
Asefa, Wosene
wosene.asefa@nih.gov
240-276-6422
5E504 Program Support Assistant | Chemopreventive Agent Development 546
Biswas, Kajal, Ph.D.
kajal.biswas2@nih.gov
240-276-5614
5E540 Program Officer | Chemopreventive Agent Development 540
Boring, Daniel, R.Ph., Ph.D. [C]
daniel.boring@nih.gov
240-276-6422
Contractor | Chemopreventive Agent Development 1354
Cholewa, Brian, Ph.D.
brian.cholewa@nih.gov
240-276-7545
5E542 Deputy Chief | Chemopreventive Agent Development 558
Clifford, John, Ph.D.
john.clifford@nih.gov
202-235-4482
5E538 Program Officer | Chemopreventive Agent Development 542
Gunasekharan, Vignesh, Ph.D.
vignesh.gunasekharan@nih.gov
240-276-5814
5E536 Program Officer | Chemopreventive Agent Development 573
Mohammed, Altaf, Ph.D.
altaf.mohammed@nih.gov
240-276-6082
5E602 Program Officer | Chemopreventive Agent Development 594
Nalli, Ancy, Ph.D., M.S.
ancy.nalli@nih.gov
202-276-5265
5E570 Program Officer | Chemopreventive Agent Development 2557
Sei, Shizuko, M.D.
shizuko.sei@nih.gov
240-276-5005
5E452 Co-Chief | Chemopreventive Agent Development 623
Shoemaker, Robert, Ph.D.
robert.shoemaker@nih.gov
240-276-7077
5E454 Co-Chief | Chemopreventive Agent Development
Acting Chief | Nutritional Science
624
Vlad, Anda, M.D., Ph.D.
anda.vlad@nih.gov
240-276-6422
5E546 Program Officer | Chemopreventive Agent Development 2525

Grants

PI Name Sort descending PI Organization Title Grant Number Program Official
Giles, Erin

University Of Michigan At Ann Arbor
United States

Obesity, body fat distribution, and breast cancer risk: is visceral fat the culprit after menopause? 5R01CA269726-02 Marjorie Perloff, M.D.
Gudas, Lorraine J

Weill Medical Coll Of Cornell Univ
United States

CD 1530, an RAR Gamma Agonist for Oral Cavity Squamous Cell Carcinoma Prevention 5R01CA270248-02
Hanks, Brent Allen

Duke University
United States

Role of the tumor NLRP3 inflammasome in the generation of anti-PD-1 antibody immunotherapy-associated toxicities 5R01CA251136-04 Marjorie Perloff, M.D.
Hoshida, Yujin

Ut Southwestern Medical Center
United States

Reverse-engineering precision liver cancer chemoprevention 3R01CA233794-05S1 Marjorie Perloff, M.D.
Hu, Jim

Weill Medical Coll Of Cornell Univ
United States

Pelvic fascia spARing radical prostatectomy TrIAL (PARTIAL) 5R01CA259173-03 Marjorie Perloff, M.D.
Huang, Ying

Western University Of Health Sciences
United States

Preventing UV-induced immunosuppression and skin carcinogenesis with R-carvedilol 5R01CA269653-03
Huberty, Jennifer Lynne

University Of Texas Hlth Science Center
United States

Consumer-based meditation app, Calm, for treatment of sleep disturbance in hematological cancer patients 5R01CA262041-05 Marjorie Perloff, M.D.
Infante, Rodney E

Ut Southwestern Medical Center
United States

Identifying the Cellular and Molecular Targets of JAK/STAT-Driven Adipose Wasting to Reverse Cancer Cachexia 3R01CA266900-03S1 Marjorie Perloff, M.D.
Kassie, Fekadu

University Of Minnesota
United States

Lung cancer prevention and treatment by targeting ALDH1 and CD44 expressing putative lung cancer stem cells 5R01CA231210-05 Marjorie Perloff, M.D.
Kassie, Fekadu

University Of Minnesota
United States

Targeting tumor cell mitochondria for the prevention and treatment of lung cancer 1R01CA285608-01A1
Largaespada, David Andrew

University Of Minnesota
United States

Recurrent Tumor-Specific Alternately Processed Transcripts as a Source of Neoantigens for NF1-associated Malignant Peripheral Nerve Sheath Tumor Immunoprevention 5UH3CA244687-05
Leal, Ana Sofia Mendes

Indiana University Indianapolis
United States

Nrf2, immune cells and lung cancer 7R01CA226690-06 Marjorie Perloff, M.D.
Lindau, Stacy Tessler

University Of Chicago
United States

Bionic Breast Project: A Neuroprosthesis to Restore Touch Sensation and Reduce Chronic Pain After Mastectomy 5R01CA281301-02 Marjorie Perloff, M.D.
Lipkin, Steven M

Weill Medical Coll Of Cornell Univ
United States

CAP-IT Center for LNP RNA Immunoprevention 5U54CA272688-03 John Clifford, Ph.D.
Mcguire, Andrew

Fred Hutchinson Cancer Center
United States

Rational Vaccine Design to prevent HIV-Associated Lymphoma 5R01CA285227-02