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Cancer Immunoprevention Network (CIP-Net)

Wildtype and frameshift mutant Asxl1 mRNA detected by in situ hybridization using RNAScope technology in organoids derived from a mismatch repair-deficient mouse intestinal tumor.

The Cancer Immunoprevention Network (CIP-Net) supports the development of approaches that leverage the immune system to prevent cancers. Research in CIP-Net is advancing a deeper understanding of basic mechanisms of immunoprevention and promoting the discovery of novel immunoprevention strategies. Both the National Cancer Institute Division of Cancer Prevention and the Division of Cancer Biology support researchers in this network.

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About the Cancer Immunoprevention Network

CIP-Net supports projects from basic through translational preclinical research with an emphasis on exploring the biology of early malignancy and addressing the research gap between immunoprevention and immunotherapy.

The overall research objectives of the Network are to:

  • Discover novel immunoprevention pathways and targets
  • Elucidate immune responses to the earliest stages of carcinogenesis
  • Preclinical development and testing of interventions (agents/vaccines)
  • Investigate mechanisms of efficacy and potential side-effects of precision cancer prevention-interception strategies
  • Develop and optimize immunoprevention models
  • Define immune mechanisms of preventive cancer vaccines and immunomodulatory agents

Candidate agents and vaccines that emerge from CIP-Net research may move forward to the PREVENT program for further preclinical development towards clinical trials.

Grantee Details

PI Name Sort descending PI Organization Title Grant Number Program Official
Rogers, Laura Q

University Of Alabama At Birmingham
United States

Role of gut microbe composition in psychosocial symptom response to exercise training in breast cancer survivors 5R01CA235598-06 Gabriela Riscuta, M.D., CNS
Rogers, Laura Q

University Of Alabama At Birmingham
United States

Role of gut microbe composition in psychosocial symptom response to exercise training in breast cancer survivors 5R01CA235598-06 Gabriela Riscuta, M.D., CNS
Rosenberg, Daniel William

University Of Connecticut Sch Of Med/Dnt
United States

Microbiota, Metabolites, and Colon Neoplasia 5R01CA252045-05 Amit Kumar, Ph.D.
Rosenbluth, Jennifer M.

University Of California, San Francisco
United States

In vitro models as a window to learn how to change outcomes in women at high risk of developing breast cancer 4R01CA281361-04 Brandy Heckman-Stoddard, Ph.D., M.P.H.
Ross, Stephen

New York University School Of Medicine
United States

Psilocybin Therapy for Advanced Cancer-related Psychiatric Distress 5R01CA268521-04 Rachel Altshuler, Ph.D.
Ross, Stephen

New York University School Of Medicine
United States

Psilocybin Therapy for Advanced Cancer-related Psychiatric Distress 5R01CA268521-04 Rachel Altshuler, Ph.D.
Rosser, Charles J

Cedars-Sinai Medical Center
United States

A Multiplex Protein Biomarker-Based Immunoassay for the Early Detection of Bladder Cancer and its Implications in Tumor Biology 5R01CA277810-03 Guillermo Marquez, Ph.D.
Rotemberg, Veronica Miriam

Sloan-Kettering Inst Can Research
United States

M-ISIC: A Multimodal Open-Source International Skin Imaging Collaboration Informatics Platform for Automated Skin Cancer Detection 5U24CA264369-04 Guillermo Marquez, Ph.D.
Roth, Michael E.

Public Health Institute
United States

Children's Oncology Group NCI Community Oncology Research Program (NCORP) Research Base grant 3UG1CA189955-11S3 Brandy Heckman-Stoddard, Ph.D., M.P.H.
Roth, Michael E.

Public Health Institute
United States

Children's Oncology Group NCI Community Oncology Research Program (NCORP) Research Base grant 3UG1CA189955-11S3 Brandy Heckman-Stoddard, Ph.D., M.P.H.
Rowland, Kendrith Martin

Carle Foundation
United States

Carle Cancer Center NCI Community Oncology Research Program (NCORP) 3UG1CA189861-11S1 Vanessa A. White, M.P.H.
Rowland, Kendrith Martin

Carle Foundation
United States

Carle Cancer Center NCI Community Oncology Research Program (NCORP) 3UG1CA189861-11S1 Vanessa A. White, M.P.H.
Russell, John A

University Of Wisconsin-Madison
United States

Treatment of Functional Deficits IN tongue muscles induced by radiation and chemoradiation treatment 5R37CA225608-07 Cecilia Lee, Dr.P.H., RN
Russell, John A

University Of Wisconsin-Madison
United States

Treatment of Functional Deficits IN tongue muscles induced by radiation and chemoradiation treatment 5R37CA225608-07 Cecilia Lee, Dr.P.H., RN
Saenger, Yvonne Margaret

Albert Einstein College Of Medicine
United States

Applying pathomics to establish a biosignature for aggressive skin melanoma 5R01CA260375-05 Guillermo Marquez, Ph.D.

Program Contact(s)

Altaf Mohammed, Ph.D.
NCI DCP Chemopreventive Agent Development Research Group
Email: altaf.mohammed@nih.gov
Phone: 240-276-6082
Room: 5E554